1,490
Views
15
CrossRef citations to date
0
Altmetric
Original Article

1β-Hydroxyalantolactone, a sesquiterpene lactone from Inula japonica, attenuates atopic dermatitis-like skin lesions induced by 2,4-dinitrochlorobenzene in the mouse

, , , , &
Pages 516-522 | Received 27 Feb 2015, Accepted 10 May 2015, Published online: 28 May 2015

References

  • Choi JH, Park YN, Li Y, et al. (2010). Flowers of Inula japonica attenuate inflammatory responses. Immune Netw 10:145–52
  • Garcia-Pineres AJ, Castro V, Mora G, et al. (2001). Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones. J Biol Chem 276:39713–20
  • Giordano OS, Pestchanker MJ, Guerreiro E, et al. (1992). Structure–activity relationship in the gastric cytoprotective effect of several sesquiterpene lactones. J Med Chem 35:2452–8
  • Gottlieb AB. (2005). Therapeutic options in the treatment of psoriasis and atopic dermatitis. J Am Acad Dermatol 53:S3–16
  • Hall IH, Starnes CO, Lee KH, et al. (1980). Mode of action of sesquiterpene lactones as anti-inflammatory agents. J Pharm Sci 69:537–43
  • Heinrich M, Robles M, West JE, et al. (1998). Ethnopharmacology of Mexican Asteraceae (Compositae). Annu Rev Pharmacol Toxicol 38:539–65
  • Homey B, Steinhoff M, Ruzicka T, et al. (2006). Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 118:178–89
  • Jin H, He R, Oyoshi M, et al. (2009). Animal models of atopic dermatitis. J Invest Dermatol 129:31–40
  • Kehren J, Desvignes C, Krasteva M, et al. (1999). Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity. J Exp Med 189:779–86
  • Koch E, Klaas CA, Rungeler P, et al. (2001). Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-kappaB. Biochem Pharmacol 62:795–801
  • Kwok BH, Koh B, Ndubuisi MI, et al. (2001). The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chem Biol 8:759–66
  • Larsen JM, Geisler C, Nielsen MW, et al. (2007). Cellular dynamics in the draining lymph nodes during sensitization and elicitation phases of contact hypersensitivity. Contact Dermatitis 57:300–8
  • Leung D. (1993). Role of IgE in atopic dermatitis. Curr Opin Immunol 5:956–62
  • Leung DY, Bieber T. (2003). Atopic dermatitis. Lancet 361:151–60
  • Leung DY, Hirsch RL, Schneider L, et al. (1990). Thymopentin therapy reduces the clinical severity of atopic dermatitis. J Allergy Clin Immunol 85:927–33
  • Li Y-M, Li X-R. (2009). Effects of Qingshi Cream on chronic dermatitis-eczema in mice. J Chin Integr Med 7:1164–6
  • Man MQ, Hatano Y, Lee SH, et al. (2008). Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: Structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. J Invest Dermatol 128:79–86
  • Matsumoto K, Mizukoshi K, Oyobikawa M, et al. (2004). Establishment of an atopic dermatitis-like skin model in a hairless mouse by repeated elicitation of contact hypersensitivity that enables to conduct functional analyses of the stratum corneum with various non-invasive biophysical instruments. Skin Res Technol 10:122–9
  • Merfort I. (2011). Perspectives on sesquiterpene lactones in inflammation and cancer. Curr Drug Targets 12:1560–73
  • Novak N. (2009). New insights into the mechanism and management of allergic diseases: Atopic dermatitis. Allergy 64:265–75
  • Park YN, Lee YJ, Choi JH, et al. (2011). Alleviation of OVA-induced airway inflammation by flowers of Inula japonica in a murine model of asthma. Biosci Biotechnol Biochem 75:871–6
  • Pastore S, Mascia F, Girolomoni G. (2006). The contribution of keratinocytes to the pathogenesis of atopic dermatitis. Eur J Dermatol 16:125–31
  • Qin J-J, Jin H-Z, Zhu J-X, et al. (2010). New sesquiterpenes from Inula japonica Thunb. with their inhibitory activities against LPS-induced NO production in RAW264.7 macrophages. Tetrahedron 66:9379–88
  • Rosso JD, Friedlander SF. (2005). Corticosteroids: Options in the era of steroid-sparing therapy. J Am Acad Dermatol 53:S50–8
  • Schinella GR, Giner RM, Recio MC, et al. (1998). Anti-inflammatory effects of South American Tanacetum vulgare. J Pharm Pharmacol 50:1069–74
  • Wang B, Fujisawa H, Zhuang L, et al. (2000). CD4+ Th1 and CD8+ type 1 cytotoxic T cells both play a crucial role in the full development of contact hypersensitivity. J Immunol 165:6783–90
  • Wendel GH, Maria AO, Mohamed F, et al. (1999). Effect of dehydroleucodine in experimental colitis in rats and mice. Pharmacol Res 40:339–44
  • Wood LC, Jackson SM, Elias PM, et al. (1992). Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Clin Invest 90:482–7
  • Yamanaka K, Mizutani H. (2011). The role of cytokines/chemokines in the pathogenesis of atopic dermatitis. Curr Probl Dermatol 41:80–92

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.