First trimester contingent test as a screening method for Down’s syndrome. A prospective study in the general population

References

• Malone FD, Canick JA, Ball RH, Nyberg DA, Comstock CH, Bukowski R, Berkowitz RL, et al.; First- and Second-Trimester Evaluation of Risk (FASTER) Research Consortium. First-trimester or second-trimester screening, or both, for Down’s syndrome. N Engl J Med 2005;353:2001–2011.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Wright D, Baker A, Sahota D, Nicolaides KH. Screening for trisomy 21 by maternal age fetal nuchal translucency thickness, free beta human chorionic gonadotropin and pregnancy-associated plasma protein-A. Ultrasound Obsted Gynecol 2008;31:618–624.
   PubMed Web of Science ®Google Scholar
• Wright D, Spencer K, Kagan KK, Tørring N, Petersen OB, Christou A, Kallikas J, Nicolaides KH. First-trimester combined screening for trisomy 21 at 7-14 weeks’ gestation. Ultrasound Obstet Gynecol 2010;36:404–411.
   PubMed Web of Science ®Google Scholar
• Wald NJ, Watt HC, Hackshaw AK. Integrated screening for Down’s syndrome on the basis of tests performed during the first and second trimesters. N Engl J Med 1999;341:461–467.
   PubMed Web of Science ®Google Scholar
• Wright D, Bradbury I, Benn P, Cuckle H, Ritchie K. Contingent screening for Down syndrome is an efficient alternative to non-disclosure sequential screening. Prenat Diagn 2004;24:762–766.
   PubMed Web of Science ®Google Scholar
• Wright D, Bradbury I, Cuckle H, Gardosi J, Tonks A, Standing S, Benn P. Three-stage contingent screening for Down syndrome. Prenat Diagn 2006;26:528–534.
   PubMedGoogle Scholar
• Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O. Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. Ultrasound Obstet Gynecol 2005;25:221–226.
   PubMed Web of Science ®Google Scholar
• Programa andaluz de cribado de anomalías congénitas (PACAC). Available at: www.juntadeandalucia.es/servicioandaluzdesalud/publicaciones.
   Google Scholar
• Kagan KO, Cicero S, Staboulidou I, Wright D, Nicolaides KH. Fetal nasal bone in screening for trisomies 21, 18 and 13 and Turner syndrome at 11–13 weeks of gestation. Ultrasound Obsted Gynecol 2009;33:259–264.
   PubMed Web of Science ®Google Scholar
• Maiz N, Valencia C, Kagan KO, Wright D, Nicolaides KH. Ductus venosus Doppler in screening for trisomies 21, 18 and 13 and Turner syndrome at 11–13 weeks of gestation. Ultrasound Obsted Gynecol 2009;33:512–517.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Valencia C, Livanos P, Wright D, Nicolaides KH. Tricuspid regurgitation in screening for trisomies 21, 18 and 13 and Turner syndrome at 11 + 0 to 13 + 6 weeks of gestation. Ultrasound Obsted Gynecol 2009;33:18–22.
   PubMed Web of Science ®Google Scholar
• Sahota DS, Leung TY, Chan LW, Law LW, Fung TY, Chen M, Lau TK. Comparison of first-trimester contingent screening strategies for Down syndrome. Ultrasound Obstet Gynecol 2010;35:286–291.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Staboulidou I, Cruz J, Wright D, Nicolaides KH. Two-stage first-trimester screening for trisomy 21 by ultrasound assessment and biochemical testing. Ultrasound Obstet Gynecol 2010;36:542–547.
   PubMed Web of Science ®Google Scholar
• Muñoz-Cortes M, Arigita M, Falguera G, Seres A, Guix D, Baldrich E, Acera A, et al. Contingent screening for Down síndrome completed in the first trimester. Multicenter study. Ultrasound Obsted Gynecol, in press.
