N-acetylcysteine does not protect behavioral and biochemical toxicological effect after acute exposure of diphenyl ditelluride

References

• Aebi H. (1984). Catalase in vitro. Methods Enzymol 105:121–6
   PubMed Web of Science ®Google Scholar
• Atkuri KR, Mantovani JJ, Herzenberg LA, Herzenberg LA. (2007). N-Acetylcysteine – a safe antidote for cysteine/glutathione deficiency. Curr Opin Pharmacol 7:355–9
   PubMed Web of Science ®Google Scholar
• Avila DS, Benedetto A, Au C, et al. (2012). Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress. Free Radic Biol Med 52:1903–10
   PubMed Web of Science ®Google Scholar
• Ávila DS, Colle D, Gubert P, et al. (2010). A possible neuroprotective action of a vinylic telluride against Mn-induced neurotoxicity. Toxicol Sci 115:194–201
   PubMed Web of Science ®Google Scholar
• Ávila DS, Palma AS, Colle D, et al. (2011). Hepatoprotective activity of a vinylic telluride against acute exposure to acetaminophen. Eur J Pharmacol 661:92–101
   PubMed Web of Science ®Google Scholar
• Borges VC, Rocha JBT, Nogueira CW. (2005). Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na+K+ ATPase activity in rats. Toxicology 215:191–7
   PubMed Web of Science ®Google Scholar
• Brito VB, Rocha JB, Folmer V, Erthal F. (2009). Diphenyl diselenide and diphenyl ditelluride increase the latency for 4-aminopyridine-induced chemical seizure and prevent death in mice. Acta Biochim Pol 56:125–34
   PubMed Web of Science ®Google Scholar
• Caeran Bueno D, Meinerz DF, Allebrandt J, et al. (2013). Cytotoxicity and genotoxicity evaluation of organochalcogens in human leucocytes: a comparative study between ebselen, diphenyl diselenide, and diphenyl ditelluride. Biomed Res Int 2013, ID 537279, 6 pages. doi:10.1155/2013/537279
   Google Scholar
• Calberg I, Mannervik B. (1985). Glutathione reductase. Methods Enzymol 113:484–90
   PubMed Web of Science ®Google Scholar
• Chasteen TG, Fuentes DE, Tantaleán JC, Vásquez CC. (2009). Tellurite: history, oxidative stress, and molecular mechanisms of resistance. FEMS Microbiol Rev 33:820–32
   PubMed Web of Science ®Google Scholar
• Chen F, Vallyathan V, Castranova V, Shi X. (2001). Cell apoptosis induced by carcinogenic metals. Mol Cell Biochem 221:183–8
   Web of Science ®Google Scholar
• Comparsi B, Meinerz DF, Franco JL, et al. (2012). Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure. Mol Cell Biochem 370:173–82
   PubMed Web of Science ®Google Scholar
• Cunha RL, Gouvea IE, Juliano L. (2009). A glimpse on biological activities of tellurium compounds. An Acad Bras Cienc 81:393–407
   PubMed Web of Science ®Google Scholar
• Cunha RL, Urano ME, Chagas JR, et al. (2005). Tellurium-based cysteine protease inhibitors: evaluation of novel organotellurium(IV) compounds as inhibitors of human cathepsin B. Bioorg Med Chem Lett 15:755–60
   PubMed Web of Science ®Google Scholar
• de Andrade RB, Gemelli T, Guerra RB, et al. (2012). Kinetic studies on the inhibition of creatine kinase activity by 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one in the cerebral cortex of rats. Food Chem Toxicol 50:3468–74
   PubMed Web of Science ®Google Scholar
• De Avila DS, Beque MC, Folmer V, et al. (2006). Diethyl 2-phenyl-2 tellurophenyl vinylphosphonate: an organotellurium compound with low toxicity. Toxicology 224:100–7
   PubMed Web of Science ®Google Scholar
• Degrandi TH, de Oliveira IM, D'almeida GS, et al. (2010). Evaluation of the cytotoxicity, genotoxicity and mutagenicity of diphenyl ditelluride in several biological models. Mutagenesis 25:257–69
   PubMed Web of Science ®Google Scholar
