Synthesis, antiproliferative and antimicrobial activity of new Mannich bases bearing 1,2,4-triazole moiety

References

• Turan-Zitouni G, Kaplanciki ZA, Erol K, Kiliç FS. Synthesis and analgesic activity of some triazoles and triazolothiadiazines. Farmaco 1999;54:218–23
   PubMedGoogle Scholar
• Omar K, Geronikaki A, Zoumpoulakis P, et al. Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. Bioorg Med Chem 2012;18:426–32
   Web of Science ®Google Scholar
• Colin X, Sauleau A, Coulon J. 1,2,4-Triazolo mercapto and aminonitriles as potent antifungal agents. Bioorg Med Chem Lett 2003;13:2601–5
   PubMed Web of Science ®Google Scholar
• Byrak H, Demirbas A, Demirbas N, Karaoglu SA. Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. Eur J Med Chem 2009;44:4362–6
   PubMed Web of Science ®Google Scholar
• Padmavathi V, Sudhakar GR, Padmaja A, et al. Synthesis, antimicrobial and cytotoxic activities of 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles. Eur J Med Chem 2009;44:2106–12
   PubMed Web of Science ®Google Scholar
• Al-Soud YA, Al-Dweri MN, Al-Masoudi NA. Synthesis, antitumor and antiviral properties of some 1,2,4-triazole derivatives. Farmaco 2004;59:775–83
   PubMedGoogle Scholar
• Salgm-Cökşen U, Gökhan-Kelekçi N, Göktaş Ö, et al. 1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities. Bioorg Med Chem 2007;15:5738–51
   PubMed Web of Science ®Google Scholar
• Palaska E, Şahin G, Kelicen P, et al. Synthesis and anti-inflammatory activity of 1-acylthiosemicarbazides, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazole-3-thiones. Farmaco 2002;57:101–7
   PubMedGoogle Scholar
• Shiradkar MR, Murahari KK, Gangadasu HR, et al. Synthesis of new S-derivatives of clubbed triazolyl thiazole as anti-Mycobacterium tuberculosis agents. Bioorg Med Chem 2007;15:3997–4008
   PubMed Web of Science ®Google Scholar
• Pandeya SN, Sriram D, Nath G, DeClercq E. Synthesis, antibaceterial and anti-HIV activities of Schiff and Mannich bases derived from isation derivatives and N-[4-(4′-chlorophenyl)thiazol-2-yl] thiosemicarbazide. Eur J Pharm Sci 1999;9:25–31
   PubMed Web of Science ®Google Scholar
• Almajan GL, Barbuceanu S-F, Almajan E-R, et al. Synthesis, characeteriaztion and antibaceterial acitivity of some triazole Mannich bases carrying diphenylsulfone moieties. Eur J Med Chem 2009;44:3083–9
   PubMed Web of Science ®Google Scholar
• Idhayadhulla A, Kumar RS, Nasser AJA, et al. Synthesis of some Mannich base derivatives and their antimicrobial activity study. Arab J Chem 2011. doi: 10.1016/j.arabjc.2010.12.025
   Google Scholar
• Koparir M, Orek C, Parlak AE, et al. Synthesi and biological activities of some novel aminomethyl derivatives of 4-substituted-5-(2-thienyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones. Eur J Med Chem 2013;63:340–6
   PubMed Web of Science ®Google Scholar
• Shivarama H, Sooryanarayana R, Shirdhara K, Akberali PM. Studies on arylfuran derivatives Part XI. Synthesis, characterization and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety. Farmaco 2000;55:338–44
   PubMedGoogle Scholar
• Karthikeyan MS, Prasad DJ, Poojary B, et al. Synthesis and biological activity of Schiff and Mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety. Bioorg Med Chem 2006;14:7482–9
   PubMed Web of Science ®Google Scholar
• Shivarama H, Veerendra B, Shivananda MK, Poojary B. Synthesis characterization and anticancer activity studies on some Mannich base derived form 1,2,4-triazoles. Eur J Med Chem 2003;38:759–67
   PubMed Web of Science ®Google Scholar
• Sujith KV, Rao JN, Shetty P, Kalluraya B. Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety. Eur J Med Chem 2009;44:3697–702
   PubMed Web of Science ®Google Scholar
