Increased oxidant generation in the metabolism of hypoxanthine to uric acid and endothelial dysfunction in early-onset and late-onset preeclamptic women

References

• MacKay AP, Berg CJ, Atrash HK. Pregnancy-related mortality from preeclampsia and eclampsia. Obstet Gynecol 2001;97:533–538.
   PubMed Web of Science ®Google Scholar
• Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 1989;161:1200–1204.
   PubMed Web of Science ®Google Scholar
• Hubel CA, Roberts JM, Taylor RN, Musci TJ, Rogers GM, McLaughlin MK. Lipid peroxidation in pregnancy: new perspectives on preeclampsia. Am J Obstet Gynecol 1989;161:1025–1034.
   PubMed Web of Science ®Google Scholar
• Wisdom SJ, Wilson R, McKillop JH, Walker JJ. Antioxidant systems in normal pregnancy and in pregnancy-induced hypertension. Am J Obstet Gynecol 1991;165:1701–1704.
   PubMed Web of Science ®Google Scholar
• Wang Y, Walsh SW, Kay HH. Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia. Am J Obstet Gynecol 1992;167:946–949.
   PubMed Web of Science ®Google Scholar
• Poranen AK, Ekblad U, Uotila P, Ahotupa M. Lipid peroxidation and antioxidants in normal and pre-eclamptic pregnancies. Placenta 1996;17:401–405.
   PubMed Web of Science ®Google Scholar
• Wang Y, Walsh SW. Placental mitochondria as a source of oxidative stress in pre-eclampsia. Placenta 1998;19:581–586.
   PubMed Web of Science ®Google Scholar
• Gurjit K, Soumya M, Alka S, Rajendra P. Alterations in lipid peroxidation and antioxidant status in pregnancy with preeclampsia. Mol Cell Biochem 2008;313: 37–44.
   PubMed Web of Science ®Google Scholar
• Fujimaki A, Watanabe K, Mori T, Kimura C, Shinohara K, Wakatsuki A. Placental oxidative DNA damage and its repair in preeclamptic women with fetal growth restriction. Placenta 2011;32:367–372.
   PubMed Web of Science ®Google Scholar
• Wang YP, Walsh SW, Guo JD, Zhang JY. The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood. Am J Obstet Gynecol 1991;165:1695–1700.
   PubMed Web of Science ®Google Scholar
• Chesley LC, Williams LO. Renal glomerular and tubular function in relation to the hyperuricemia of pre-eclampsia and eclampsia. Am J Obstet Gynecol 1945;50:367–375.
   Web of Science ®Google Scholar
• Hayashi T. Uric acid and endogenous creatinine clearance studies in normal pregnancy and toxemias of pregnancy. Am J Obstet Gynecol 1956;71:859–870.
   PubMed Web of Science ®Google Scholar
• Handler JS. The role of lactic acid in the reduced excretion of uric acid in toxemia of pregnancy. J Clin Invest 1960;39:1526–1532.
   PubMed Web of Science ®Google Scholar
• Many A, Hubel CA, Roberts JM. Hyperuricemia and xanthine oxidase in preeclampsia, revisited. Am J Obstet Gynecol 1996;174:288–291.
   PubMed Web of Science ®Google Scholar
• Suzuki S, Yoneyama Y, Sawa R, Otsubo Y, Takeuchi T, Araki T. Relation between serum uric acid and plasma adenosine levels in women with preeclampsia. Gynecol Obstet Invest 2001;51:169–172.
   PubMed Web of Science ®Google Scholar
• Many A, Hubel CA, Fisher SJ, Roberts JM, Zhou Y. Invasive cytotrophoblasts manifest evidence of oxidative stress in preeclampsia. Am J Pathol 2000;156:321–331.
   PubMed Web of Science ®Google Scholar
• Slemons J, Bogert L. The uric acid content of maternal and fetal blood. J Biol Chem 1917;32:63–69.
   Google Scholar
• Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID, Lloyd JK, Deanfield JE. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992;340:1111–1115.
   PubMed Web of Science ®Google Scholar
• Takase B, Uehata A, Akima T, Nagai T, Nishioka T, Hamabe A, Satomura K, et al. Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease. Am J Cardiol 1998;82:1535–9, A7.
   PubMed Web of Science ®Google Scholar
• Vogel RA. Measurement of endothelial function by brachial artery flow-mediated vasodilation. Am J Cardiol 2001;88:31E–34E.
   PubMed Web of Science ®Google Scholar
• Doshi SN, Naka KK, Payne N, Jones CJ, Ashton M, Lewis MJ, Goodfellow J. Flow-mediated dilatation following wrist and upper arm occlusion in humans: the contribution of nitric oxide. Clin Sci 2001;101:629–635.
   PubMed Web of Science ®Google Scholar
• Joannides R, Haefeli WE, Linder L, Richard V, Bakkali EH, Thuillez C, Lüscher TF. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 1995;91:1314–1319.
   PubMed Web of Science ®Google Scholar
• Sibai BM. Preeclampsia as a cause of preterm and late preterm (near-term) births. Semin Perinatol 2006;30:16–19.
   PubMed Web of Science ®Google Scholar
• Murphy DJ, Stirrat GM. Mortality and morbidity associated with early-onset preeclampsia. Hypertens Pregnancy 2000;19:221–231.
