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Journal of Pain & Palliative Care Pharmacotherapy Volume 27, 2013 - Issue 2
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CASE REPORT

Oral Ketamine for Sickle Cell Crisis Pain Refractory to Opioids

Cara A. Jennings Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.Correspondence[email protected]
,
Barton T. Bobb Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.
,
Danielle M. Noreika Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.
&
Patrick J. Coyne Cara A. Jennings, MD, is a fellow; Barton T. Bobb, MSN, FNP-BC, ACHPN, is an advanced practice nurse; Danielle M. Noreika, MD, is an assistant clinical professor in the Division of Hematology, Oncology and Palliative Care, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA; Patrick J. Coyne, MSN, APRN, FAAN, is Clinical Director, Pain and Palliative Care, Thomas Palliative Care Services, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.
Pages 150-154 | Received 27 Feb 2013, Accepted 13 Mar 2013, Published online: 21 May 2013

REFERENCES

  • White PF, Way WL, Trevor AJ. Ketamine—its pharmacology and therapeutic uses. Anesthesiology. 1982;56:119–136.
  • Anis NA, Berry SC, Burton NR, Lodge D. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. Br J Pharmacol. 1983;79:565–575.
  • Visser E, Schug SA. The role of ketamine in pain management. Biomed Pharmacother. 2006;60:341–348.
  • Fisher K, Coderre TJ, Hagen NA. Targeting the N-methyl-d-aspartate receptor for chronic pain management. Preclinical animal studies, recent clinical experience and future research directions. J Pain Symptom Manage. 2000;20:358–373.
  • Okon T. Ketamine: an introduction for the pain and palliative medicine physician. Pain Physician. 2007;10:493–500.
  • Subramaniam K, Subramaniam B, Steinbrook RA. Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review. Anesth Analg. 2004;99:482–495.
  • Bell RF, Eccleston C, Kalso EA. Ketamine as an adjuvant to opioids for cancer pain. Cochrane Database Syst Rev. 2012;(11):CD003351.
  • Cvrcek P. Side effects of ketamine in the long-term treatment of neuropathic pain. Pain Med. 2008;9:253–257.
  • Hewitt DJ. The use of NMDA-receptor antagonists in the treatment of chronic pain. Clin J Pain. 2000;16( 2 Suppl): S73–S79.
  • Kannan TR, Saxena A, Bhatnagar S, Barry A. Oral ketamine as an adjuvant to oral morphine for neuropathic pain in cancer patients. J Pain Symptom Manage. 2002;23:60–65.
  • McCartney CJ, Sinha A, Katz J. A qualitative systematic review of the role of N-methyl-d-aspartate receptor antagonists in preventive analgesia. Anesth Analg. 2004;98:1385–1400.
  • Ballas SK. Sickle cell disease: clinical management. Baillieres Clin Haematol. 1998;11:185–214.
  • Ballas SK, Gupta K, Adams-Graves P. Sickle cell pain: a critical reappraisal. Blood. 2012;120:3647–3656. doi: 10.1182/blood-2012–04–383430.
  • Dunlop RJ, Bennett KC. Pain management for sickle cell disease. Cochrane Database Syst Rev. 2006;(2):CD003350.
  • Elander J, Midence K. A review of evidence about factors affecting quality of pain management in sickle cell disease. Clin J Pain. 1996;12:180–193.
  • Niscola P, Sorrentino F, Scaramucci L, de Fabritiis P, Cianciulli P. Pain syndromes in sickle cell disease: an update. Pain Med. 2009;10:470–480.
  • Zempsky WT, Loiselle KA, Corsi JM, Hagstrom JN. Use of low-dose ketamine infusion for pediatric patients with sickle cell disease-related pain: a case series. Clin J Pain. 2010;26: 163–167.
  • Meals CG, Mullican BD, Shaffer CM, Dangerfield PF, Ramirez RP. Ketamine infusion for sickle cell crisis pain in an adult. J Pain Symptom Manage. 2011;42:e7–e9.
  • Kotlińska-Lemieszek A, Luczak J. Subanesthetic ketamine: an essential adjuvant for intractable cancer pain. J Pain Symptom Manage. 2004;28:100–102.
  • Mercadante S, Arcuri E, Tirelli W, Casuccio A. Analgesic effect of intravenous ketamine in cancer patients on morphine therapy: a randomized, controlled, double-blind, crossover, double-dose study. J Pain Symptom Manage. 2000;20:246–252.
  • Azari P, Lindsay DR, Briones D, Clarke C, Buchheit T, Pyati S. Efficacy and safety of ketamine in patients with complex regional pain syndrome: a systematic review. CNS Drugs. 2012;26:215–228.
  • Correll GE, Maleki J, Gracely EJ, Muir JJ, Harbut RE. Subanesthetic ketamine infusion therapy: a retrospective analysis of a novel therapeutic approach to complex regional pain syndrome. Pain Med. 2004;5:263–275.
  • Willetts J, Balster RL, Leander JD. The behavioral pharmacology of NMDA receptor antagonists. Trends Pharmacol Sci. 1990;11:423–428.
  • Shahani R, Streutker C, Dickson B, Stewart RJ. Ketamine-associated ulcerative cystitis: a new clinical entity. Urology. 2007;69:810–812.
  • Winstock AR, The prevalence and natural history of urinary symptoms among recreational ketamine users. BJU Int. 2012;110 (11):1762–1766.

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