• Doering M, Diesel B, Gruhlke MCH, et al. (2012). Selenium- and tellurium-containing redox modulators with distinct activity against macrophages: possible implications for the treatment of inflammatory diseases. Tetrahedron 68:10577–85
   Web of Science ®Google Scholar
• Du Y, Zhang H, Zhang X, et al. (2013). Thioredoxin 1 is inactivated due to oxidation induced by peroxiredoxin under oxidative stress and reactivated by the glutaredoxin system. J Biol Chem 288:32241–7
   PubMed Web of Science ®Google Scholar
• Duhan NW, Miya TS. (1957). A note on a simple apparatus for detecting neurological deficit in rats and mice. J Am Pharm Assoc 46:208–9
   Google Scholar
• Engman L, Al-Maharik N, McNaughton M, et al. (2003a). Thioredoxin reductase and cancer cell growth inhibition by organotellurium antioxidants. Anticancer Drugs 14:153–61
   PubMed Web of Science ®Google Scholar
• Engman L, Al-Maharik N, McNaughton M, et al. (2003b). Thioredoxin reductase and cancer cell growth inhibition by organotellurium compounds that could be selectively incorporated into tumor cells. Bioorg Med Chem 11:5091–100
   PubMed Web of Science ®Google Scholar
• Engman L, Kanda T, Gallegos A, et al. (2000). Water-soluble organotellurium compounds inhibit thioredoxin reductase and the growth of human cancer cells. Anticancer Drug Des 15:323–30
   PubMedGoogle Scholar
• Farina M, Cereser V, Portela LV, et al. (2005). Methylmercury increases S100B content in rat cerebrospinal fluid. Environ Toxicol Pharmacol 19:249–53
   PubMed Web of Science ®Google Scholar
• Flora SJS, Pande M, Kannan GM, Mehta A. (2004). Lead induced oxidative stress and its recovery following co-administration of melatonin or n-acetylcysteine during chelation with succimer in male rats. Cell Mol Biol 50, on line: OL543–51
   Google Scholar
• Fox WM. (1965). Reflex-ontogeny and behavioural development of the mouse. Anim Behav 13:234–41
   PubMed Web of Science ®Google Scholar
• Frazer AD. (1930). Tellurium in the treatment of syphilis. Lancet 216: 133–4
   Google Scholar
• Funchal C, Carvalho CA, Gemelli T, et al. (2010). Effect of acute administration of 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one on oxidative stress in cerebral cortex, hippocampus, and cerebellum of rats. Cell Mol Neurobiol 30:1135–42
   PubMed Web of Science ®Google Scholar
• Funchal C, de Andrade RB, Turcatel E, et al. (2011). Acute treatment with the organochalcogen 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one produces behavioral changes and inhibition of creatine kinase activity in the brain of rats. Int J Dev Neurosci 29:903–7
   PubMed Web of Science ®Google Scholar
• Hardman R. (2006). A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect 114:165–72
   PubMed Web of Science ®Google Scholar
• Hayun M, Saida H, Albeck M, et al. (2009). Induction therapy in a multiple myeloma mouse model using a combination of AS101 and melphalan, and the activity of AS101 in a tumor microenvironment model. Exp Hematol 37:593–603
   PubMed Web of Science ®Google Scholar
• Heimfarth L, Loureiro SO, Dutra MF, et al. (2012a). In vivo treatment with diphenyl ditelluride induces neurodegeneration in striatum of young rats: implications of MAPK and Akt pathways. Toxicol Appl Pharmacol 264:143–52
   PubMed Web of Science ®Google Scholar
• Heimfarth L, Loureiro SO, Dutra MF, et al. (2013). Disrupted cytoskeletal homeostasis, astrogliosis and apoptotic cell death in the cerebellum of preweaning rats injected with diphenyl ditelluride. Neurotoxicology 34:175–88
   PubMed Web of Science ®Google Scholar
• Heimfarth L, Loureiro SO, Reis KP, et al. (2011). Cross-talk among intracellular signaling pathways mediates the diphenyl ditelluride actions on the hippocampal cytoskeleton of young rats. Chem Res Toxicol 24:1754–64
