The effect of prenatal exposure of a non-steroidal anti-inflammatory drug on the optic nerve of female rats: a stereological, histological, and electron microscopic study

References

• Nettis E, Colanardi MC, Ferrannini A, Tursi A. Update on sensitivity to nonsteroidal antiinflammatory drugs. Curr Drug Targets Immune Endocr Metabol Disord 2001;3:233–40
   Google Scholar
• Kokki H. Nonsteroidal anti-inflammatory drugs for postoperative pain: a focus on children. Paediatr Drugs 2003;5:103–23
   PubMedGoogle Scholar
• Kudo C, Wada K, Masuda T, et al. Diclofenac inhibits proliferation and differentiation of neural stem cells. Biochem Pharmacol 2003;66:289–95
   PubMed Web of Science ®Google Scholar
• Davey PG. Overview of drug interactions with the quinolones. J Antimicrob Chemother 1988;22:97–107
   PubMedGoogle Scholar
• Segev S, Rehavi M, Rubinstein E. Quinolones, theophylline, and diclofenac interactions with the gammaaminobutyric acid receptor. Antimicrob Agents Chemother 1988;32: 1624–6
   PubMedGoogle Scholar
• Yakushiji T, Shirasaki T, Akaike N. Non-competitive inhibition of GABAA responses by a new class of quinolones and non-steroidal anti-inflammatories in dissociated frog sensory neurones. Br J Pharmacol 1992;105:13–18
   PubMedGoogle Scholar
• Vermillion ST, Scardo JA, Lashus AG, Wiles HB. The effect of indomethacin tocolysis on fetal ductus arteriosus constriction with advancing gestational age. Am J Obstet Gynecol 1997;1772:256–9
   Google Scholar
• Scholer DW, Ku EC, Boettcher I, Schweizer A. Pharmacology of diclofenac sodium. Am J Med 1986;80:34–8
   PubMed Web of Science ®Google Scholar
• Siu SSN, Yeung JHK, Lau TK. Study on placental transfer of diclofenac in first trimester of human pregnancy. Hum Reprod 2000;15:2423–5
   PubMed Web of Science ®Google Scholar
• Savaser A, Ozkan Y, Iflimer A. Preparation and in vitro evaluation of sustained release tablet formulations of diclofenac sodium. Farmaco 2005;60:171–7
   PubMedGoogle Scholar
• Alano MA, Ngougmna E, Ostrea EM Jr, Konduri GG. Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn. Pediatrics 2001;107:519–23
   PubMed Web of Science ®Google Scholar
• Chan LY, Chiu PY, Siu SS, Lau TK. A study of diclofenac-induced teratogenicity during organogenesis using a whole rat embryo culture model. Hum Reprod 2001;16:2390–3
   PubMed Web of Science ®Google Scholar
• Ostensen M. Nonsteroidal anti-inflammatory drugs during pregnancy. Scand J Rheumatol Suppl 1998;107:128–32
   PubMedGoogle Scholar
• Siu KL, Lee WH. Maternal diclofenac sodium ingestion and severe neonatal pulmonary hypertension. J Paediatr Child Health 2004;40:152–3
   PubMed Web of Science ®Google Scholar
• Liu LY, Fei XW, Li ZM, et al. Diclofenac, a nonsteroidal anti-inflammatory drug, activates the transient outward K+ current in rat cerebellar granule cells. Neuropharmacology 2005;48:918–26
   PubMed Web of Science ®Google Scholar
• Canan S, Aktas A, Ulkay MB, et al. Prenatal exposure to a non-steroidal anti-inflammatory drug or saline solution impairs sciatic nerve morphology: a stereological and histological study. Int J Devl Neuroscience 2008;26:733–8
   PubMed Web of Science ®Google Scholar
• Odaci E, Cihan OF, Aslan H, et al. Prenatal diclofenac sodium administration increases the number of Purkinje cells in female rats: a stereological study. Int J Dev Neurosci 2010;282:145–51
   Google Scholar
• Black JA, Foster RE, Waxman SG. Rat optic nerve: Freeze-fracture studies during development of myelinated axons. Brain Res 1982;250:1–20
   PubMedGoogle Scholar
• Ospina GG, Barrera AG, Larriva J, Giordano M. Insulin-like growth factor I partly prevents axon elimination in the neonate rat optic nerve. Neurosci Lett 2002;325:207–10
   PubMedGoogle Scholar
• Larsen JO. Stereology of nerve cross sections. J Neurosci Methods 1998;85:107–18
   PubMed Web of Science ®Google Scholar
• Geuna S, Tos P, Guglielmone R, et al. Methodological issues in size estimation of myelinated nerve fibers in peripheral nerves. Anat Embryol 2001;204:1–10
   PubMedGoogle Scholar
• Kaplan S, Canan S, Aslan H, et al. A simple technique to measure the movements of the microscope stage along the x and y axes for stereological methods. J Microsc 2001;203:321–5
   PubMed Web of Science ®Google Scholar
• Kaplan S, Gokyar A, Unal B, et al. A simple technique for localizing consecutive fields for disector pairs in light microscopy: application to neuron counting in rabbit spinal cord following spinal cord injury. J Neurosci Methods 2005;145:277–84
