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Research Article

TNF-α inhibition using etanercept prevents noise-induced hearing loss by improvement of cochlear blood flow in vivo

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Pages 545-552 | Received 26 Aug 2012, Accepted 15 Mar 2013, Published online: 20 Jun 2013

References

  • Arpornchayanon W., Canis M., Suckfuell M., Ihler F., Olzowy B. et al. 2011. Modeling the measurements of cochlear microcirculation and hearing function after loud noise. Otolaryngol Head Neck Surg, 145, 463–469.
  • Baker M. & Wayland H. 1974. On-line flow rate and velocity profile measurement for blood in microvessels. Microvasc Res, 7, 131–143.
  • Canis M., Arpornchayanon W., Messmer C., Suckfuell M., Olzowy B. et al. 2010. An animal model for the analysis of cochlear blood flow (corrected) disturbance and hearing threshold in vivo. Eur Arch Otorhinolaryngol, 267, 197–203.
  • Cohen S., Shoup A., Weisman M.H. & Harris J. 2005. Etanercept treatment for autoimmune inner ear disease: Results of a pilot placebo-controlled study. Otol Neurotol, 26, 903–907.
  • Dai M., Nuttall A., Yang Y. & Shi X. 2009. Visualization and contractile activity of cochlear pericytes in the capillaries of the spiral ligament. Hear Res, 254, 100–107.
  • Fichtlscherer S., Rossig L., Breuer S., Vasa M., Dimmeler S. et al. 2001. Tumor necrosis factor antagonism with etanercept improves systemic endothelial vasoreactivity in patients with advanced heart failure. Circulation, 104, 3023–3025.
  • Fujioka M., Kanzaki S., Okano H.J., Masuda M., Ogawa K. et al. 2006. Proinflammatory cytokines expression in noise-induced damaged cochlea. J Neurosci Res, 83, 575–583.
  • Heinrich U.R., Selivanova O., Schmidtmann I., Feltens R., Brieger J. et al. 2010. Noise exposure alters cyclooxygenase 1 (COX-1) and 5-lipoxygenase (5-LO) expression in the guinea pig cochlea. Acta Otolaryngol, 130, 358–365.
  • Henderson D., Bielefeld E.C., Harris K.C. & Hu B.H. 2006. The role of oxidative stress in noise-induced hearing loss. Ear Hear, 27, 1–19.
  • Hurlimann D., Forster A., Noll G., Enseleit F., Chenevard R. et al. 2002. Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis. Circulation, 106, 2184–2187.
  • Ihler F., Sharaf K.,Bertlich M.,Strieth S.,Reichel C.A. et al. Etanercept prevents decrease of cochlear blood flow dose-dependently caused by Tumor Necrosis Factor-alpha.Ann Otol Rhinol Laryngol, in press.
  • Keithley E.M., Wang X. & Barkdull G.C. 2008. Tumor necrosis factor alpha can induce recruitment of inflammatory cells to the cochlea. Otol Neurotol, 29, 854–859.
  • Kim D.H., Park Y.S., Jeon E.J., Yeo S.W., Chang K.H. et al. 2006. Effects of tumor necrosis factor alpha antagonist, platelet activating factor antagonist, and nitric oxide synthase inhibitor on experimental otitis media with effusion. Ann Otol Rhinol Laryngol, 115, 617–623.
  • Klyscz T., Jünger M., Jung F. & Zeintl H. 1997. Cap image: A new kind of computer-assisted video image analysis system for dynamic capillary microscopy. Biomed Tech Berl, 42, 168–175.
  • Kono M., Belyantseva I.A., Skoura A., Frolenkov G.I., Starost M.F. et al. 2007. Deafness and stria vascularis defects in S1P2 receptor-null mice. J Biol Chem, 282, 10690–10696.
