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Original Article

Beneficial effects of melatonin on serum nitric oxide, homocysteine, and ADMA levels in fructose-fed rats

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Pages 1035-1041 | Received 02 Apr 2014, Accepted 03 Aug 2014, Published online: 22 Jan 2015

References

  • Araki A, Sako Y. (1987). Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 422:43–52
  • Assumpçao CR, Brunini TMC, Matsuura C, Mendes-Riberio AC. (2008). Impact of the l-arginine-nitric oxide pathway and oxidative stress on the pathogenesis of the metabolic syndrome. Open Biochem J 2:108–15
  • Bestermann WH. (2011). The ADMA–metformin hypothesis: Linking the cardiovascular consequences of the metabolic syndrome and type II diabetes. Cardiorenal Med 1:211–19
  • Bezerra RM, Ueno M, Silva MS, et al. (2000). A high fructose diet affects the early steps of insulin action in muscle and liver of rats. J Nutr 130:1531–5
  • Cardinali DP, Bernasconi PA, Reynoso R, et al. (2013). Melatonin may curtail the metabolic syndrome: Studies on initial and fully established fructose-induced metabolic syndrome in rats. Int J Mol Sci 14:2502–14
  • Castro MC, Massa ML, Schinella G, et al. (2013). Lipoic acid prevents liver metabolic changes induced by administration of a fructose-rich diet. Biochim Biophys Acta 1830:2226–32
  • Chan TY, Tang PL. (1995). Effect of melatonin on the maintenance of cholesterol homeostasis in the rat. Endocr Res 21:681–96
  • Chen BM, Xia LW, Zhao RQ. (1997). Determination of N(G),N(G)-dimethylarginine in human plasma by high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl 692:467–71
  • Dai S, McNeill JH. (1995). Fructose-induced hypertension in rats is concentration and duration dependent. J Pharmacol Toxicol Methods 33:101–7
  • Dayal S, Lentz SR. (2005). ADMA and hyperhomocysteinemia. Vasc Med 10:S27–33
  • Dayal S, Arning E, Bottiglieri T, et al. (2004). Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice. Stroke 35:1957–62
  • de Moura RF, Ribeiro C, de Oliveira JA, et al. (2009). Metabolic syndrome signs in Wistar rats submitted to different high fructose ingestion protocols. Br J Nutr 101:1178–84
  • Delbosc S, Paizanis E, Magous R, et al. (2005). Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat. Atherosclerosis 179:43–9
  • Elliott SS, Keim NL, Stern JS, et al. (2002). Fructose, weight gain, and the insulin resistance syndrome. Am J Clin Nutr 76:911–22
  • Ersahin M, Sehirli O, Toklu HZ, et al. (2009). Melatonin improves cardiovascular function and ameliorates renal, cardiac and cerebral damage in rats with renovascular hypertension. J Pineal Res 47:97–106
  • Giani JF, Mayer MA, Munoz MC, et al. (2009). Chronic infusion of angiotensin-(1–7) improves insulin resistance and hypertension induced by a high-fructose diet in rats. Am J Physiol Endocrinol Metab 296:E262–71
  • Glushakova O, Kosugi T, Roncal C, et al. (2008). Fructose induces the inflammatory molecule ICAM-1 in endothelial cells. J Am Soc Nephrol 19:1712–20
  • Hanson RL, Imperatore G, Bennett PH, Knowler WC. (2002). Components of the metabolic syndrome and incidence of type 2 diabetes. Diabetes 51:3120–7
  • Johnson RJ, Segal MS, Sautin Y, et al. (2007). Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease and cardiovascular disease. Am J Clin Nutr 86:899–906
  • Kamata K, Yamashita K. (1999). Insulin resistance and impaired endothelium-dependent renal vasodilatation in fructose-fed hypertensive rats. Res Commun Mol Pathol Pharmacol 103:195–210
  • Kim EH, Koh EH, Park JY, Lee KU. (2010). Adenine nucleotide translocator as a regulator of mitochondrial function: Implication in the pathogenesis of metabolic syndrome. Korean Diabetes J 34:146–53
  • Kitagava A, Ohta Y, Ohashi K. (2012). Melatonin improves metabolic syndrome induced by high fructose intake in rats. J Pineal Res 52:403–13
  • Kozirog M, Poliwczak AR, Duchnowicz P, et al. (2011). Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome. J Pineal Res 50:261–6
