References
- Abarikwu SO, Farombi EO, Kashyap MP, Pant AB. (2011). Kolaviron protects apoptotic cell death in PC12 cells exposed to Atrazine. Free Radic Res 45:1061–73
- Abdelaziz I, Elhabiby MI, Ashour AA. (2013). Toxicity of cadmium and protective effect of bee honey, vitamins C and B complex. Hum Exp Toxicol 32:362–70
- Adedara IA, Farombi EO. (2012). Chemoprotection of ethylene glycol monoethyl ether-induced reproductive toxicity in male rats by kolaviron – an isolated biflavonoid from Garcinia kola seeds. Hum Exp Toxicol 31:506–17
- Adedara IA, Mathur PP, Farombi EO. (2013). Kolaviron prevents ethylene glycol monoethyl ether-induced testicular apoptosis via down-regulation of stress proteins, Fas/Fas-L and caspases expressions in rats. Toxicol Mech Meth 23:689–96
- Afifi AK, Bergman RA. (2005). Functional neuroanatomy text and atlas. 2nd ed. New York: McGraw-Hill
- Aloisi AM, Zimmermann M, Herdegen T. (1997). Sex-dependent effects of formalin and restraint on c-Fos expression in the septum and hippocampus of the rat. Neuroscience 81:951–8
- Bancroft JD, Gamble M. (2008). Theory and practice of histology techniques. 6th ed. Philadelphia (PA): Churchill Livingstone Elsevier
- Bast A, Barr PR. (1997). The antioxidant/prooxidant balance in neurodegeneration. In: Bar PR, Beal MF, eds. Neuroprotection in CNS diseases. New York: Marcel Deccer Inc., 147–59
- Bhuller Y, Jeng W, Wells PG. (2006). Variable in vivo embryoprotective role for ataxia-telangiectasia-mutated against constitutive and phenytoin-enhanced oxidative stress in atm knockout mice. Toxicol Sci 93:146–55
- Blinkov SM, Gleezer T. (1968). The human brain in figures and tables: a quantitative handbook. New York: Plenum
- Cadenas E, Packer L. (2001). Handbook of antioxidants. Revised and Expanded. 2nd ed. NewYork: Marcel Dekker Inc
- Clairborne A. (1995). Catalase activity. In: Greewald AR, ed. Handbook of methods for oxygen radical research. Boca Raton (FL): CRC Press, 237–42
- Cowell RA, Bussey TJ, Saksida LM. (2010). Components of recognition memory: dissociable cognitive processes or just differences in representational complexity? Hippocampus 20:1245–62
- De Franceschi L, Bertoldi M, De Falco L, et al. (2011). Oxidative stress modulates heme synthesis and induces peroxiredoxin-2 as a novel cytoprotective response in β-thalassemic erythropoiesis. Haematologica 96:1595–604
- Dosch HM, Jason J, Gelfand EW. (1982). Transient antibody deficiency and abnormal T suppressor cells induced by phenytoin. N Engl J Med 306:406
- Ebert U, Cramer S, Löscher W. (1997). Phenytoin's effect on the spread of seizure activity in the amygdala kindling model. Naunyn Schmiedebergs Arch Pharmacol 356:341–7
- Ebokaiwe AP, Adedara IA, Owoeye O, Farombi EO. (2013). Neurotoxicity of Nigerian bonny light crude oil in rats. Drug Chem Toxicol 39:187–95
- Erenberk U, Dundaroz R, Gok O, et al. (2014). Melatonin attenuates phenytoin sodium-induced DNA damage. Drug Chem Toxicol 37:233–9
- Farombi EO, Akanni OO, Emerole GO. (2002). Antioxidative and scavenging activities of kolaviron in vitro. Pharm Biol 40:107–16
- Farombi EO, Tahnteng JG, Agboola AO, et al. (2000). Chemoprevention of 2-acetylaminofluorene-induced hepatotoxicity and lipid peroxidation in rats by kolaviron – a Garcinia kola seed extract. Food Chem Toxicol 38:535–41
- Farombi EO, Adedara IA, Ajayi BO, et al. (2013). Kolaviron, a natural antioxidant and anti-inflammatory phytochemical prevents dextran sulphate sodium-induced colitis in rats. Basic Clin Pharmacol Toxicol 113:49–55
