915
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Retinol oxidation to retinoic acid in human thyroid glandular cells

, , , &
Pages 796-803 | Received 17 Jul 2013, Accepted 27 Sep 2013, Published online: 10 Feb 2014

References

  • Gudas LJ. Retinoids and vertebrate development. J Biol Chem 1994;269:15399–402
  • Dolle P. Developmental expression of retinoic acid receptors (RARs). Nucl Recept Signal 2009;7:e006
  • Mark M, Ghyselinck NB, Chambon P. Function of retinoic acid receptors during embryonic development. Nucl Recept Signal 2009;7:e002
  • Gudas LJ, Sporn MB, Roberts AB. Cellular biology and biochemistry of the retinoids. In: Sporn MB, Roberts AB, Goodman DS, eds. The retinoids: biology, chemistry, and medicine. New York (NY): Raven Press, Ltd; 1994:443–520
  • Lotan R. Effect of vitamin A and its analogues (retinoids) on normal and neoplastic cells. Biochim Biophys Acta 1980;605:33–91
  • Orphanos CE. Oral retinoids-present status. Br J Dermatol 1980;103:473–81
  • Chytil F. Retinoic acid, biochemistry, pharmacology, toxicology and therapeutic use. Pharmacol Rev 1984;36:93S–100S
  • Kraemer KH, Di Giovanna JJ, Moshell AN, et al. Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin. N Engl J Med 1988;318:1633–7
  • Napoli JL. Retinoic acid biosynthesis and metabolism. FASEB J 1996;10:993–1001
  • Napoli JL. Physiological insights into all-trans-retinoic acid biosynthesis. Biochim Biophys Acta 2012;1821:152–67
  • Jette C, Peterson PW, Sandoval IT, et al. The tumor suppressor adenomatous polyposis coli and caudal related homeodomain protein regulate expression of retinol dehydrogenase L. J Biol Chem 2004;279:34397–405
  • Zhang M, Hu P, Krois CR, et al. Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse. FASEB J 2007;21:2886–96
  • Siegenthaler JA, Ashique AM, Zarbalis K, et al. Retinoic acid from the meninges regulates cortical neuron generation. Cell 2009;139:597–609
  • Ziouzenkova O, Orasanu G, Sharlach M, et al. Retinaldehyde represses adipogenesis and diet-induced obesity. Nat Med 2007;13:695–702
  • Dupé V, Matt N, Garnier JM, et al. A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment. Proc Natl Acad Sci USA 2003;100:14036–41
  • Halilagic A, Ribes V, Ghyselinck NB, et al. Retinoids control anterior and dorsal properties in the developing forebrain. Dev Biol 2007;303:362–75
  • Taibi G, Nicotra CMA. Xanthine oxidase catalyzes the oxidation of retinol. J Enzyme Inhib Med Chem 2007;22:471–6
  • Taibi G, Paganini A, Gueli MC, et al. Xanthine oxidase catalyzes the synthesis of retinoic acid. J Enzyme Inhib 2001;16:275–85
  • Taibi G, Di Gaudio F, Nicotra CMA. Xanthine dehydrogenase processes retinol to retinoic acid in human mammary epithelial cells. J Enzyme Inhib Med Chem 2008;23:317–27
  • Ottonello S, Scita G, Mantovani G, et al. Retinol bound to cellular retinol-binding protein is a substrate for cytosplasmic retinoic acid synthesis. J Biol Chem 1993;268:27133–42
  • Kuppumbatti YS, Bleiweiss IJ, Mandeli JP, et al. Cellular retinol-binding protein expression and breast cancer. J Natl Cancer Inst 2000;92:475–80
  • Hayden LJ, Satre MA. Alterations in cellular retinol metabolism contribute to differential retinoid responsiveness in normal human mammary epithelial cells versus breast cancer cells. Breast Cancer Res Treat 2002;72:95–105
  • Taibi G, Carruba G, Cocciadiferro L, et al. Low Levels of both xanthine dehydrogenase and cellular retinol binding protein are responsible for retinoic acid deficiency in malignant human mammary epithelial cells. Steroid Enzym Cancer: Ann NY Acad Sci 2009;1155:268–72
  • Human Protein Atlas, by the Knut & Alice Wallenberg foundation, Uppsala University. Version: 10.0. Available from: http://www.proteinatlas.org/ [last accessed 12 Sept 2012]
  • Todaro M, Iovino F, Eterno V, et al. Tumorigenic and metastatic activity of human thyroid cancer stem cells. Cancer Res 2010;70:8874–85
