References
- Aho TLT, Sandholm J, Peltola KJ, et al. (2004). Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Serl 12 gatekeeper site. FEBS Lett 571:43–9
- Allen JD, Verhoeven E, Domen J, et al. (1997). Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc. Oncogene 15:1133–41
- Amaravadi R, Thompson CB. (2005). The survival kinases Akt and Pim as potential pharmacological targets. J Clin Invest 115:2618–24
- Bachmann M, Moroy T. (2005). The serine/threonine kinase Pim-1. Int J Biochem Cell Biol 37:726–30
- Cibull TL, Jones TD, Li L, et al. (2006). Overexpression of Pim-1 during progression of prostatic adenocarcinoma. J Clin Pathol 59:285–8
- Dai H, Li R, Wheeler T, et al. (2005). Pim-2 upregulation: Biological implications associated with disease progression and perinueral invasion in prostate cancer. Prostate 65:276–86
- Eichmann A, Yuan L, Breant C, et al. (2000). Developmental expression of pim kinases suggests functions also outside of the hematopoietic system. Oncogene 19:1215–24
- Geromichalos GD. (2007). Importance of molecular computer modeling in anticancer drug development. J BUON 1:S101–18
- Li YY, Popivanova BK, Nagai Y, et al. (2006). Pim-3, a proto-oncogene with serin/theronine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines. Cancer Res 66:6741–7
- Morishita D, Katayama R, Sekimizu K, et al. (2008). Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27KipI at the transcriptional and posttranscriptional levels. Cancer Res 68:5076–85
- Morishita D, Takami M, Yoshikawa S, et al. (2011). Cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase. J Biol Chem 286:2681–8
- Nawijn MC, Alendar A, Berns A. (2011). For better or for worse: The role of Pim oncogenes in tumorigenesis. Nat Rav Cancer 11:23–34
- Popivanova BK, Li YY, Zheng H, et al. (2007). Proto-oncogenes, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in colon cancer cells and can prevent Bad-mediated apoptosis. Cancer Sci 98:321–8
- Siu A, Virtanen C, Jongstra J. (2011). Pim kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer. Oncotarget 2:1134–44
- Wadood A, Riaz M, Jamal SB, et al. (2013). Molecular docking study of P4-benzoxaborole substituted ligands as inhibitors of HCV NS3/4A protease. Bioinformation 9:309–14
- Wu Y, Wang YY, Nakamota Y, et al. (2010). Accelerated hepatocellular carcinoma development in mice expression the Pim-3 transgene selectively in the liver. Oncogene 29:2228–37
- Xiang Y, Hirth B, Asmussen G, et al. (2011). The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorg Med Chem Lett 21:3050–6