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Journal of Pain & Palliative Care Pharmacotherapy Volume 25, 2011 - Issue 4
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REPORTS

Transitioning a Cancer Patient From High-Dose Intravenous Hydromorphone Therapy to Intravenous Methadone

Virginia LeBaron At the time of manuscript acceptance, Virginia LeBaron was with the University of Arizona College of Nursing and University Medical Center, Tucson, Arizona. She is now a PhD candidate at the University of Utah College of Nursing; Jacqueline Brody, PharmD, is with the University Medical Center, Tucson, Arizona; Ellyn M. Lee is with the University of Arizona, Tucson, Arizona; Cleo Hardin, MD, and Linda Snyder, MD, FCCP, are with the University of Arizona, Tucson, ArizonaCorrespondence[email protected]
,
Jacqueline Brody At the time of manuscript acceptance, Virginia LeBaron was with the University of Arizona College of Nursing and University Medical Center, Tucson, Arizona. She is now a PhD candidate at the University of Utah College of Nursing; Jacqueline Brody, PharmD, is with the University Medical Center, Tucson, Arizona; Ellyn M. Lee is with the University of Arizona, Tucson, Arizona; Cleo Hardin, MD, and Linda Snyder, MD, FCCP, are with the University of Arizona, Tucson, Arizona
,
Ellyn M. Lee At the time of manuscript acceptance, Virginia LeBaron was with the University of Arizona College of Nursing and University Medical Center, Tucson, Arizona. She is now a PhD candidate at the University of Utah College of Nursing; Jacqueline Brody, PharmD, is with the University Medical Center, Tucson, Arizona; Ellyn M. Lee is with the University of Arizona, Tucson, Arizona; Cleo Hardin, MD, and Linda Snyder, MD, FCCP, are with the University of Arizona, Tucson, Arizona
,
Cleo Hardin At the time of manuscript acceptance, Virginia LeBaron was with the University of Arizona College of Nursing and University Medical Center, Tucson, Arizona. She is now a PhD candidate at the University of Utah College of Nursing; Jacqueline Brody, PharmD, is with the University Medical Center, Tucson, Arizona; Ellyn M. Lee is with the University of Arizona, Tucson, Arizona; Cleo Hardin, MD, and Linda Snyder, MD, FCCP, are with the University of Arizona, Tucson, Arizona
&
Linda Snyder At the time of manuscript acceptance, Virginia LeBaron was with the University of Arizona College of Nursing and University Medical Center, Tucson, Arizona. She is now a PhD candidate at the University of Utah College of Nursing; Jacqueline Brody, PharmD, is with the University Medical Center, Tucson, Arizona; Ellyn M. Lee is with the University of Arizona, Tucson, Arizona; Cleo Hardin, MD, and Linda Snyder, MD, FCCP, are with the University of Arizona, Tucson, Arizona
Pages 356-361 | Published online: 29 Nov 2011

REFERENCES

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  • Manfreidi, PL, Borsook D, Chandler SW, Payne, R. Intravenous methadone for cancer pain unrelieved by morphine and hydromorphone: clinical observations. Pain. 1997;70:99–101.
  • Ripamonti C, Bianchi M. The use of methadone for cancer pain. Hematol Oncol Clin N Am. 2002;16:543–555.
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  • Pollock AB, Tegeler ML, Morgan V, Baumrucker SJ. Morphine to methadone conversion: an interpretation of published data. Am J Hosp Palliat Care. 2011;28:135–140.
  • Fine PG, Portenoy RK. Establishing ‘best practices’ for opioid rotation: conclusions of an expert panel. J Pain Symptom Manage. 2009;38:418–425.
  • Thomas Z, Bruera E. Use of methadone in a highly tolerant patient receiving parenteral hydromorphone. J Pain Symptom Manage. 1995;10:315–317.
  • American Pain Society. Principles of Analgesic Use in the Treatment of Acute Pain and Cancer Pain. 6th ed. Glenview, IL: American Pain Society; 2008:41–47.
  • McPherson ML. Methadone: a complex and challenging analgesic, but it's worth it (Chapter 6, pp. 107–143) and patient controlled analgesia (Chapter 7, 145–166). In: McPherson ML, ed. Demystifying Opioid Conversion Calculations: A Guide for Effective Dosing. Bethesda, MD: American Society of Health-Systems Pharmacists; 2010.

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