   Google Scholar
• Cicero S, Avgidou K, Rembouskos G, Kagan KO, Nicolaides KH. Nasal bone in first-trimester screening for trisomy 21. Am J Obstet Gynecol 2006;195:109–114.
   PubMed Web of Science ®Google Scholar
• Borrell A, Gonce A, Martinez JM, Borobio V, Fortuny A, Coll O, Cuckle H. First-trimester screening for Down syndrome with ductus venosus Doppler studies in addition to nuchal translucency and serum markers. Prenat Diagn 2005;25:901–905.
   PubMed Web of Science ®Google Scholar
• Bermejo E, Cuevas L, Mendioroz J, Martinez-Frías ML. Vigilancia epidemiológica de anomalías congénitas en España: Análisis de los datos del registro del ECEMC en el período 1980–2008. Boletín del ECEMC. Revista de Dismorfología y Epidemiología. 2009;8:64–91.
   Google Scholar
• Direcció General de Salut Pública. Departament de Salut Pública. Generalitat de Catalunya. Indicadors de Salut Maternoinfantil a Catalunya 2003–2005. Available at:http://www.gencat.cat/salut/depsalut/html/ca/dir2057/indica2003.pdf
   Google Scholar
• Christiansen M, Olesen Larsen S. An increase in cost-effectiveness of first trimester maternal screening programmes for fetal chromosome anomalies is obtained by contingent testing. Prenat Diagn 2002;22:482–486.
   PubMedGoogle Scholar
• Vadiveloo T, Crossley JA, Aitken DA. First-trimester contingent screening for Down syndrome can reduce the number of nuchal translucency measurements required. Prenat Diagn 2009;29:79–82.
   PubMedGoogle Scholar
• Sahota DS, Leung TY, Chan LW, Law LW, Fung TY, Chen M, Lau TK. Comparison of first-trimester contingent screening strategies for Down syndrome. Ultrasound Obsted Gynecol 2010;35:286–291.
   PubMed Web of Science ®Google Scholar
• Malone FD, Canick JA, Ball RH, Nyberg DA, Comstock CH, Bukowski R, Berkowitz RL, et al. First and Second-Trimester Evaluation of Risk (FASTER) Research Consortium. First trimester or second-trimester screening, or both, for Down’s syndrome. N Engl J Med. 2005;353:2001–2011.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Wright D, Baker A, Sahota D, Nicolaides KH. Screening for trisomy 21 by maternal age, fetal nuchal translucency thickness, free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A. Ultrasound Obstet Gynecol 2008;31:618–624.
   PubMed Web of Science ®Google Scholar
• Wright D, Spencer K, Kagan KK, Torring N, Petersen OB, Christou A, Kallikas J, et al. First-trimester combined screening for trisomy 21 at 7-14 weeks’ gestation. Ultrasound Obsted Gynecol 2010;36:404–411.
   PubMed Web of Science ®Google Scholar
• Wald NJ, Watt HC, Hackshaw AK. Integrated screening for Down’s syndrome on the basis of tests performed during the first and second trimesters. N Engl J Med 1999;341:461–467.
   PubMed Web of Science ®Google Scholar
• Wright D, Bradbury I, Benn P, Cuckle H, Ritchie K. Contingent screening for Down syndrome is an efficient alternative to non-disclosure sequential screening. Prenat Diagn. 2004;24:762–766.
   PubMed Web of Science ®Google Scholar
• Wright D, Bradbury I, Cuckle H, Gardosi J, Tonks A, Standing S, Benn P. Three-stage contingent screening for Down syndrome. Prenat Diagn 2006;26:528–534.
   PubMedGoogle Scholar
• Nicolaides KH, Spencer K, Avgidou K, Faiola S, Falcon O. Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening. Ultrasound Obsted Gynecol 2005;25:221–226.
   PubMed Web of Science ®Google Scholar
• Programa andaluz de cribado de anomalías congénitas (PACAC). Available at: www.juntadeandalucia.es/servicioandaluzdesalud/publicaciones.