   PubMed Web of Science ®Google Scholar
• Gundersen HJ, Jensen EB, Kieu K, Nielsen J. The efficiency of systematic sampling in stereology – reconsidered. J Microsc 1999;193:199–211
   PubMed Web of Science ®Google Scholar
• Geuna S, Tos P, Battiston B, Guglielmone R. Verification of the two-dimensional disector, a method for the unbiased estimation of density and number of myelinated nerve fibers in peripheral nerves. Ann Anat 2000;182:23–34
   PubMed Web of Science ®Google Scholar
• Halliwell B, Gutteridge JM. The importance of free radicals and catalytic metal ions in human diseases. Mol Aspects Med 1985;8:89–193
   PubMed Web of Science ®Google Scholar
• Orhan H, Sahin G. In vitro effects of NSAIDS and paracetamol on oxidative stress-related parameters of human erythrocytes. Exp Toxicol Pathol 2001;53:133–40
   PubMedGoogle Scholar
• Gómez-Lechón MJ, Ponsoda X, O'Connor E, et al. Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS. Biochem Pharmacol 2003;66:2155–67
   PubMed Web of Science ®Google Scholar
• Hickey EJ, Raje RR, Reid VE, et al. Diclofenac induced in vivo nephrotoxicity may involve oxidative stress-mediated massive genomic DNA fragmentation and apoptotic cell death. Free Radic Biol Med 2001;31:139–52
   PubMed Web of Science ®Google Scholar
• Inoue A, Muranaka S, Fujita H, et al. Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, Akt, Bid, cytochrome and caspase pathway. Free Radic Biol Med 2004;37:1290–9
   PubMed Web of Science ®Google Scholar
• Milusheva E, Baranyi M, Kittel A, et al. Modulation of dopaminergic neurotransmission in rat striatum upon in vitro and in vivo diclofenac treatment. J Neurochem 2008;105:360–8
   PubMed Web of Science ®Google Scholar
• Andreasson KI, Savonenko A, Vidensky S, et al. Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice. J Neurosci 2001;21:8198–209
   PubMed Web of Science ®Google Scholar
• Cui JG, Kuroda H, Chandrasekharan NV, et al. Cyclooxygenase-3 gene expression in Alzheimer hippocampus and in stressed human neural cells. Neurochem Res 2004;29:1731–7
   PubMed Web of Science ®Google Scholar
• Trapp BD, Quarles RH. Presence of the myelin-associated glycoprotein correlates with alterations in the periodicity of peripheral myelin. J Cell Biol 1982;92:877–82
   PubMed Web of Science ®Google Scholar
• Inuzuka T, Quarles RH, Trapp BD, Heath JW. Analysis of myelin proteins in sympathetic peripheral nerve of adult rats. Brain Res 1988;466:191–9
   PubMed Web of Science ®Google Scholar
• Carp HJ, Fein A, Nebel L. Effect of diclofenac on implantation and embryonic development in the rat. Eur J Obstet Gynecol Reprod Biol 1988;28:273–7
   PubMed Web of Science ®Google Scholar
• Ragbetli MC, Ozyurt B, Aslan H, et al. Effect of prenatal exposure to diclofenac sodium on Purkinje cell numbers in rat cerebellum: a stereological study. Brain Res 2007;1174:130–5
   PubMed Web of Science ®Google Scholar
• Zengin H, Kaplan S, Tümkaya L, et al. Effect of prenatal exposure to diclofenac sodium on the male rat arteries: a stereological and histopathological study. Drug Chem Toxicol 2013;36:67–78
   PubMed Web of Science ®Google Scholar
• Ekici F, Keskin İ, Aslan H, et al. Does prenatal exposure to diclofenac sodium affect the total number of cerebellar granule cells in male juvenile and adult rats? J Exp Clin Med 2012;29: 52–7
   Google Scholar
• Ayrancı E, Altunkaynak BZ, Aktaş A, et al. Prenatal exposure of diclofenac sodium affects morphology but not axon number of the median nerve of rats. Folia Neuropathol 2013;51:76–86
   PubMed Web of Science ®Google Scholar
• Ozyurt B, Kesici H, Alıcı SK, et al. Prenatal exposure to diclofenac sodium changes the morphology of the male rat cervical spinal cord: a stereological and histopathological study. Neurotoxicol Teratol 2011;33:282–7
   PubMed Web of Science ®Google Scholar
• Güven D, Altunkaynak BZ, Ayranci E, et al. Stereological and histopathological evaluation of ovary and uterine horns of female rats prenatally exposed to diclofenac sodium. J Obstet Gynaecol 2013;33:258–63
   PubMedGoogle Scholar
• Gokcimen A, Rağbetli MC, Baş O, et al. Effect of prenatal exposure to an anti-inflammatory drug on neuron number in cornu ammonis and dentate gyrus of the rat hippocampus: a stereological study. Brain Res 2007;1127:185–92
   PubMed Web of Science ®Google Scholar