• Obniska J, Rzepka S, Kamiński K. Synthesis and anticonvulsant activity of new N-Mannich bases derived form 3-(2-fluorophenyl)- and 3-(2-bromophenyl)-pyrrolidine-2,5-diones. Part II. Bioorg Med Chem 2012;20:4872–80
   PubMed Web of Science ®Google Scholar
• Tramontini M, Agioline L, Ghedeni N. Mannich bases in polymer chemistry. Polymer 1988;29:771–88
   Web of Science ®Google Scholar
• Jia XD, Chen XN, De Huo C, et al. Cross double Mannich reaction catalyzed by I2: synthesis of highly substituted 4-piperidones. Chin Chem Lett 2012;23:309–12
   Web of Science ®Google Scholar
• Tramontini M, Angiolini L. Further advances in the chemistry of Mannich bases. Tetrahedron 1990;46:1791–837
   Web of Science ®Google Scholar
• Wyrzykiewicz E, Wendzonka M, Kedzia B. Synthesis and antimicrobial activity of new (E)-4-[piperidino (4′-methylpiperidino-, morpholino-)N-alkoxy]stilbenes. Eur J Med Chem 2006;41:519–25
   PubMed Web of Science ®Google Scholar
• Foroumadi AR, Ghodsi S, Emami S, et al. Synthesis and antibacterial activity of new fluoroquinolones containing a substituted N-(phenethyl) piperazine moiety. Bioorg Med Chem Lett 2006;16:3499–503
   PubMed Web of Science ®Google Scholar
• Holla BS, Veerendra B, Shivananda MK, Poojary B. Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles. Eur J Med Chem 2003;38:759–67
   PubMed Web of Science ®Google Scholar
• Dimmock JR, Chamankkah M, Allen TM, Halleran S. Mannich bases of 2-arylmethylenecyclohexanone with cytotoxic activity. Pharmazie 1995;50:221–2
   PubMed Web of Science ®Google Scholar
• Dimmock JR, Kumar P. Anticancer and cytotoxic properties of Mannich bases. Curr Med Chem 1997;4:1–22
   Web of Science ®Google Scholar
• Popiołek Ł, Kosikowska U, Dobosz M, Malm A. Synthesis and in vitro antimicrobial activity of new 4-phenyl-5-methyl-4H-1,2,4-triazole-3-thione derivatives. J Enzym Inhib Med Chem 2013;28:479–88
   PubMed Web of Science ®Google Scholar
• CLSI. Performance standards for antimicrobial susceptibility testing; Eighteenth International Supplement. CLSI document M7-MIC. Wayne, PA: Clinical Laboratory Standards Institute; 2008
   Google Scholar
• O’Donnell F, Smyth TJP, Ramachandran VN, Smyth WF. A study of the antimicrobial activity of selected synthetic and naturally occurring quinolines. Int J Antimicrob Agents 2010;35:30–8
   PubMed Web of Science ®Google Scholar
• Makovik Yu V, Knish EG, Panasenko OI. Synthesis, transformations, antimicrobial and antifungal activities of 5-(pyridin-3-yl)-4-R-1,2,4-triazole-3-thiones. Medichna Khimiya 2007;9:95–8
   Google Scholar
• Popiołek Ł, Kosikowska U, Dobosz M, Malm A. Synthesis and antimicrobial properties of new thiosemicarbazide, 1,2,4-triazole, and 1,3,4-thiadiazole derivatives of sulfanylacetic acid. Phosphorus Sulfur 2012;187:468–81
   Web of Science ®Google Scholar
• Pitucha M, Wujec M, Dobosz M, et al. Synthesis and biological action of 1-aminomethyl derivatives of 3-R-4-phenyl-Δ2-1,2,4-triazoline-5-thione. Acta Pol Pharm 2005;62:443–9
   PubMedGoogle Scholar
• Siwek A, Paneth P. Computational studies of the cyclization of thiosemicarbazides. J Phys Org Chem 2007;20:463–8
   Web of Science ®Google Scholar
• Siwek A, Wujec M, Wawrzycka-Gorczyca I, et al. Thiol-thione tautomeric forms recognition on the example of 4-[3-(2-Methyl-furan-3-yl)-5-thioxo-1,2,4-triazolin-4-yl]acetic acid. Heteroatom Chem 2008;19:337–44
   Web of Science ®Google Scholar
• Plech T, Wujec M, Siwek A, et al. Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. Eur J Med Chem 2011;46:241–8
   PubMed Web of Science ®Google Scholar
• Plech T, Wujec M, Majewska M, et al. Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity. Med Chem Res 2013;22:2531–7
   PubMed Web of Science ®Google Scholar