- Gaustaut H. (1973). Dictionary of epilepsy I. Definitions. Geneva: WHO
- Iwu MM. (1985). Antihepatoxic constituents of Garcinia kola seeds. Experientia 41:699–700
- Jerina DA, Daly JW. (1974). Arene oxides: a new aspect of drug metabolism. Science 85:573–82
- Johnson-Delaney C. (1996). Exotic animal companion medicine handbook for veterinarians. Lake Worth (FL): Zoological Education Network, 1–15
- Jollow DJ, Mitchell JR, Zampaglione N, Gillette JR. (1974). Bromobenzene induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology 11:151–69
- Katz I, Kim J, Gale K, Kondratyev A. (2007). Effects of lamotrigine alone and in combination with mk-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain. J Pharmacol Exp Ther 322:494–500
- Leppik IE and Epilepsy Foundation of America (EFA). (2005). Choosing an antiepileptic. Selecting drugs for older patients with epilepsy. Geriatrics 60:42–7
- Liu CS, Wu HM, Kao SH, Wei YH. (1997). Phenytoin-mediated oxidative stress in serum of female epileptics: a possible pathogenesis in the fetal hydantoin syndrome. Hum Exp Toxicol 16:177–81
- Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with folin phenol reagent. J Biol Chem 193:265–75
- Luef G, Chemelli A, Birbamer G, et al. (1994). Phenytoin overdosage and cerebellar atrophy in epileptic patients: clinical and MRI findings. Eur Neurol 34:79–81
- Mahle C, Dasgupta A. (1997). Decreased total antioxidant capacity and elevated lipid hydroperoxide concentrations in sera of epileptic patients receiving phenytoin. Life Sci 61:437–43
- Masaki H, Okano Y, Sakurai H. (1998). Differential role of catalase and glutathione peroxidase in cultured human fibroblasts under exposure of H2O2 or ultraviolet B light. Arch Dermatolog Res 290:113–18
- McNamara JO. (2006). Pharmacotherapy of the epilepsies. In: Bruton LL, Lazo JS, Parker KJ, eds. Goodman and Gilman's the pharmacological basis of therapeutics. 11th ed. New York: Mc Graw-Hill, 501–25
- Misra HP, Fridovich I. (1972). The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247:3170–5
- Navarova J, Ujhazy E, Dubovicky D, Mach M. (2005). Phenytoin induced oxidative stress in pre- and postnatal rat development – effect of vitamin E on selective biochemical variables. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 149:325–8
- Ohmori H, Kobayashi T, Yasuda M. (1992). Neurotoxicity of phenytoin administered to newborn mice on developing cerebellum. Neurotoxicol Teratol 14:159–65
- Okamoto Y, Shimizu K, Tamura Y, et al. (1988). Effects of phenytoin on cell-mediated immunity. Cancer Immunol Immunother 26:176–9
- Olaleye SB, Farombi EO, Adewoye EA, et al. (2000). Analgesic and anti-inflammatory effects of kolaviron (a Garcinia kola seed extract). Afr J Biomed Res 3:171–4
- Olsen RK, Moses SN, Riggs L, Ryan JD. (2012). The hippocampus supports multiple cognitive processes through relational binding and comparison. Front Hum Neurosci 146:1–12
- Olubunmi AO. (2006). Epilepsy in Nigeria – a review of etiology, epidemiology. Benin J Postgraduate Med 8:27–51
- Ono H, Sakamoto A, Sakura N. (2000). Plasma total glutathione concentrations in epileptic patients taking anticonvulsants. Clin Chim Acta 298:135–43
- Osuagwu FC, Owoeye O, Avwioro OG, et al. (2007). Reduction of hippocampal CA 1 neurons in Wistar rats following the administration of phenytoin for seven days. Afr J Med Med Sci 36:103–8
