3,255
Views
53
CrossRef citations to date
0
Altmetric
Research Article

Antidiabetic activity of alkaloids of Aerva lanata roots on streptozotocin-nicotinamide induced type-II diabetes in rats

, &
Pages 635-642 | Received 15 Apr 2012, Accepted 16 Dec 2012, Published online: 26 Mar 2013

References

  • Aiyer VN, Narayan V, Seshadri TR, Vydeeswaran S. (1973). Chemical components of some Indian medicinal plants. Indian J Chem 11:89–90
  • Appia KG, Rai VK, Nandy BC, et al. (2009). Hypoglycemic and antihyperlipidaemic effect of ethanol extract of aerial parts of Aerva lanata Linn. in normal and alloxan induced diabetic rats. IJPSDR 1:191–4
  • Babu PS, Prabuseenivasan S, Ignacimuthu S. (2007). Cinnamaldehyde – a potential antidiabetic agent. Phytomedicine 14:15–22
  • Bairwa NK, Sethiya NK, Mishra SH. (2010). Protective effect of stem bark of Ceiba pentandra Linn. against paracetamol-induced hepatotoxicity in rats. Phcog Res 2:26–30
  • Baltaev UA, Murdakhaev YM, Abubakirov NK. (1992). Phytoecdysteroids of Aerva lanata. Chem Nat Comp 28:123–4
  • Barik R, Jain S, Qwatra D, et al. (2008). Antidiabetic activity of aqueous root extract of Ichnocarpus frutescens in streptozotocin-nicotinamide induced type-II diabetes in rats. Indian J Pharmacol 40:19–22
  • Bell RH, Hye RJ. (1983). Animal models of diabetes mellitus: Physiology and pathology. J Surg Res 35:433–60
  • Bonner-Weir S. (1988). Morphological evidence of pancreatic polarity of beta cells within Islets of Langerhans. Diabetes 37:616–21
  • Chandra S, Sastry MS. (1990). Chemical constituents of Aerva lanata. Fitoterapia 61:188–90
  • Chowdhury D, Sayeed A, Islam A, et al. (2002). Antimicrobial activity and cytotoxicity of Aerva lanata. Fitoterapia 73:92–4
  • Deshmukh TA, Yadav BV, Badole SL, et al. (2008). Antihyperglycaemic activity of alcoholic extract of Aerva lanata (L.) A. L. Juss. Ex J. A. Schultes leaves in alloxan induced diabetic mice. J Appl Biomed 6:81–7
  • Eidi A, Eidi M, Esmaeili E. (2006). Antidiabetic effect of garlic (Allium sativum L.) in normal and streptozotocin-induced diabetic rats. Phytomedicine 13:624–9
  • Fan C, Yan J, Qian Y, et al. (2006). Regulation of lipoprotein lipase expression by effect of Hawthorn flavonoids on peroxisome proliferators response element pathway. J Pharmacol Sci 100:51–8
  • Fo ER, Fernandes JB, Vieira PC, da Silva MDDGF. (1992). Canthin-6-one alkaloids from Picrolemma granatensis. Phytochemistry 31:2499–501
  • Frode TS, Medeiros YS. (2008). Animal models to test drugs with potential antidiabetic activity. J Ethnopharmacol 115:173–83
  • Gebhardt R, Beck H. (1996). Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures. Lipids 31:1373–6
  • Gessler MC, Nkunya MH, Mwasumbi LB, et al. (1994). Screening Tanzanian medicinal plants for antimalarial activity. Acta Trop 56:65–77
  • Goyal M, Pareek A, Nagori BP, Sasmal D. (2011). Aerva lanata: A review on phytochemistry and pharmacological aspects. Phcog Rev 5:195–8
  • Kakrani HKN, Saluja AK. (1994). Traditional treatment through herbs in Kutch district, Gujarat state, India. Part II. Analgesic, anti-inflammatory, antirheumatic, antiarthritic plants. Fitoterapia 65:427–30