   PubMed Web of Science ®Google Scholar
• Heimfarth L, Loureiro SO, Reis KP, et al. (2012b). Diphenyl ditelluride induces hypophosphorylation of intermediate filaments through modulation of DARPP-32-dependent pathways in cerebral cortex of young rats. Arch Toxicol 86:217–30
   PubMed Web of Science ®Google Scholar
• Heimfarth L, Loureiro SO, Zamoner A, et al. (2008). Effects of in vivo treatment with diphenyl ditelluride on the phosphorylation of cytoskeletal proteins in cerebral cortex and hippocampus of rats. Neurotoxicology 29:40–7
   PubMed Web of Science ®Google Scholar
• Heimfarth L, Reis KP, Loureiro SO, et al. (2012c). Exposure of young rats to diphenyl ditelluride during lactation affects the homeostasis of the cytoskeleton in neural cells from striatum and cerebellum. Neurotoxicology 33:1106–16
   PubMed Web of Science ®Google Scholar
• Holmgren A. (1968). Thioredoxin. 6. The amino acid sequence of the protein from Escherichia coli B. Eur J Biochem 6:475–84
   PubMedGoogle Scholar
• Holmgren A, Björnstedt M. (1995). Thioredoxin and thioredoxin reductase. Methods Enzymol 252:199–208
   PubMed Web of Science ®Google Scholar
• Holmgren A, Lu J. (2010). Thioredoxin and thioredoxin reductase: current research with special reference to human disease. Biochem Biophys Res Commun 396:120–4
   PubMed Web of Science ®Google Scholar
• Jamier V, Ba LA, Jacob C. (2010). Selenium- and tellurium-containing multifunctional redox agents as biochemical redox modulators with selective cytotoxicity. Chemistry 16:10920–8
   PubMed Web of Science ®Google Scholar
• Klaine SJ, Alvarez PJ, Batley GE, et al. (2008). Nanomaterials in the environment: behavior, fate, bioavailability, and effects. Environ Toxicol Chem 27:1825–51
   PubMed Web of Science ®Google Scholar
• Kudin AP, Augustynek B, Lehmann AK, et al. (2012). The contribution of thioredoxin-2 reductase and glutathione peroxidase to H(2)O(2) detoxification of rat brain mitochondria. Biochim Biophys Acta 1817:1901–6
   PubMed Web of Science ®Google Scholar
• Laden BP, Porter TD. (2001). Inhibition of human squalene monooxigenase by tellurium compounds: evidence of interaction with vicinal sulfhydryls. J Lipid Res 42:235–40
   PubMed Web of Science ®Google Scholar
• Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–75
   PubMed Web of Science ®Google Scholar
• Maciel EN, Bolzan RC, Braga AL, Rocha JB. (2000). Diphenyl diselenide and diphenyl ditelluride differentially affect delta-aminolevulinate dehydratase from liver, kidney, and brain of mice. J Biochem Mol Toxicol 14:310–19
   PubMed Web of Science ®Google Scholar
• McMillan PJ, Patzewitz EM, Young SE, et al. (2009). Differential inhibition of high and low M. Parasitology 136:27–33
   PubMedGoogle Scholar
• McNaughton M, Engman L, Birmingham A, et al. (2004). Cyclodextrin-derived diorganyl tellurides as glutathione peroxidase mimics and inhibitors of thioredoxin reductase and cancer cell growth. J Med Chem 47:233–9
   PubMed Web of Science ®Google Scholar
• Mecklenburg S, Shaaban S, Ba LA, et al. (2009). Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing multifunctional redox agents. Org Biomol Chem 7:4753–62
   PubMed Web of Science ®Google Scholar
• Meinerz DF, Comparsi B, Allebrandt J, et al. (2013). Sub-acute administration of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate induces toxicity and oxidative stress in mice: unexpected effects of N-acetylcysteine. Springerplus 2:182–9
   PubMedGoogle Scholar
• Meotti FC, Borges VC, Zeni JBT, Nogueira CW. (2003). Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and ebselen for rats and mice. Toxicol Lett 143:9–16