- Owoeye O, Farombi EO, Onwuka SK. (2010). Cerebellar reduction in rats by gamma irradiation is mitigated by pretreatment with methanolic extract of Vernonia amygdalina and alpha-tocopherol. Eur J Anat 14:49–58
- Oyagbemi AA, Adedara IA, Saba AB, Farombi EO. (2010). Role of oxidative stress in reproductive toxicity induced by co-administration of chloramphenicol and multivitamin-haematinics complex in rats. Basic Clin Pharmacol Toxicol 107:703–8
- Papas AM. (1999). Other antioxidants. In: Papas AM, ed. Antioxidant status, diet, nutrition, and health. Boca Raton (FL): CRC Press, 231–48
- Public Health Service. (1996). Public health service policy on humane care and use of laboratory animals. Washington, DC: US Department of Health and Human Services
- Rall TW, Schleifer LS. (1990). Hydantoins. In: Goodman Gilman A, Rall TW, Nies AS, Taylor P, eds. Pharmacological basis of therapeutics. New York: Pergamon Press, 439–44
- Ravishankar D, Nithya G, Vidya K, et al. (2004). In-vitro lymphocyte toxicity to a phenytoin metabolite in phenytoin induced cutaneous adverse drug eruptions. Indian J Dermatol Venereol Leprol 70:217–20
- Rawanduzy A, Sarkis A, Rovit RL. (1993). Severe phenytoin-induced bone marrow depression and agranulocytosis treated with human recombinant granulocyte-macrophage colony-stimulating factor case report. J Neurosurg 79:121–4
- Rocha JBT, Saraiva RA, Garcia SC, et al. (2012). Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations. Toxicol Res 1:85–102
- Rotruck JT, Pope AL, Ganther HE, et al. (1973). Selenium: biochemical role as a component of glutathione peroxidase. Science 179:588–90
- Santhrani T, Puspha B. (2007). Influence of spirulina on the phenytoin induced haematological changes. Ancient Sci Life 26:9–15
- Scott DL, Kelleher J, Losowsky MS. (1977). The influence of dietary selenium and vitamin E on glutathione peroxidase and glutathione in the rat. Biochim Biophys Acta 497:218–24
- Shapiro ML, Eichenbaum H. (1999). Hippocampus as a memory map: synaptic plasticity and memory encoding by hippocampal neurons. Hippocampus 9:365–84
- Singh I. (2007). Atlas of human anatomy. New Delhi: Jay Pee Publishers, 367–77
- Songur A, Akpolat N, Kus I, et al. (2003). The effects of the inhaled formaldehyde during the early postnatal period in the hippocampus of rats: a morphological and immunohistochemical study. Neurosci Res Commun 33:168–78
- Sugihara I, Bailly Y, Mariana J. (2000). Olivocerebellar climbing fibers in the granuloprival cerebellum: morphological study of individual axonal projections in the X-irradiated rat. J Neurosci 20:3745–60
- Susumu I, Mutsuki S, Kaori S, et al. (2009). Agranulocytosis following phenytoin-induced hypersensitivity syndrome. Brain Dev 31:449–51
- Terashima K, Takawa Y, Niwa M. (2002). Powerful antioxidative agents based on garcinoic acid from Garcinia kola. Bioorg Med Chem 10:1619–25
- Winn LM, Kim PM, Nickoloff JA. (2003). Oxidative stress-induced homologous recombination as a novel mechanism for phenytoin-initiated toxicity. J Pharmacol Exp Ther 306:523–37
- Wolff SP. (1994). Ferrous ion oxidation in the presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Methods Enzymol 233:182–9
- Wyss JM, Groen TV. (1995). The Limbic system. In: Conn PM, ed. Neuroscience in medicine. Philadelphia: JB Lippincott Company, 321–42
- Yorulmaz H, Burcu Seker F, Oztas B. (2011). Effect of vitamin E on blood-brain barrier permeability in aged rats with PTZ-induced convulsions. Neurophysiology 42:349–53