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Letter to the Editor

Is volume the only factor that impacts cord blood processing efficiency?

Pages 1022-1023 | Received 06 Mar 2012, Accepted 25 Apr 2012, Published online: 25 May 2012

References

  • Meyer-Monard S, Tichelli A, Troeger C, Arber C, de Faveri GN, Gratwohl A, et al.Initial cord blood unit volume affects mononuclear cell and CD34+ cell-processing efficiency in a non-linear fashion. Cytotherapy. 2012;14:215–22.
  • Harris DT, McGaffey AP, Brown HL.The effect of collection bag anticoagulant on umbilical cord blood stem cell yield. Transfusion. 2008;48(S2):206A.
  • Li J, Neugen M, Chapman J. Effect of anticoagulant to blood volume ratio on blood stratification and wbc recovery using centrifugation. Transfusion. 2009;49(S):SP335.
  • Pope B, Mitsakos K, Bilgin A, Hokin B, Grant R. Predicting overall viability of cord blood harvests. Transfusion. 2012;52:1079–1085.
  • Harris DT, Glasser L, Badowski MS, Brown H, Brown KS. The effects of anticoagulants on cord blood viability from collection to processing. Blood. 2011;118:Abstract 1923.
  • Papassavas AC, Gioka V, Chatzistamatiou T, Kokkinos T, Anagnostakis I, Gecka G, .A strategy of splitting individual high volume cord blood units into two half subunits prior to processing increases the recovery of cells and facilitates ex vivo expansion of the infused haematopoietic progenitor cells in adults. Int J Lab Hematol. 2008;30:124–32.

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