  • Frolik CA, Tavela TE, Peck GL, Sporn MB. High-pressure liquid chromatographic determination of 13-cis-retinoic acid and all-trans-retinoic acid in human plasma. Anal Biochem 1978;86:743–50
  • Kock R, Delvoux B, Greiting H. A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases. Eur J Clin Chem Clin Biochem 1993;31:303–10
  • Groenendijk GWT, Jensen PAA, Bonting SL, Daemen FJM. Analysis of geometrically isomeric vitamin A compounds. Methods Enzymol 1980;67:203–20
  • Snedecor G, Cochran W. Statistical methods. Ames (IA): Iowa State University Press; 1967:120–34
  • Nishino T, Okamoto K, Egere BT, et al. Mammalian xanthine oxidoreductase – mechanism of transition from xanthine dehydrogenase to xanthine oxidase. FEBS J 2008;275:3278–89
  • Chen Q, Park HC, Goligorsky MS, et al. Untargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in mice. PLoS One 2012;7:e37149,1–14
  • Cheung KJ, Tzameli I, Pissios P, et al. Xanthine oxidoreductase is a regulator of adipogenesis and PPAR-γ activity. Cell Metab 2007;5:115–28
  • Ohtsubo T, Rovira, II, Starost MF, et al. Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2. Circ Res 2004;95:1118–24
  • Webb AJ, Milsom AB, Rathod KS, et al. Mechanisms underlying erythrocyte and endothelial nitrite reduction to NO in hypoxia: role for xanthine oxidoreductase and eNOS. Circ Res 2008;103:957–64
  • Zhang Z, Blake DR, Stevens CR, et al. A reappraisal of xanthine dehydrogenase and oxidase in hypoxic reperfusion injury: the role of NADH as an electron donor. Free Radic Res 1998;28:151–64
  • Zhang R, Pinson A, Samuni A. Both hydroxylamine and nitroxide protect cardiomyocytes from oxidative stress. Free Radic Biol Med 1998;24:66–75
  • Taibi G, Carruba G, Miceli V, et al. Estradiol decreases xanthine dehydrogenase enzyme activity and protein expression in non-tumorigenic and malignant human mammary epithelial cells. J Cell Biochem 2009;108:688–92
  • Landmesser U, Spiekermann S, Preuss C, et al. Angiotensin II induces endothelial xanthine oxidase activation-role for endothelial dysfunction in patients with coronary disease. Artherioscler Thromb Vasc Biol 2007;27:943–8
  • Yasmeen R, Jeyakumar SM, Reichert B, et al. The contribution of vitamin A to autocrine regulation of fat depots. Biochim Biophys Acta 2012;1821:190–7
  • Bonet ML, Ribot J, Palou A. Lipid metabolism in mammalian tissues and its control by retinoic acid. Biochim Biophys Acta 2012;1821:177–89
  • Xue JC, Schwarz EJ, Chawla A, Lazar MA. Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARγ. Mol Cell Biol 1996;16:1567–75
  • Safonova I, Darimont C, Amri EZ, et al. Retinoids are positive effectors of adipose cell differentiation. Mol Cell Endocrinol 1994;104:201–11
  • Szanto A, Nagy L. Retinoids potentiate peroxisome proliferator-activated receptor γ action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells. Mol Pharmacol 2005;67:1935–43
  • Zizola CF, Frey SK, Jitngarmkusol S, et al. Cellular retinol-binding protein type I (CRBP-I) regulates adipogenesis. Mol Cell Biol 2010;30:3412–20
  • del Rincòn SV, Rousseau C, Samanta R, Miller WH Jr. Retinoic acid-induced growth arrest of MCF-7 cells involves the selective regulation of the IRS-1/PI 3-kinase/AKT pathway. Oncogene 2003;22:3353–60
  • Drill VA. Interrelations between thyroid function and vitamin metabolism. Physiol Rev 1943;23:355–79
  • Morley JE, Melmed S, Reed A, et al. Effect of vitamin A on the hypothalamo-pituitary-thyroid axis. Am J Physiol-Cell Ph 1980;238:E174–9
  • Xu P, Huecksteadt TP, Hoidal JR. Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH). Genomics 1996;34:173–80
  • McPherson LA, Woodfield GW, Weigel RJ. AP2 Transcription factors regulate expression of CRABPII in hormone hesponsive breast carcinoma. J Surgical Res 2007;138:71–8
  • Kawaguchi R, Zhong M, Kassai M, et al. STRA6-catalyzed vitamin A influx, efflux and, exchange. J Memb Biol 2012;245:731–45

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.