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Original Article

Protective effects of the standardized extract of Zingiber officinale on myocardium against isoproterenol-induced biochemical and histopathological alterations in rats

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Pages 1795-1802 | Received 09 Oct 2014, Accepted 11 Jan 2015, Published online: 05 May 2015

References

  • Ahmed RS, Seth V, Banerjee BD. (2000a). Influence of dietary ginger (Zingiber officinale Rosc.) on antioxidant defense system in rat: Comparison with ascorbic acid. Indian J Exp Biol 38:604–6
  • Ahmed RS, Seth V, Pasha ST, Banerjee BD. (2000b). Influence of dietary ginger (Zingiber officinale Rosc) on oxidative stress induced by malathion in rats. Food Chem Toxicol 38:443–50
  • Apple FS, Murakami MM. (2005). Cardiac troponin and creatine kinase MB monitoring during in-hospital myocardial reinfarction. Clin Chem 51:460–3
  • Arya DS, Bansal P, Ojha SK, et al. (2006). Pyruvate provides cardioprotection in the experimental model of myocardial ischemia reperfusion injury. Life Sci 79:38–44
  • Center for Drug Evaluation and Research (CDER), Food and Drug Administration, U.S. Department of Health and Human Services. (2005). Guidance for Industry: Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers. Rockville, USA
  • De Bono DP, Boon NA. (1992). Diseases of the cardiovascular system. In: Edwards CRW, Bouchier IAS, eds. Davidson’s Principles of Practice and Medicine, Hong Kong: Churchill Livingstone, 249–340
  • Dugasani S, Pichika MR, Nadarajah VD, et al. (2010). Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol. J Ethnopharmacol 127:515–20
  • Fuhrman B, Rosenblat M, Hayek T, et al. (2000). Ginger extract consumption reduces plasma cholesterol, inhibits LDL oxidation and attenuates development of atherosclerosis in atherosclerotic, apolipoprotein E-deficient mice. J Nutr 130:1124–31
  • Hegstad AC, Ytrehus K, Myklebust R, Jorgensen L. (1994). Ultrastructural changes in myocardial myocytic mitochondria: Crucial step in the development of oxygen radical induced damage in isolated rat hearts. Basic Res Cardiol 89:128–38
  • Hill MF, Singal PK. (1996). Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats. Am J Pathol 148:291–300
  • International Conference on the Harmonization of Technical Requirements for the Registration of Pharmaceuticals for Human Use. (ICH) (2005). ICH harmonized tripartite guideline validation of analytical procedures: Text and methodology Q2 (R1). Current Step 4 version, Parent Guideline dated 27 October 1994 (Complementary Guideline on Methodology dated 6 November 1996 incorporated in November 2005)
  • Ippoushi K, Azuma K, Ito H, et al. (2003). [6]-Gingerol inhibits nitric oxide synthesis in activated J774.1 mouse macrophages and prevents peroxynitrite-induced oxidation and nitration reactions. Life Sci 73:3427–37
  • Jaffe AS, Babuin L, Apple FS. (2006). Biomarkers in acute cardiac disease. J Am Coll Cardiol 48:1–11
  • Jaffe AS, Ravkilde J, Roberts R. (2000). It’s time for a change to a troponin standard. Circulation 102:1216–20
  • Jolad SD, Lantz RC, Solyon AM, et al. (2004). Fresh organically grown ginger (Zingiber officinale): Composition and effects on LPS-induced PGE2 production. Phytochemistry 65:1937–54
  • Koo KL, Ammit AJ, Tran VH, et al. (2001). Gingerols and related analogues inhibit arachidonic acid-induced human platelet serotonin release and aggregation. Thromb Res 103:387–97
  • Kota N, Krishna P, Polasa K. (2008). Alterations in antioxidant status of rats following intake of ginger through diet. Food Chem 106:991–6
  • Kundu J, Surh YJ. (2009). Molecular basis of chemoprevention with dietary phytochemicals: Redox-regulated transcription factors as relevant targets. Phytochem Rev 8:333–47
  • Mallikarjuna K, Chetan PS, Reddy KS, Rajendra W. (2008). Ethanol toxicity: Rehabilitation of hepatic antioxidant defense system with dietary ginger. Fitoterapia 79:174–8
  • Masuda Y, Kikuzaki H, Hisamoto M, Nakatani N. (2004). Antioxidant properties of gingerol related compounds from ginger. Biofactors 21:293–6
  • Mathers CD, Loncar D. (2006). Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3:2011–30
  • NSF International (2012). HPLC Analysis of Gingerols and Shogaols in Zingiber officinale (Ginger) INA Method 114.000. Available from: http://www.nsf.org/business/ina/ginger.asp?program = INA [last accessed 3 Apr 2012]
  • Oka JM, Simic DV, Simic TP. (1996). Free radicals in cardiovascular disease. Sci J Facta Universitatis 6:11–12
  • Panteghini M, Apple FF, Christenson RH, et al. (1999). Proposals from the IFCC Committee on markers of cardiac damage (C-SMCD): Recommendations on the use of biochemical markers of cardiac damage in acute coronary syndromes. Scan J Clin Lab Invest 59:103–12
  • Rajadurai M, Prince PSM. (2006). Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: Biochemical and histopathological evidences. Toxicology 228:259–68
  • Rathore N, John S, Kale M, Bhatnagar D. (1998). Lipid peroxidation and antioxidant enzymes in isoproterenol induced oxidative stress in rat tissues. Pharmacol Res 38:297–303
  • Sabeena FKH, Anandan R, Kumar SH, et al. (2004). Effect of squalene on tissue defense system in isoproterenol-induced myocardial infarction in rats. Pharmacol Res 50:231–6
  • Saputri FC, Jantan I. (2011). Effects of selected medicinal plants on human low-density lipoprotein oxidation, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and human platelet aggregation. J Med Plants Res 5:6182–99
  • Sawyer DB, Siwik DA, Xiao L, et al. (2002). Role of oxidative stress in myocardial hypertrophy and failure. J Mol Cell Cardiol 34:379–88
  • Shanmugam KR, Mallikarjuna K, Nishanth K, et al. (2011). Protective effect of dietary ginger on antioxidant enzymes and oxidative damage in experimental diabetic rat tissues. Food Chem 124:1436–42
  • Shukla Y, Singh M. (2007). Cancer preventive properties of ginger: A brief review. Food Chem Toxicol 45:683–90
  • Singal PK, Beamish RE, Dhalla NS. (1983). Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease. Adv Exp Med Biol 161:391–440
  • Srivastava KC, Mustafa T. (1989). Spices: Antiplatelet activity and prostanoid metabolism. Prostaglandins Leukot Essent Fatty Acids 38:255–66
  • Suekawa M, Ishige A, Yuasa K, et al. (1984). Pharmacological studies on ginger. I. Pharmacological actions of pungent constituents, (6)-gingerol and (6)-shogaol. J Pharmacobiodyn 7:836–48
  • Thomson M, Al-Qattan KK, Al-Sawan SM, et al. (2002). The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. Prostaglandin Leukot Essent Fatty Acids 67:475–8
  • Thygesen K, Alpert JS, White HD. (2007). Universal definition of myocardial infarction. J Am Coll Cardiol 60:2173–95
  • Wexler BC, Greenberg BP. (1978). Protective effect of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. Atherosclerosis 29:373–5
  • Wexler BC. (1978). Myocardial infarction in young vs old male rats; pathophysiologic changes. Am Heart J 96:70–80
  • World Health Organization (WHO) (2011). Global Atlas on Cardiovascular Disease Prevention and Control. Geneva: WHO

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