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Original Article

Canadian women’s attitudes toward noninvasive prenatal testing of fetal DNA in maternal plasma*

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Pages 4008-4014 | Received 07 Jan 2016, Accepted 05 Feb 2016, Published online: 04 Mar 2016

References

  • Gekas J, Durand A, Bujold E, et al. Cost-effectiveness and accuracy of prenatal Down syndrome screening strategies: should the combined test continue to be widely used? Am J Obstet Gynecol 2011;204:175–8.
  • Chitayat D, Langlois S, Wilson RD. Genetics Committee of the Society of Obstetricians and Gynaecologists of Canada; Prenatal Diagnosis Committee of the Canadian College of Medical Geneticists. Prenatal screening for fetal aneuploidy in singleton pregnancies. J Obstet Gynaecol Can 2011;33:736–50.
  • Mersy E, de Die-Smulders CE, Coumans AB, et al. Advantages and disadvantages of different implementation strategies of non-invasive prenatal testing in Down Syndrome Screening Programmes. Public Health Genomics 2015;18:260–71.
  • Eddleman KA, Malone FD, Sullivan L, et al. Pregnancy loss rates after midtrimester amniocentesis. J Obstet Gynaecol Surv 2007;62:163–4.
  • Benn P, Cuckle H, Pergament E. Non-invasive prenatal testing for aneuploidy: current status and future prospects. Ultrasound Obstet Gynecol 2013;42:15–33.
  • Robinson C, van den Boom D, Bombard AT. Noninvasive prenatal detection of aneuploidy. Clin Obstet Gynecol 2014;57:210–25.
  • Norton ME, Jacobsson B, Swamy GK, et al. Cell-free DNA analysis for noninvasive examination of trisomy. N Engl J Med 2015;372:1589–97.
  • De Jong A, Dondorp WJ, de Die-Smulders CE, et al. Non-invasive prenatal testing: ethical issues explored. Eur J Hum Genet 2010;18:272–7.
  • Hall A, Bostanci A, Wright CF. Non-invasive prenatal diagnosis using cell-free fetal DNA technology: applications and implications. Public Health Genomics 2010;13:246–55.
  • Benn PA, Chapman AR. Ethical challenges in providing noninvasive prenatal diagnosis. Curr Opin Obstet Gynecol 2010;22:128–34.
  • Spencer K, Aitken D. Factors affecting women's preference for type of prenatal screening test for chromosomal anomalies. Ultrasound Obstet Gynecol 2004;24:735–9.
  • Okun N, Summers AM, Hoffman B, et al. Prospective experience with integrated prenatal screening and first trimester combined screening for trisomy 21 in a large Canadian urban center. Prenat Diagn 2008;28:987–92.
  • Ontario Ministry of Health and long term care website. Available from: http://www.health.gov.on.ca/english/providers/program/child/prenatal/downsyndrome.html [last accessed 19 Feb 2015].
  • Benn PA, Chapman AR. Practical and ethical considerations of noninvasive prenatal diagnosis. JAMA 2009;301:2154–6.
  • Lench N, Barrett A, Fielding S, et al. The clinical implementation of non-invasive prenatal diagnosis for single-gene disorders: challenges and progress made. Prenat Diagn 2013;33:555–62.
  • Bowker AH. A test for symmetry in contingency tables. J Am Stat Assoc 1948;43:572–4.
  • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B 1995;57:289–300.
  • American College of Obstetricians and Gynecologists Committee on Genetics. Committee opinion no. 545: noninvasive prenatal testing for fetal aneuploidy. Obstet Gynecol 2012;120:1532–4.
  • Benn P, Borrell A, Crossley J, et al. Aneuploidy screening: a position statement from a committee on behalf of the Board of the International Society for Prenatal Diagnosis, January 2011. Prenat Diagn 2011;31:519–22.
  • Allyse M, Minear MA, Berson E, et al. Non-invasive prenatal testing: a review of international implementation and challenges. Int J Womens Health 2015;7:113–26.
  • Lewis C, Silcock C, Chitty LS. Non-invasive prenatal testing for Down's syndrome: pregnant women's views and likely uptake. Public Health Genomics 2013;16:223–32.
  • Tischler R, Hudgins L, Blumenfeld YJ, et al. Noninvasive prenatal diagnosis: pregnant women’s interest and expected uptake. Prenat Diagn 2011;26:1292–9.
  • Lewis C, Hill M, Silcock C, et al. Non-invasive prenatal testing for trisomy 21: a cross-sectional survey of service users' views and likely uptake. BJOG 2014;121:582–94.
  • Dormandy E, Michie S, Hooper R, Marteau TM. Low uptake of prenatal screening for Down syndrome in minority ethnic groups and socially deprived groups: a reflection of women's attitudes or a failure to facilitate informed choices? Int J Epidemiol 2005;34:346–52.
  • Al-Jader LN, Parry-Langdon N, Smith RJ. Survey of attitudes of pregnant women towards Down syndrome screening. Prenat Diagn 2000;20:23–9.
  • Leventhal H, Kelly K, Leventhal EA. Population risk, actual risk, perceived risk, and cancer control: a discussion. J Natl Cancer Inst Monographs 1999;25:81e5
  • Goldsmith L, Jackson L, O’Connor A, Skirton H. Direct-to-consumer genomic testing: systematic review of the literature on user perspectives. Eur J Hum Genet 2012;20:811–16.
  • Asch A. Prenatal diagnosis and selective abortion: a challenge to practice and policy. Am J Public Health 1999;89:1649–57.
  • Mahowald MB. Prenatal testing for selection against disabilities. Camb Q Healthc Ethics 2007;16:457–62. discussion 468–82.
  • Framarin A. Agence d’évaluation des technologies et des modes d’intervention en santé (AETMIS). First-trimester prenatal screening for Down syndrome and other aneuploidies (AETMIS). Montréal: AETMIS; 2003. Available from: http://www.inesss.qc.ca/publications/publications/publication/le-depistage-prenatal-du-syndrome-de-down-et-dautres-aneuploidies-au-premier-trimestre-de-la-g.html [last accessed Apr. 2015].
  • Dondorp W, de Wert G, Bombard Y, et al. Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening. Eur J Hum Genet 2015;23:1438–50.

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