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Research Article

Acquired multidrug resistance in human K562/ADM cells is associated with enhanced autophagy

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Pages 678-683 | Received 01 Apr 2013, Accepted 12 Aug 2013, Published online: 08 Oct 2013

References

  • Ahn JH, Lee M. (2011). Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2. Cancer Lett 310:188–97
  • Amaravadi RK, Yu D, Lum JJ, et al. (2007). Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. Clin Invest 117:326–36
  • Apel A, Herr I, Schwarz H, et al. (2008). Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res 68:1485–94
  • Bellodi C, Lidonnici MR, Hamilton A, et al. (2009). Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 119:1109–23
  • Chen YJ, Huang WP, Yang YC, et al. (2009). Platonin induces autophagy-associated cell death in human leukemia cells. Autophagy 5:173–83
  • Hoyer-Hansen M, Bastholm L, Mathiasen S, et al. (2005). Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin1-mediated autophagic cell death. Cell Death Differ 12:1297–309
  • Isakson P, Bjoras M, Boe SO, et al. (2010). Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein. Blood 116:2324–31
  • Kabeya Y, Mizushima N, Ueno T, et al. (2000). LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19:5720–8
  • Kim DH, Lee NY, Sung WJ, et al. (2005). Multidrug resistance as a potential prognostic indicator in acute myeloid leukemia with normal karyotypes. Acta Haematol 114:78–83
  • Kim KW, Hwang M, Moretti L, et al. (2008). Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy 4:659–68
  • Koistinen P, Raty R, Itala M, et al. (2007). Long-term outcome of intensive chemotherapy for adults with de novo acute myeloid leukaemia (AML): the nationwide AML-92 study by the Finnish Leukaemia Group. Eur J Haematol 78:477–86
  • Kondo Y, Kanzawa T, Sawaya R, et al. (2005). The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5:726–34
  • Kong D, Ma S, Liang B, et al. (2012). The different regulatory effects of p53 status on multidrug resistance are determined by autophagy in ovarian cancer cells. Biomed Pharmacother 66:271–8
  • Levine B, Kroemer G. (2008). Autophagy in the pathogenesis of disease. Cell 11:27–42
  • Martinet W, De Meyer GR, Andries L, et al. (2006). In situ detection of starvation-induced autophagy. J Histochem Cytochem 54:85–96
  • Mathew R, Karantza V, White E. (2007). Role of autophagy in cancer. Nat Rev Cancer 7:961–7
  • Mi Y, Xue Y, Yu W, et al. (2008). Therapeutic experience of adult acute myeloid leukemia in a single institution of China and its relationship with chromosome karyotype. Leuk Lymphoma 49:524–30
  • Mizushima N. (2004). Methods for monitoring autophagy. Int J Biochem Cell Biol 36:2491–502
  • Mortensen M, Watson AS, Simon AK. (2011). Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation. Autophagy 7:1069–70
  • Pirker R, Wallner J, Geissler K, et al. (1991). MDR1 gene expression and treatment outcome in acute myeloid leukemia. J Natl Cancer Inst 83:708–12
  • Qian WB, Liu JQ, Jin J. (2007). Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1. Leukemia Res 31:329–39
  • Ren JH, He WS, Nong L, et al. (2010). Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. Cancer Biother Radiopharm 25:75–80
  • Song J, Qu Z, Guo X, et al. (2009). Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells. Autophagy 5:1131–44
  • Stavrovskaya AA. (2000). Cellular mechanisms of multidrug resistance of tumor cells. Biochemistry (Mosc) 65:95–106
  • Stone RM, O'Donnell MR, Sekeres MA. (2004). Acute myeloid leukemia. Hematol Am Soc Hematol Educ Program 2004:98–117
  • Talloczy Z, Jiang W, Virgin HW, et al. (2002). Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci 99:190–5
  • Trocoli A, Mathieu J, Priault M, et al. (2011). ATRA-induced upregulation of Beclin-1 prolongs the life span of differentiated acute promyelocytic leukemia cells. Autophagy 7:1108–14
  • Wei H, Su H, Bai D, et al. (2003). Arsenic trioxide inhibits p-glycoprotein expression in multidrug-resistant human leukemia cells that overexpress the MDR1 gene. Chin Med J (Engl) 116:1644–8
  • Yang C, Kaushal V, Shah SV, et al. (2008). Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. Am J Physiol Renal Physiol 294:777–87
  • Yang L, Yang M, Zhang H, et al. (2012). S100A8-targeting siRNA enhances arsenic trioxide-induced myeloid leukemia cell death by down-regulating autophagy. Int J Mol Med 29:65–72
  • Zhang JQ, Li YM, Liu T, et al. (2010). Antitumor effect of matrine in human hepatoma G2 cells by inducing apoptosis and autophagy. World J Gastroenterol 16:4281–90
  • Zhang SP, Niu YN, Yuan N, et al. (2012). Role of autophagy in acute myeloid leukemia therapy. Chin J Cancer 32:130--5

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