Inhibitory effect of PMC, a potent hydrophilic α-tocopherol derivative, on vascular smooth muscle cell proliferation: The pivotal role of PKC-α translocation

References

• Azzi A, Boscoboinik D, Chatelain E, Ozer NK, Stauble B (1993): d-alpha-Tocopherol control of cell proliferation. Mol Aspects Med 14: 265–271.
   PubMed Web of Science ®Google Scholar
• Bjorklund M, Taipale M, Varjosalo M, Saharinen J, Lahdenpera J, Taipale J (2006): Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature 439: 1009–1013.
   Google Scholar
• Carter CA, Kane CJ (2004): Therapeutic potential of natural compounds that regulate the activity of protein kinase C. Curr Med Chem 11: 2883–2902.
   PubMed Web of Science ®Google Scholar
• Churchill E, Budas G, Vallentin A, Koyanagi T, Mochly-Rosen D (2008): PKC isozymes in chronic cardiac disease: Possible therapeutic targets? Ann Rev Pharmacol Toxicol 48: 569–599.
   PubMed Web of Science ®Google Scholar
• Dzau VJ, Braun-Dullaeus RC, Sedding DG (2002): Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies. Nat Med 8: 1249–1256.
   PubMed Web of Science ®Google Scholar
• Goodnight JA, Mischak H, Kolch W, Mushinski JF (1995): Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes. J Biol Chem 270: 9991–10001.
   PubMed Web of Science ®Google Scholar
• Hedin U, Roy J, Tran PK (2004): Control of smooth muscle cell proliferation in vascular disease. Curr Opin Lipidol 15: 559–565.
   PubMed Web of Science ®Google Scholar
• Hsiao G, Huang HY, Fong TH, Shen MY, Lin CH, Teng CM, Sheu JR (2004): Inhibitory mechanisms of YC-1 and PMC in the induction of iNOS expression by lipoteichoic acid in RAW 264.7 macrophages. Biochem Pharmacol 67: 1411–1419.
   PubMed Web of Science ®Google Scholar
• Hsiao G, Lee JJ, Chen YC, Lin JH, Shen MY, Lin KH, Chou DS, Sheu JR (2007): Neuroprotective effects of PMC, a potent alpha-tocopherol derivative, in brain ischemia-reperfusion: Reduced neutrophil activation and anti-oxidant actions. Biochem Pharmacol 73: 682–693.
   PubMed Web of Science ®Google Scholar
• Ingold KU, Burton GW, Foster DO, Hughes L, Lindsay DA, Webb A (1987): Biokinetics of and discrimination between dietary RRR- and SRR-alpha-tocopherols in the male rat. Lipids 22: 163–172.
   PubMed Web of Science ®Google Scholar
• Kastan MB, Bartek J (2004): Cell-cycle checkpoints and cancer. Nature 432: 316–323.
   PubMed Web of Science ®Google Scholar
• Kogure K, Hama S, Kisaki M, Takemasa H, Tokumura A, Suzuki I, Fukuzawa K (2004): Structural characteristic of terminal dicarboxylic moiety required for apoptogenic activity of alpha-tocopheryl esters. Biochim Biophys Acta 1672: 93–99.
   PubMed Web of Science ®Google Scholar
• Kraft AS, Anderson WB (1983): Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane. Nature 301: 621–623.
   PubMed Web of Science ®Google Scholar
• Livneh E, Fishman DD (1997): Linking protein kinase C to cell-cycle control. Eur J Biochem 248: 1–9.
   PubMedGoogle Scholar
• Morgan KG, Leinweber BD (1998): PKC-dependent signalling mechanisms in differentiated smooth muscle. Acta Physiol Scand 164: 495–505.
   PubMedGoogle Scholar
• Mosmann T (1983): Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immuno Meth 65: 55–63.
   PubMed Web of Science ®Google Scholar
• Munteanu A, Zingg JM (2007): Cellular, molecular and clinical aspects of vitamin E on atherosclerosis prevention. Mol Aspects Med 28: 538–590.
   PubMed Web of Science ®Google Scholar
• Munteanu A, Zingg JM, Ogru E, Libinaki R, Gianello R, West S, Negis Y, Azzi A (2004): Modulation of cell proliferation and gene expression by alpha-tocopheryl phosphates: Relevance to atherosclerosis and inflammation. Biochem Biophys Res Comm 318: 311–316.
   PubMed Web of Science ®Google Scholar
• Murray AW (2004): Recycling the cell cycle: Cyclins revisited. Cell 116: 221–234.
   PubMed Web of Science ®Google Scholar
• Nishizuka Y (1995): Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9: 484–496.
   PubMed Web of Science ®Google Scholar
• Okazaki J, Mawatari K, Liu B, Kent KC (2000): The effect of protein kinase C and its alpha subtype on human vascular smooth muscle cell proliferation, migration and fibronectin production. Surgery 128: 192–197.
   PubMed Web of Science ®Google Scholar
• Pauly RR, Bilato C, Cheng L, Monticone R, Crow MT (1997): Vascular smooth muscle cell cultures. Meth Cell Biol 52: 133–154.
   PubMed Web of Science ®Google Scholar
• Ross R (1995): Cell biology of atherosclerosis. Ann Rev Physiol 57: 791–804.
   PubMed Web of Science ®Google Scholar
• Sheu JR, Lee CR, Hsiao G, Hung WC, Lee YM, Chen YC, Yen MH (1999a): Comparison of the relative activities of alpha-tocopherol and PMC on platelet aggregation and antioxidative activity. Life Sci 65: 197–206.
   PubMed Web of Science ®Google Scholar
• Sheu JR, Lee CR, Lin CC, Kan YC, Lin CH, Hung WC, Lee YM, Yen MH (1999b): The antiplatelet activity of PMC, a potent alpha-tocopherol analogue, is mediated through inhibition of cyclo-oxygenase. Br J Pharmacol 127: 1206–1212.
   PubMed Web of Science ®Google Scholar
• Suzuki YJ, Packer L (1993): Inhibition of NF-kappa B activation by vitamin E derivatives. Biochem Biophys Res Commun 193: 277–283.
   PubMed Web of Science ®Google Scholar
• Tafazoli S, Wright JS, O’Brien PJ (2005): Prooxidant and antioxidant activity of vitamin E analogues and troglitazone. Chem Res Toxicol 18: 1567–1574.
   PubMed Web of Science ®Google Scholar
• Yano K, Bauchat JR, Liimatta MB, Clemmons DR, Duan C (1999): Down-regulation of protein kinase C inhibits insulin-like growth factor I-induced vascular smooth muscle cell proliferation, migration, and gene expression. Endocrinology 140: 4622–4632.
   PubMedGoogle Scholar