172
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Epidermal growth factor, basic fibroblast growth factor and platelet-derived growth factor-bb can substitute for fetal bovine serum and compete with human platelet-rich plasma in the ex vivo expansion of mesenchymal stromal cells derived from adipose tissue

, , , , &
Pages 933-943 | Received 18 Aug 2010, Accepted 13 Apr 2011, Published online: 30 May 2011

References

  • Kolf CM, Cho E, Tuan RS. Mesenchymal stromal cells. Biology of adult stem cells: regulation of niche, self-renewal and differentiation. Arthritis Res Ther. 2007;7:204–14.
  • Bruder SP, Kurth AA, Shea M, Hayes WC, Jaiswal N, Kadiyala S. Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells. J Orthop Res. 1998;16:155–62.
  • De Kok I, Peter SJ, Archambault M, van den Bos C, Kadiyala S, Aukhil I, . Investigation of allogeneic mesenchymal stem cell-based alveolar bone formation: preliminary findings. Clin Oral Implants Res. 2003;14:481–9.
  • Wakitani S, Goto T, Pineda SJ, Young RG, Mansour JM, Caplan AI, . Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage. J Bone Joint Surg Am. 1994;76:579–92.
  • Awad HA, Boivin GP, Dressler MR, Smith FN, Young RG, Butler DL. Repair of patellar tendon injuries using a cell-collagen composite. J Orthop Res. 2003;21:420–31.
  • Murphy JM, Fink DJ, Hunziker EB, Burry FP. Stem cell therapy in a caprine model of osteoarthritis. Arthritis Rheum. 2003;48:3464–74.
  • Wakitani S, Saito T, Caplan AI. Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve. 1995;18:1417–26.
  • Pittenger MF, Martin BJ. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res. 2004;95:9–20.
  • Kawada H, Fujita J, Kinjo K, Matsuzaki Y, Tsuma M, Miyatake H, . Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood. 2004;104:3581–7.
  • Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci USA. 1999;96:10711–6.
  • Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res. 2000;61:364–70.
  • Horwitz EM, Prockop DJ, Fitzpatrick LA, Koo WW, Gordon PL, Neel M, . Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med. 1999;5:309–13.
  • Horwitz EM, Gordon PL, Koo WK, Marx JC, Neel MD, McNall RY, . Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proc Natl Acad Sci USA. 2002;99:8932–7.
  • Le Blanc K, Rasmusson I, Sundberg B, Götherström C, Hassan M, Uzunel M, . Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet. 2004;363:1439–41.
  • Koc ON, Gerson SL, Cooper BW, Dyhouse SM, Haynesworth SE, Caplan AI, . Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol. 2000;18:307–16.
  • Multicenter Clinical Trial for the Evaluation on Mesenchymal Stem Cells from Adipose Tissue in Patient with Chronic Graft versus Host Disease (CMM/EICH/2008). Available at: http://clinicaltrials.gov
  • Treatment of refractory (acute or chronic) graft versus host disease by the infusion of expanded in vitro allogenic mesenchymal stem cell. Available at: http://clinicaltrials.gov
  • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 2005;105: 1815–22.
  • Di Nicola M, Carlo Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, . Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or non-specific mitogenic stimuli. Blood. 2002;99:3838–43.
  • Krampera M, Glennie S, Dyson J, Cott D, Laylor R, Simpson E, . Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood. 2003;101:3722–9.
  • Doerr HW, Cinatl J, Sturmer M, Rabenau HF. Prions and orthopedic surgery. Infection. 2003;31:163–71.
  • Spees JL, Gregory CA, Singh H, Tucker HA, Peister A, Lynch PJ, . Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy. Mol Ther. 2004;9:747–56.
  • Doucet C, Ernou I, Zhang Y, Llense JR, Begot L, Holy X, . Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy application. J Cell Physiol. 2005;205:228–36.
  • Kocaoemer A, Kern S, Uter H, Bieback K. Human AB serum and thrombin-activated platelet-rich plasma are suitable alternatives to fetal calf serum for the expansion of mesenchymal stem cells from adipose tissue. Stem Cells. 2007;25: 1270–8.
