Osthole induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells

References

• Andrew M. (1995). Cycling ubiquitination: The destructive end of mitosis. Cell 81:149–52
   PubMedGoogle Scholar
• Antonsson B, Martinou JC. (2000). The Bcl-2 protein family. Exp Cell Res 256:50–7
   PubMed Web of Science ®Google Scholar
• Blagosklonny MV. (2003). Targeting cancer cells by exploiting their resistance. Trends Mol Med 9:307–12
   PubMed Web of Science ®Google Scholar
• Brune B, Kneten VA, Sandau K. (1998). Nitric oxide and its role in apoptosis. Eur J Pharmacol 35:261–72
   Google Scholar
• Chen CN, Wu CL, Lin JK. (2007). Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis. Cancer Lett 245:218–31
   PubMed Web of Science ®Google Scholar
• Cheng YL, Chang WL, Lee SC, et al. (2003). Acetone extract of Bupleurum scorzonerifolium inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing telomerase activity. Life Sci 73:2383–94
   PubMed Web of Science ®Google Scholar
• Chou SY, Hsu HC, Wang KT, et al. (2007). Antitumor effects of osthole from Cnidium monnieri: An in vitro and in vivo study. Phytother Res 21:226–30
   PubMed Web of Science ®Google Scholar
• Cohen GM. (1997). Caspases: The executioners of apoptosis. J Biochem 326:1–16
   Google Scholar
• Fulda S, Debatin KM. (2006). Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25:4798–811
   PubMed Web of Science ®Google Scholar
• Ghobrial IM, Witzig TE, Adjei AA. (2005). Targeting apoptosis pathways in cancer therapy. CA Cancer J Clin 55:178–94
   PubMed Web of Science ®Google Scholar
• Han SI, Kim YS, Kim TH. (2008). Role of apoptotic and necrotic cell death under physiologic conditions. BMB Rep 41:1–10
   PubMed Web of Science ®Google Scholar
• Harada H, Grant S. (2003). Apoptosis regulators. Rev Clin Exp Hematol 7:117–38
   PubMedGoogle Scholar
• Levites Y, Youdim MBH, Maor G, Mandel S. (2002). Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappa B (NF-kappa B) activation and cell death by tea extracts in neuronal cultures. Biochem Pharmacol 63:21–9
   PubMed Web of Science ®Google Scholar
• Liang HJ, Suk FM, Wang CK, et al. (2009). Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db/db mice. Chem Biol Interact 181:309–15
   PubMed Web of Science ®Google Scholar
• Mao XX, Yin Wei, Liu MF, et al. (2011). Osthole, a natural coumarin, improves neurobehavioral functions and reduces infarct volume and matrix metalloproteinase-9 activity after transient focal cerebral ischemia in rats. Brain Res 1385:275–80
   PubMed Web of Science ®Google Scholar
• Okamoto T, Kobayashi T, Yoshida S. (2005). Chemical aspects of coumarin compounds for the prevention of hepatocellular carcinomas. Curr Med Chem Anticancer Agents 5:47–51
   PubMedGoogle Scholar
• Okamoto T, Kobayashi T, Yoshida S. (2007). Synthetic derivatives of osthole for the prevention of hepatitis. Med Chem 3:35–44
   PubMed Web of Science ®Google Scholar
• Reed JC. (1997). Double identity for proteins of the Bcl-2 family. Nature 387:773–6
   PubMed Web of Science ®Google Scholar
• Renmin L, Lei F, Ailing S, Lingyi K. (2004). Preparative isolation and purification of coumarins from Cnidium monnieri (L.) Cusson by high-speed counter-current chromatography. J Chromatogr A 1055:71–6
   PubMed Web of Science ®Google Scholar
• Reyes-Zurita FJ, Rufino-Palomares EE, Lupianez JA, Cascante M. (2009). Maslinic acid, a natural triterpene from Olea europaea (L.), induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway. Cancer Lett 273:44–54
   PubMed Web of Science ®Google Scholar
• Riviere C, Goossens L, Pommery N, et al. (2006). Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker. Nat Prod Res 20:909–16
   PubMed Web of Science ®Google Scholar
• Rodriguez-Nieto S, Zhivotovsky B. (2006). Role of alterations in the apoptotic machinery in sensitivity of cancer cells to treatment. Cur Phar Des 12:4411–25
   PubMed Web of Science ®Google Scholar
• Tang CH, Yang RS, Chien M, et al. (2008). Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts. Eur J Pharmacol 579:40–9
   PubMed Web of Science ®Google Scholar
• Wang Y, Che CM, Chiu FQ, He Y. (2007). Dioscin (saponin)-induced generation of reactive oxygen species through mitochondria dysfunction: A proteomic-based study. J Proteome Res 6:4703–10
   PubMed Web of Science ®Google Scholar
• Xu XM, Zhang Y, Qu D, et al. (2011). Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway. J Exp Clin Canc Res 30:33–8
   PubMed Web of Science ®Google Scholar
• Yang L, Wu D, Luo K, et al. (2009). Andrographolide enhances 5-fluorouracil-induced apoptosis via caspase-8-dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma (SMMC-7721) cells. Cancer Lett 276:180–8
   PubMed Web of Science ®Google Scholar
• Yang LL, Wang M, Chen LG, Wang CC. (2003). Cytotoxic activity of coumarins from the fruits of Cnidium monnieri on leukemia cell lines. Planta Med 69:1091–5
   PubMed Web of Science ®Google Scholar
• You L, Feng S, An R, Wang X. (2009). Osthole: A promising lead compound for drug discovery from a traditional Chinese medicine (TCM). Nat Prod Commun 4:297–302
   PubMedGoogle Scholar
• Zhang J, Shen YL, Liu JW, Wei DZ. (2005). Antimetastatic effect of prodigiosin through inhibition of tumor invasion. Biochem Pharmacol 69:407–14
   PubMedGoogle Scholar
• Zimecki M, Artym J, Cisowski W, et al. (2009). Immunomodulatory and anti-inflammatory activity of selected osthole derivatives. Naturforsch C 64:361–8
   PubMedGoogle Scholar
• Zimmermann KC, Bonzon C, Green D. (2001). The machinery of programmed cell death. Pharmacol Therapeut 92:57–70
   PubMed Web of Science ®Google Scholar