   Google Scholar
• Kagan KO, Cicero S, Staboulidou I, Wright D, Nicolaides KH. Fetal nasal bone in screening for trisomies 21, 18 and 13 and Turner syndrome at 11-13 weeks of gestation. Ultrasound Obstet Gynecol 2009;33:259–264.
   PubMed Web of Science ®Google Scholar
• Maiz N, Valencia C, Kagan KO, Wright D, Nicolaides KH. Ductus venosus Doppler in screening for trisomies 21, 18 and 13 and Turner syndrome at 11-13 weeks of gestation. Ultrasound Obstet Gynecol 2009;33:512–517.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Valencia C, Livanos P, Wright D, Nicolaides KH. Tricuspid regurgitation in screening for trisomies 21, 18 and 13 and Turner syndrome at 11+0 to 13+6 weeks of gestation. Ultrasound Obstet Gynecol 2009;33:18–22.
   PubMed Web of Science ®Google Scholar
• Sahota DS, Leung TY, Chan LW, Law LW, Fung TY, Chen M, Lau TK. Comparison of first-trimester contingent screening strategies for Down syndrome. Ultrasound Obsted Gynecol 2010;35:286–291.
   PubMed Web of Science ®Google Scholar
• Kagan KO, Staboulidou I, Cruz J, Wright D, Nicolaides KH. Two-stage first-trimester screening for trisomy 21 by ultrasound assessment and biochemical testing.Ultrasound Obsted Gynecol. 2010;36:542–547.
   PubMed Web of Science ®Google Scholar
• Muñoz-Cortes M, Arigita M, Falguera G, Seres A, Guix D, Baldrich E, Acera A, et al. Contingent screening for Down syndrome completed in the first trimester: a multicenter study. Ultrasound Obstet Gynecol 2012;39:396–400.
   PubMed Web of Science ®Google Scholar
• Cicero S, Avgidou K, Rembouskos G, Kagan KO, Nicolaides KH. Nasal bone in first-trimester screening for trisomy 21. Am J Obstet Gynecol. 2006;195:109–114.
   PubMed Web of Science ®Google Scholar
• Borrell A, Gonce A, Martinez JM, Borobio V, Fortuny A, Coll OCuckle H. First-trimester screening for Down syndrome with ductus venosus Doppler studies in addition to nuchal translucency and serum markers. Prenat Diagn 2005;25:901–905.
   PubMed Web of Science ®Google Scholar
• Bermejo E, Cuevas L, Mendioroz J, Martinez-Frías ML. Vigilancia epidemiológica de anomalías congénitas en España: Análisis de los datos del registro del ECEMC en el período 1980–2008. Boletín del ECEMC. Revista de Dismorfología y Epidemiología. 2009;8:64–91.
   Google Scholar
• Direcció General de Salut Pública. Departament de Salut Pública. Generalitat de Catalunya. Indicadors de Salut Maternoinfantil a Catalunya 2003–2005. Available at: http://www.gencat.cat/salut/depsalut/html/ca/dir2057/indica2003.pdf
   Google Scholar
• Christiansen M, Olesen Larsen S. An increase in cost- effectiveness of first trimester maternal screening programmes for fetal chromosome anomalies is obtained by contingent testing. Prenat Diagn 2002;22:482–486.
   PubMedGoogle Scholar
• Vadiveloo T, Crossley JA, Aitken DA. First-trimester contingent screening for Down syndrome can reduce the number of nuchal translucency measurements required. Prenat Diagn 2009;29:79–82.
   PubMedGoogle Scholar
• Sahota DS, Leung TY, Chan LW, Law LW, Fung TY, Chen M, Lau TK. Comparison of first-trimester contingent screening strategies for Down syndrome. Ultrasound Obsted Gynecol 2010;35:286–291.
   PubMed Web of Science ®Google Scholar