   PubMed Web of Science ®Google Scholar
• Moldeus P, Cotgreave IA, Berggren M. (1986). Lung protection by a thiolcontaining antioxidant: N-acetylcysteine. Respiration 50:31–42
   PubMed Web of Science ®Google Scholar
• Moretto MB, Funchal C, Zeni G, et al. (2005a). Selenium compounds prevent the effects of methylmercury on the in vitro phosphorylation of cytoskeletal proteins in cerebral cortex of young rats. Toxicol Sci 85:639–46
   PubMed Web of Science ®Google Scholar
• Moretto MB, Funchal C, Zeni G, et al. (2005b). Organoselenium compounds prevent hyperphosphorylation of cytoskeletal proteins induced by the neurotoxic agent diphenyl ditelluride in cerebral cortex of young rats. Toxicology 210:213–22
   PubMed Web of Science ®Google Scholar
• Nogueira CW, Zeni G, Rocha JBT. (2004). Organoselenium and organo-tellurium compounds: toxicology and pharmacology. Chem Rev 104:6255–85
   PubMed Web of Science ®Google Scholar
• Ogra Y. (2009). Toxicometallomics for research on the toxicology of exotic metalloids based on speciation studies. Anal Sci 25:1189–95
   PubMed Web of Science ®Google Scholar
• Penz J, Gemelli T, Carvalho CA, et al. (2009). Effect of 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one on oxidative stress in cerebral cortex of rats. Food Chem Toxicol 47:745–51
   PubMed Web of Science ®Google Scholar
• Petragnani N. (1994). Preparation of the principal classes of organic tellurium compounds. In: Katritzky AR, Meth-Cohn O, Rees CW, eds. Tellurium in organic synthesis. London: Academic Press
   Google Scholar
• Pinton S, Luchese C, Stangherlin EC, et al. (2010). Diphenyl ditelluride induces neurotoxicity and impairment of developmental behavioral in rat pups. J Braz Chem Soc 21:2130–7
   Web of Science ®Google Scholar
• Prauchner CA, Prestes Ade S, Nogueira CW, Rocha JB. (2013). Effects of diphenyl diselenide and diphenyl ditellurite on chicken embryo development. Toxicol Mech Methods 23:660–4
   PubMed Web of Science ®Google Scholar
• Prescott L. (2005). Oral or intravenous N-acetylcysteine for acetaminophen poisoning? Ann Emerg Med 45:409–13
   PubMed Web of Science ®Google Scholar
• Quines CB, Rosa SG, Neto JS, et al. (2013). Phenylethynyl-butyltellurium inhibits the sulfhydryl enzyme Na+, K+-ATPase: an effect dependent on the tellurium atom. Biol Trace Elem Res 155:261–6
   PubMed Web of Science ®Google Scholar
• Rocha JB, Saraiva RA, Garcia SC, et al. (2012). Aminolevulinate dehydratase (ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations. Toxicology Res 1:85–102
   Web of Science ®Google Scholar
• Salerno Pimentel IA, Paladi Cde S, Katz S, et al. (2012). In vitro and in vivo activity of an organic tellurium compound on Leishmania (Leishmania) chagasi. PLoS One 7:e48780
   Web of Science ®Google Scholar
• Sathish P, Paramasivan V, Palani V, Sivanesan K. (2011). N-Acetylcysteine attenuates dimethylnitrosamine induced oxidative stress in rats. Eur J Pharmacol 654:181–6
   Google Scholar
• Souza AC, Stangherlin EC, Ardais AP, Nogueira CW. (2010). Diphenyl diselenide and diphenyl ditelluride: neurotoxic effect in brain of young rats, in vitro. Mol Cell Biochem 340:179–85
   PubMed Web of Science ®Google Scholar
• Stangherlin EC, Favero AM, Zeni G, et al. (2005). Teratogenic vulnerability of Wistar rats to diphenyl ditelluride. Toxicology 2:231–9
   Google Scholar
• Stangherlin EC, Rocha JBT, Nogueira CW. (2009). Diphenyl ditelluride impairs short term memory and alters neurochemical parameters in young rats. Pharmacol Biochem Behav 91:430–5
   PubMed Web of Science ®Google Scholar
• Wendel A. (1981). Glutathione peroxidase. Methods Enzymol 77:325–33
   PubMedGoogle Scholar