  • Kanchanapoom T, Kasai R, Chumsri P, et al. (2001). Canthin-6-one and β-carboline alkaloids from Eurycoma harmandiana. Phytochemistry 56:383–6
  • Majmudar FI, Shah MB, Patel KN, Shah BK. (1999). Aerva lanata – its diuretic and hepatoprotective activity. Indian J Nat Prod 15:9–12
  • Masiello P, Broca C, Gross R, et al. (1998). Experimental NIDDM: Development of a new model of type II diabetes in adult rats administered with streptozotocin and nicotinamide. Diabetes 47:224–9
  • Mehta A, Sethiya NK, Mehta C, Shah GB. (2011). Anti-arthritis activity of roots of Hemidesmus indicus R.Br. (Anantmul) in rats. Asian Pac J Trop Med 5:130–5
  • Mitsunaga K, Koike K, Tanaka T, et al. (1994). Canthin-6-one alkaloids from Eurycoma longifolia. Phytochemistry 35:799–802
  • Nagaraju N, Rao KN. (1990). A survey of plant crude drugs of rayalaseema, Andhra Pradesh, India. J Ethnopharmacol 29:137–58
  • Nevin KG, Vijayammal PL. (2005a). Effect of Aerva lanata against hepatotoxicity of carbon tetrachloride in rats. Environ Toxicol Pharmacol 20:471–7
  • Nevin KG, Vijayammal PL. (2005b). Pharmacological and immunomodulatory effects of Aerva lanata in Daltons lymphoma ascites-bearing mice. Pharm Biol 43:640–6
  • Noble RL. (1990). The discovery of the Vinca alkaloids – chemotherapeutic agents against cancer. Biochem Cell Biol 68:1344–51
  • OECD. (2000). Guidelines for the testing of chemicals. Guiding document on acute oral toxicity, environmental health and safety monograph series on testing and assessments
  • Rajesh R, Chitra K, Paarakh PM. (2011). Aerva lanata (Linn.) Juss. Ex Schult. An overview. Indian J Nat Prod Resour 2:5–9
  • Ram RL, Saha V. (1998). Ethnobotanical wealth of Ranchi District, Bihar II: Herbal medicinal plants used in dysentery. Bionature 18:13–5
  • Rerup CC. (1970). Drugs producing diabetes through damage of insulin secreting cells. Pharmacol Rev 22:485–518
  • Salahuddin M, Jalalpure SS. (2010). Antidiabetic activity of aqueous fruit extract of Cucumis trigonus Roxb. in streptozotocin-induced-diabetic rats. J Ethnopharmacol 127:565–7
  • Saravana KA, Kavimani S, Jayaveera KN. (2011). A review on medicinal plants with potential antidiabetic activity. Int J Phytopharmacol 2:53–60
  • Selvanayagam ZE, Gnanavendan SG, Balakrishnan K, Rao RB. (1994). Antisnake venom botanicals from ethnomedicine. J Herbs Spices Med Plants 2:45–100
  • Sethiya NK, Mishra SH. (2010). Review on ethanomedicinal uses and phyto-pharmacology of memory boosting herb Convolvulus pluricaulis Choisy. Aus J Med Herb 22:19–25
  • Sethiya NK, Nahata A, Mishra SH, Dixit VK. (2009). An update on shankhpushpi, a cognition-boosting Ayurvedic medicine. Zhong Xi Yi Jie He Xue Bao 7:1001–22
  • Sethiya NK, Nahata A, Dixit VK. (2010a). Anxiolytic activity of Canscora decussata in albino rats. J Compl Integ Med 7:1–12
  • Sethiya NK, Trivedi A, Patel MB, Mishra SH. (2010b). Comparative pharmacognostical investigation on four ethanobotanicals traditionally used as Shankhpushpi in India. J Adv Pharm Tech Res 1:392–9
  • Sethiya NK, Nahata A, Dixit VK, Mishra SH. (2012). Cognition boosting effect of Canscora decussata (a South Indian Shankhpushpi). Eur J Integr Med 4:113–21
  • Shah GL, Gopal GV. (1985). Some ethnomedical drugs used by the tribes of North Gujarat. J Econ Tax Bot 6:193–201