  • Leibowitz A, Peleg E, Sharabi Y, et al. (2008). The role of melatonin in the pathogenesis of hypertension in rats with metabolic syndrome. Am J Hypertens 21:348–51
  • Marchesi C, Ebrahimian T, Angulo O, et al. (2009). Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome. Hypertension 54:1384–92
  • Miatello R, Vazguez M, Renna N, et al. (2005). Chronic administration of resveratrol prevent biochemical cardiovascular changes in fructose-fed rats. Am J Hypertens 18:864–70
  • Miller A, Adeli K. (2008). Dietary fructose and the metabolic syndrome. Curr Opin Gastroenterol 24:204–9
  • Muhlbauer E, Albrecht E, Bazwinsky-Wutschke I, Peschke E. (2012). Melatonin influences insulin secretion primarily via MT1 receptors in rat insulinoma cells (INS-1) and mouse pancreatic islets. J Pineal Res 52:446–59
  • Murawska-Cialowicz E, Januszewska L, Zuwala-Jagiello J, et al. (2008). Melatonin decreases homocysteine level in blood of rats. J Physiol Pharmacol 59:717–29
  • Nduhirabandi F, du Toit EF, Lochner A. (2012). Melatonin and the metabolic syndrome: A tool for effective therapy in obesity-associated abnormalities? Acta Physiol 205:209–23
  • Okatani Y, Wakatsuki A, Reiter RJ. (2000). Protective effect of melatonin against homocysteine-induced vasoconstriction of human umbilical artery. Biochem Biophys Res Commun 277:470–5
  • Okatani Y, Wakatsuki A, Reiter RJ. (2001). Melatonin suppresses homocysteine enhancement of serotonin-induced vasoconstriction in the human umbilical artery. J Pineal Res 31:242–7
  • Reddy SS, Ramatholisamma P, Karuna R, Saralakumari D. (2009). Preventive effect of Tinospora cordifolia against high-fructose diet-induced insulin resistance and oxidative stress in male Wistar rats. Food Chem Toxicol 47:2224–9
  • Rios-Lugo MJ, Cano P, Jimenez-Ortega V, et al. (2010). Melatonin effect on plasma adiponectin, leptin, insulin, glucose, triglycerides and cholesterol in normal and high fat-fed rats. J Pineal Res 49:342–8
  • Robeva R, Kirilov G, Tomova A, Kumanov P. (2008). Melatonin-insulin interactions in patients with metabolic syndrome. J Pineal Res 44:52–6
  • Sanchez-Lozada LG, Tapia E, Jimenez A, et al. (2007). Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol 292:F423–9
  • Sartori C, Dessen P, Mathieu C, et al. (2009). Melatonin improves glucose homeostasis and endothelial vascular function in high-fat diet-fed insulin-resistant mice. Endocrinology 150:5311–17
  • Scherrer U, Randin D, Vollenweider P, et al. (1994). Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest 94:2511–15
  • Srinivasan V, Ohta Y, Espino J, et al. (2013). Metabolic syndrome, its pathophysiology and the role of melatonin. Recent Pat Endocr Metab Immun Drug Discov 7:11–25
  • Stühlinger MC, Tsao PS, Her JH, et al. (2001). Homocysteine impairs the nitric oxide synthase pathway: Role of asymmetric dimethylarginine. Circulation 104:2569–75
  • Sydow K, Münzel T. (2003). ADMA and oxidative stress. Atherosclerosis Suppl 4:41–51
  • Tain YL, Hsieh CS, Chen CC, et al. (2010a). Melatonin prevents increased asymmetric dimethylarginine in young rats with bile duct ligation. J Pineal Res 48:212–21
  • Tain YL, Huang LT, Lin IC, et al. (2010b). Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. J Pineal Res 49:390–8
  • Tain YL, Kao YH, Hsieh CS, et al. (2010c). Melatonin blocks oxidative stress-induced increased asymmetric dimethylarginine. Free Radic Biol Med 49:1088–98
  • Tran LT, Yuen VG, McNeill JH. (2009). The fructose-fed rat: A review on the mechanisms of fructose-induced insulin resistance and hypertension. Mol Cell Biochem 332:145–59
  • Verma S, Skarsgard P, Bhanot S. (1997). Reactivity of mesenteric arteries from fructose hypertensive rats to endothelin-1. Am J Hypertens 10:1010–19
  • Wilcken DE, Wang J, Sim AS, et al. (2006). Asymmetric dimethylarginine in homocystinuria due to cystathionine beta-synthase deficiency: Relevance of renal function. J Inherit Metab Dis 29:30–7
  • Zanuto R, Siqueira-Filho MA, Caperuto LC, et al. (2013). Melatonin improves insulin sensitivity independently of weight loss in old obese rats. J Pineal Res 55:156–65

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