Curcumin induced apoptosis via PI3K/Akt-signalling pathways in SKOV3 cells

Reference

• Ahmed N, Adhami VM, Afaq F, Feyes DK, Mukhtar H. 2001. Resveratrol causes WAF-1/p21-mediatedG(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells. Clin Cancer Res. 7:1466–1473.
   PubMed Web of Science ®Google Scholar
• Arafa el- SA, Zhu Q, Barakat BM, Wani G, Zhao Q, El-Mahdy MA, Wani AA. 2009. Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway. Cancer Res. 69:8910–8917.
   PubMed Web of Science ®Google Scholar
• Benchoua A, Guegan C, Couriaud C, Hosseini H, Sampao N, Morin D, Onténiente B. 2001. Specific caspase pathways are activated in the two stages of cerebral infarction. J Neurosci. 21:7127–7134.
   PubMed Web of Science ®Google Scholar
• Bradshaw TD, Stone EL, Trapani V, Leong C-O, Matthews CS, te Poele R, Stevens MFG. 2008. Mechanisms of acquired resistance to 2-(4-amino-3-methylphenyl)benzothiazole in breast cancer cell lines. Breast Cancer Res Treat. 110:57–68.
   PubMed Web of Science ®Google Scholar
• Chen J, Nagayama T, Jin K, Stetler RA, Zhu RL, Graham SH, Simon RP. 1998. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J Neurosci. 18:4914–4928.
   PubMed Web of Science ®Google Scholar
• Ferrer I, Planas AM. 2003. Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra. J Neuropathol Exp Neurol. 62:329–339.
   PubMed Web of Science ®Google Scholar
• Fruman DA, Cantley LC. 2002. Phosphoinositide 3-kinase in immunological systems. Semin Immunol. 14:7–18.
   PubMed Web of Science ®Google Scholar
• Kermorgant S, Aparicio T, Dessirier V, Lewin MJM, Lehy T. 2001. Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvement. Carcinogenesis. 22:1035–1042.
   PubMed Web of Science ®Google Scholar
• Kluza J, Lansiaux A, Wattez N, Mahieu C, Osheroff N, Bailly C. 2000. Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103. Cancer Res. 60:4077–4084.
   PubMed Web of Science ®Google Scholar
• Kritikou I, Giannopoulou E, Koutras AK, Labropoulou VT, Kalofonos HP. 2014. The combination of antitumor drugs, exemestane and erlotinib, induced resistance mechanism in H358 and A549 non-small cell lung cancer (NSCLC) cell lines. Pharm Biol. 52:444–452.
   Web of Science ®Google Scholar
• Kuo PL, Hsu YL, Cho CY. 2006. Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells. Mol Cancer Ther. 5:3209–3221.
   PubMed Web of Science ®Google Scholar
• Luo J, Manning BD, Cantley LC. 2003. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell. 4:257–262.
   PubMed Web of Science ®Google Scholar
• Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. 2006. Multiple biological activities of curcumin: a short review. Life Sci. 78:2081–2087.
   PubMed Web of Science ®Google Scholar
• Manabat C, Han BH, Wendland M, Derugin N, Fox CK, Choi J, Holtzman DM, Ferriero DM, Vexler ZS. 2003. Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain. Stroke. 34:207–213.
   PubMed Web of Science ®Google Scholar
• Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 65:55–63.
   PubMed Web of Science ®Google Scholar
• Murugan AC, Karim MR, Yusoff MBM, Tan SH, Asras MF, Rashid SS. 2015. New insights into seaweed polyphenols on glucose homeostasis. Pharm Biol. 53:1087–1097.
   PubMed Web of Science ®Google Scholar
• Nicoletti I. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods. 132:272–279.
   Google Scholar
• Polster BM, Fiskum G. 2004. Mitochondrial mechanisms of neural cell apoptosis. J Neurochem. 90:1281–1289.
   PubMed Web of Science ®Google Scholar
• Ravindran J, Prasad S, Aggarwal BB. 2009. Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J. 11:495–510.
   PubMed Web of Science ®Google Scholar
• Rosse T, Olivier R, Monney L, Rager M, Conus S, Fellay I, Jansen B, Borner C. 1998. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature. 391:496–499.
   PubMed Web of Science ®Google Scholar
• Salakou S, Kardamakis D, Tsamandas AC, Zolota V, Apostolakis E, Tzelepi V, Papathanasopoulos P, Bonikos DS, Papapetropoulos T, Petsas T, et al. 2007. Increased Bax/Bcl-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis in vivo. In Vivo. 21:123–132.
   PubMed Web of Science ®Google Scholar
• Sharma RA, Gescher AJ, Steward WP. 2005. Curcumin: the story so far. Eur J Cancer. 41:1955–1968.
   PubMed Web of Science ®Google Scholar
• Sharp FR, Lu A, Tang Y, Millhorn DE. 2000. Multiple molecular penumbras after focal cerebral ischemia. J Cereb Blood Flow Metab. 20:1011–1032.
   PubMed Web of Science ®Google Scholar
• Wallin JJ, Guan J, Prior WW, Edgar KA, Kassees R, Sampath D, Belvin M, Friedman LS. 2010. Nuclear phospho-Akt increase predicts synergy of PI3K inhibition and doxorubicin in breast and ovarian cancer. Sci Transl Med. 2:48–66.
   Web of Science ®Google Scholar
• Yamori T, Matsunaga A, Sato S, Yamazaki K, Komi A, Ishizu K, Mita I, Edatsugi H, Matsuba Y, Takezawa K, et al. 1999. Potentantitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and in vivo human cancer cell line panel. Cancer Res. 59:4042–4049.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Foster R, Sun X, Yin Q, Li Y, Hanley G, Stuart C, Gan Y, Li C, Zhang Z, Yin D. 2008. Restraint stress induces lymphocyte reduction through p53 and PI3K/NF-kappaB pathways. J Neuroimmunol. 200:71–76.
   PubMed Web of Science ®Google Scholar
• Zhao H, Yenari MA, Cheng D, Sapolsky RM, Steinberg GK. 2003. Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J Neurochem. 85:1026–1036.
   PubMed Web of Science ®Google Scholar