  • Sharma B, Satapathi SK, Roy P. (2007). Hypoglycemic and antihyperglycaemic effect of Aegel marmelos (L.) leaf extracts on streptozocin induced diabetic mice. Int J Pharmacol 3:444–52
  • Sharma B, Salunke R, Balomajumder C, et al. (2010). Anti-diabetic potential of alkaloid rich fraction from Capparis decidua on diabetic mice. J Ethnopharmacol 127:457–62
  • Shertzer HG, Schneider SN, Kendig EL, et al. (2009). Tetrahydroindenoindole inhibits the progression of diabetes in mice. Chem Biol Interact 15:71–80
  • Shirwaikar A, Rajendran K, Barik R. (2006). Effect of aqueous bark extract of Garuga pinnata Roxb. in streptozotocin–nicotinamide induced type-II diabetes mellitus. J Ethnopharmacol 107:285–90
  • Song Y, Chan CWY, Brown GM, et al. (1997). Studies of the renal action of melatonin: Evidence that the effects are mediated by 37kDa receptors of the Mel1a subtype localized primarily to the basolateral membrane of the proximal tubule. FASEB J 11:93–100
  • Soundararajan P, Mahesh R, Ramesh T, Begum VH. (2006). Effect of Aerva lanata on calcium oxalate urolitiasis in rats. Indian J Exp Biol 44:981–6
  • Sun B, Morikawa T, Matsuda H, et al. (2004). Structures of new beta-carboline-type alkaloids with antiallergic effects from Stellaria dichotoma. J Nat Prod 67:1464–9
  • Trivedi A, Sethiya NK, Mishra SH. (2011). Preliminary pharmacognostic and phytochemical analysis of “Granthika” (Leonotis nepetaefolia): An ayurvedic herb. Indian J Tradit Knowl 10:682–8
  • Vetrichelvan T, Jegadeesan M. (2002). Anti-diabetic activity of alcoholic extract of Aerva lanata (L.) Juss. ex Schultes in rats. J Ethnopharmacol 80:103–7
  • Vetrichelvan T, Jagadeesan M, Senthil PM, et al. (2000). Diuretic and anti-inflammatory activities of Aerva lanata in rats. Indian J Pharm Sci 62:300–2
  • Yamunadevi M, Wesely EG, Johnson MA. (2011a). Chemical profile studies on the alkaloids of medicinally important plant Aerva lanata L. using HPTLC. J Natura Conscientia 2:341–9
  • Yamunadevi M, Wesely EG, Johnson MA. (2011b). Chromatographic fingerprint analysis on flavonoids constituents of the medicinally important plant Aerva lanata L. by HPTLC technique. Asian Pac J Trop Biomed 1:8–12
  • Yamunadevi M, Wesely EG, Johnson MA. (2011c). Chromatographic finger print analysis of steroids in Aerva lanata L by HPTLC technique. Asian Pac J Trop Biomed 1:428–33
  • Yasin SA, Grossman A, Forsling ML. (1996). Diurnal variation in the effect of melatonin on neurohypophysial hormone release from the rat hypothalamus. Brain Res Bul 39:1–5
  • Yuldashev AA, Yuldashev MP, Abdullabekova VN. (2002). Components of Aerva lanata. Chem Nat Comp 38:293–4
  • Zapesochnaya GG, Kurkin VA, Pervykh LN. (1990). A study of the herb Aerva lanata II. Feruloylamines. Chem Nat Comp 26:590–1
  • Zapesochnaya GG, Pervykh LN, Kurkin VA, et al. (1991). A study of the herb Aerva lanata III- Alkaloids. Chem Nat Comp 27:336–40
  • Zapesochnaya G, Kurkin V, Okhanov V, Miroshnikov A. (1992a). Canthin-6-one and beta-carboline alkaloids from Aerva lanata. Planta Med 58:192–6
  • Zapesochnaya GG, Kurkin VA, Okhanov VV, et al. (1992b). The structure of the alkaloids of Aerva lanata. Chem Nat Comp 27:725–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.