  • Battula VL, Bareiss PM, Treml S, Conrad S, Albert I, Hojak S, . Human placenta and bone marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation. Differentiation. 2007;75:279–91.
  • Krampera M, Pasini A, Rigo A, Scupoli MT, Tecchio C, Malpeli G, . HB-EGF/HER-1 signaling in bone marrow mesenchymal stem cells: induced cell expansion and reversibly preventing multilineage differentiation. Blood. 2005;106:59–66.
  • Longobardi L, O'Rear L, Aakula S, Johnstone B, Shimer K, Chytil A, . Effect of IGF-I in the condrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF signalling. J Bone Min Res. 2006;21:626–36.
  • Solchaga LA, Penick K, Porter JD, Goldberg VM, Caplan AI, Welter JF. FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. J Cell Physiol. 2005;203:398–409.
  • Tamana K, Fan VH, Griffith LG, Blair HC, Wells A. Epidermal growth factor as a candidate for ex vivo expansion of bone marrow-derived mesenchymal stem cells. Stem Cells. 2006; 24:686–95.
  • Thomas T, Gori F, Spelberg TC, Khosla S, Riggs B, Conover CA. Response of biopotential human marrow stromal cells to insulin-like growth factors: effect on binding protein production, proliferation, and commitment to osteoblasts and adipocytes. Endocrinology. 1999;140:5036–44.
  • Yangxin L, XiYong Y, ShuGuang L, XiaoHong L, Saidan Z, Yao-Hua S. Insulin-like growth factor 1 enhances the migratory capacity of mesenchymal stem cells. Biochem Biophys Res Comm. 2007;356:780–4.
  • Stenderup K, Justuesen J, Clausen C, Kassem M. Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone. 2003;3: 919–26.
  • McIntyre A, Bjornson BH. Human bone marrow stromal cell colonies: response to hydrocortisone and dependence on platelet-derived growth factor. Exp Hematol. 1986;14:833–9.
  • Keshavarz E, Hoare M, Dunnill P. Biochemical engineering aspects of cell disruption. Verrall MS, Hudson MJ. Separations for Biotechnology. Chichester: Ellis Horwood Series; 1987;34:62–79.
  • Freshney RI. Culture of Animal Cells. A Manual of Basic technique. 5th. Wiley-Liss Publication. New Jersey. 2005.
  • Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini FC, Krause DS, . Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315–7.
  • Storms RW, Trujillo AP, Springer JB, Shah L, Colvin OM, Ludeman SM, . Isolation of primitive human hematopoietic progenitors on the basis of aldehyde dehydrogenase activity. Proc Natl Acad Sci USA. 1999;96:9118–23.
  • Storms RW, Green PD, Safford KM, Niedzwiecki D, Cogle CR, Colvin OM, . Distinct hematopoietic progenitor compartments are delineated by the expression of aldehyde dehydrogenase and CD34. Blood. 2005;106:95–102.
  • Christ O, Lucke K, Leung K, Hamilton M, Eaves A, Smith C, . Improved purification of hematopoietic stem cells based on their elevated aldehyde dehydrogenase activity. Haematologica. 2007;92:1165–72.
  • Sahovic EA, Colvin M, Hilton J, Ogawa M. Role for aldehyde dehydrogenase in survival of progenitors for murine blast cell colonies after treatment with 4-hydroperoxycyclophosphamide in vitro. Cancer Res. 1998;48:1223–6.
  • Gruber R, Karreth F, Kandler B, Fuerst G, Rot A, Fisher MB, . Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow derived-mesenchymal progenitor cells under in vitro conditions. Platelets. 2004;15:29–35.
  • Mitchell JB, McIntosh K, Zvonic S, Garrett S, Floyd E, Kloster A, . Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers. Stem Cells. 2006;24:376–85.
  • Im GI, Shin YW, Lee KB. Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells. Osteoarth Cart. 2005;13:845–53.
  • Hui JH, Li L, Teo YH, Ouyang HW, Lee EH. Comparative study of the ability of mesenchymal stem cells derived from bone marrow, periosteum and adipose tissue in treatment of partial growth arrest in rabbit. Tissue Eng. 2005;11:904–12.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.