  • Le Prell C.G., Yamashita D., Minami S.B., Yamasoba T. & Miller J.M. 2007. Mechanisms of noise-induced hearing loss indicate multiple methods of prevention. Hear Res, 226, 22–43.
  • Lobo D., Trinidad A., Garcia-Berrocal J.R., Verdaguer J.M. & Ramirez- Camacho R. 2006. TNFalpha blockers do not improve the hearing recovery obtained with glucocorticoid therapy in an autoimmune experimental labyrinthitis. Eur Arch Otorhinolaryngol, 263, 622–626.
  • Matteson E.L., Choi H.K., Poe D.S., Wise C., Lowe V.J. et al. 2005. Etanercept therapy for immune-mediated cochleovestibular disorders: A multi-center, open-label, pilot study. Arthritis Rheum, 53, 337–342.
  • Miller J.M., Brown J.N. & Schacht J. 2003. 8-iso-prostaglandin F(2alpha), a product of noise exposure, reduces inner ear blood flow. Audiol Neurootol, 8, 207–221.
  • Nakai Y. & Masutani H. 1988. Noise-induced vasoconstriction in the cochlea. Acta Otolaryngol Suppl, 447, 23–27.
  • Nuttall A.L. 1987. Techniques for the observation and measurement of red blood cell velocity in vessels of the guinea pig cochlea. Hear Res, 27, 111–119.
  • Nuttall A.L. 1987. Velocity of red blood cell flow in capillaries of the guinea pig cochlea. Hear Res, 27, 121–128.
  • Nuttall A.L. 1999. Sound-induced Cochlear ischemia/hypoxia as a mechanism of hearing loss. Noise Health, 2, 17–32.
  • Psillas G., Pavlidis P., Karvelis I., Kekes G., Vital V. et al. 2008. Potential efficacy of early treatment of acute acoustic trauma with steroids and piracetam after gunshot noise. Eur Arch Otorhinolaryngol, 265, 1465–1469.
  • Satoh H., Firestein G.S., Billings P.B., Harris J.P. & Keithley E.M. 2002. Tumor necrosis factor-alpha, an initiator, and etanercept, an inhibitor of cochlear inflammation. Laryngoscope, 112, 1627–1634.
  • Scherer E.Q., Lidington D., Oestreicher E., Arnold W., Pohl U. et al. 2006. Sphingosine-1-phosphate modulates spiral modiolar artery tone: A potential role in vascular-based inner ear pathologies?Cardiovasc Res, 70, 79–87.
  • Scherer E.Q., Yang J., Canis M., Reimann K., Ivanov K. et al. 2010. Tumor necrosis factor-alpha enhances microvascular tone and reduces blood flow in the cochlea via enhanced sphingosine-1-phosphate signaling. Stroke, 41, 2618–2624.
  • Shi X. 2009. Cochlear pericyte responses to acoustic trauma and the involvement of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Am J Pathol, 174, 1692–1704.
  • Shi X. 2011. Physiopathology of the cochlear microcirculation. Hear Res, 282, 10–24.
  • Tabuchi K., Murashita H., Sakai S., Hoshino T., Uemaetomari I. et al. 2006. Therapeutic time window of methylprednisolone in acoustic injury. Otol Neurotol, 27, 1176–1179.
  • Thalmann R., Miyoshi T. & Thalmann I. 1972. The influence of ischemia upon the energy reserves of inner ear tissues. Laryngoscope, 82, 2249–2272.
  • Tornabene S.V., Sato K., Pham L., Billings P. & Keithley E.M. 2006. Immune cell recruitment following acoustic trauma. Hear Res, 222, 115–124.
  • Wang X., Truong T., Billings P.B., Harris J.P. & Keithley E.M. 2003. Blockage of immune-mediated inner-ear damage by etanercept. Otol Neurotol, 24, 52–57.
  • Zeintl H., Sack F.U., Intaglietta M. & Messmer K. 1989. Computer assisted leukocyte adhesion measurement in intravital microscopy. Int J Microcirc Clin Exp, 8, 293–302.

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