   PubMed Web of Science ®Google Scholar
• Ness RB, Sibai BM. Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia. Am J Obstet Gynecol 2006;195:40–49.
   PubMed Web of Science ®Google Scholar
• Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet 2005;365:785–799.
   PubMed Web of Science ®Google Scholar
• von Dadelszen P, Magee LA, Roberts JM. Subclassification of preeclampsia. Hypertens Pregnancy 2003;22:143–148.
   PubMed Web of Science ®Google Scholar
• Huppertz B. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 2008;51:970–975.
   PubMed Web of Science ®Google Scholar
• Trotti R, Carratelli M, Barbieri M. Performance and clinical application of a new, fast method for the detection of hydroperoxides in serum. Panminerva Med 2002;44:37–40.
   PubMed Web of Science ®Google Scholar
• Parmigiani S, Payer C, Massari A, Bussolati G, Bevilacqua G. Normal values of reactive oxygen metabolites on the cord-blood of full-term infants with a colorimetric method. Acta Biomed Ateneo Parmense 2000;71:59–64.
   PubMedGoogle Scholar
• Cesarone MR, Belcaro G, Carratelli M, Cornelli U, De Sanctis MT, Incandela I, Barsotti A, Terranova R, Nicolaides A. A simple test to monitor oxidative stress. International Angiology 1998;18:127–130.
   Web of Science ®Google Scholar
• Vallance P, Leone A, Calver A, Collier J, Moncada S. Accumulation of an endogenous inhibitor of NO synthesis in chronic renal failure. Lancet 1992;339:572–575.
   PubMed Web of Science ®Google Scholar
• Rubanyi GM, Romero JC, Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 1986;250:H1145–H1149.
   PubMed Web of Science ®Google Scholar
• Stein JH, Keevil JG, Wiebe DA, Aeschlimann S, Folts JD. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease. Circulation 1999;100:1050–1055.
   PubMed Web of Science ®Google Scholar
• Mori T, Shinohara K, Wakatsuki A, Watanabe K, Fujimaki A. Adipocytokines and endothelial function in preeclamptic women. Hypertens Res 2010;33:250–254.
   PubMed Web of Science ®Google Scholar
• Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular risk. N Engl J Med 2008;359:1811–1821.
   PubMed Web of Science ®Google Scholar
• Sibai BM, Gordon T, Thom E, Caritis SN, Klebanoff M, McNellis D, Paul RH. Risk factors for preeclampsia in healthy nulliparous women: a prospective multicenter study. The National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. Am J Obstet Gynecol 1995;172:642–648.
   PubMed Web of Science ®Google Scholar
• Powers RW, Bodnar LM, Ness RB, Cooper KM, Gallaher MJ, Frank MP, Daftary AR, Roberts JM. Uric acid concentrations in early pregnancy among preeclamptic women with gestational hyperuricemia at delivery. Am J Obstet Gynecol 2006;194:160.
   PubMed Web of Science ®Google Scholar
• Bainbridge SA, Roberts JM. Uric acid as a pathogenic factor in preeclampsia. Placenta 2008;29 Suppl A:S67–S72.
   PubMed Web of Science ®Google Scholar
• Chappell LC, Seed PT, Briley AL, Kelly FJ, Lee R, Hunt BJ, Parmar K, et al. Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial. Lancet 1999;354:810–816.
   PubMed Web of Science ®Google Scholar
• Poston L, Briley AL, Seed PT, Kelly FJ, Shennan AH; Vitamins in Pre-eclampsia (VIP) Trial Consortium. Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial. Lancet 2006;367:1145–1154.
   PubMed Web of Science ®Google Scholar
• Rumbold AR, Crowther CA, Haslam RR, Dekker GA, Robinson JS; ACTS Study Group. Vitamins C and E and the risks of preeclampsia and perinatal complications. N Engl J Med 2006;354:1796–1806.
   PubMed Web of Science ®Google Scholar
• Nagai R, Watanabe K, Wakatsuki A, Hamada F, Shinohara K, Hayashi Y, Imamura R, Fukaya T. Melatonin preserves fetal growth in rats by protecting against ischemia/reperfusion-induced oxidative/nitrosative mitochondrial damage in the placenta. J Pineal Res 2008;45:271–276.
   PubMed Web of Science ®Google Scholar
• Watanabe K, Wakatsuki A, Shinohara K, Ikenoue N, Yokota K, Fukaya T. Maternally administered melatonin protects against ischemia and reperfusion-induced oxidative mitochondrial damage in premature fetal rat brain. J Pineal Res 2004;37:276–280.
   PubMed Web of Science ®Google Scholar
• Watanabe K, Hamada F, Wakatsuki A, Nagai R, Shinohara K, Hayashi Y, Imamura R, Fukaya T. Prophylactic administration of melatonin to the mother throughout pregnancy can protect against oxidative cerebral damage in neonatal rats. J Matern Fetal Neonatal Med 2011.
   Web of Science ®Google Scholar
• Hirai N, Kawano H, Hirashima O, Motoyama T, Moriyama Y, Sakamoto T, Kugiyama K, et al. Insulin resistance and endothelial dysfunction in smokers: effects of vitamin C. Am J Physiol Heart Circ Physiol 2000;279:H1172–H1178.
   PubMed Web of Science ®Google Scholar