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Research Article

Protective effects of escin against indomethacin-induced gastric ulcer in mice

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Pages 560-566 | Received 14 Jun 2014, Accepted 27 Jul 2014, Published online: 19 Aug 2014

References

  • Abbas AM, Sakr HF. (2013). Effect of selenium and grape seed extract on indomethacin-induced gastric ulcers in rats. J Physiol Biochem 69:527–37
  • Abdallah DM. (2010). Nicotinamide alleviates indomethacin-induced gastric ulcers: a novel antiulcer agent. Eur J Pharmacol 627:276–80
  • Aebi H. (1984). Catalase in vitro. Methods Enzymol 105:121–6
  • Appleyard CB, McCafferty DM, Tigley AW, et al. (1996). Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence. Am J Physiol 270:G42–8
  • Bradley PP, Priebat DA, Christensen RD, Rothstein G. (1982). Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78:206–9
  • Chandrasekharan UM, Siemionow M, Unsal M. (2007). Tumor necrosis factor alpha (TNF-alpha) receptor-II is required for TNF-alpha-induced leukocyte-endothelial interaction in vivo. Blood 109:1938–44
  • Chatterjee A, Khatua S, Chatterjee S. (2013). Polysaccharide-rich fraction of Termitomyces eurhizus accelerate healing of indomethacin induced gastric ulcer in mice. Glycoconj J 30:759–68
  • De Souza GE, Cardoso RA, Melo MC. (2002). A comparative study of the antipyretic effects of indomethacin and dipyrone in rats. Inflamm Res 51:24–32
  • Dokmeci D, Akpolat M, Aydogdu N, et al. (2005). l-carnitine inhibits ethanol-induced gastric mucosal injury in rats. Pharmacol Rep 57:481–8
  • El-Abhar HS. (2010). Coenzyme Q10: a novel gastroprotective effect via modulation of vascular permeability, prostaglandin E(2), nitric oxide and redox status in indomethacin-induced gastric ulcer model. Eur J Pharmacol 649:314–9
  • Evans TJ, Buttery LD, Carpenter A, et al. (1996). Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria. Proc Natl Acad Sci USA 93:9553–8
  • Fu F, Hou Y, Jiang W, et al. (2005). Escin: inhibiting inflammation and promoting gastrointestinal transit to attenuate formation of postoperative adhesions. World J Surg 29:1614–20; discussion:1621–2
  • Guillaume M, Padioleau F. (1994). Veinotonic effect, vascular protection, anti-inflammatory and free radical scavenging properties of horse chestnut extract. Arzneimittelforschung 44:25–35
  • Halici M, Odabasoglu F, Suleyman H, et al. (2005). Effects of water extract of Usnea longissima on antioxidant enzyme activity and mucosal damage caused by indomethacin in rats. Phytomedicine 12:656–62
  • Hu XM, Zhang Y, Zeng FD. (2004). Effects of sodium beta-aescin on expression of adhesion molecules and migration of neutrophils after middle cerebral artery occlusion in rats. Acta Pharmacol Sin 25:869–75
  • Karakus B, Odabasoglu F, Cakir A. (2009). The effects of methanol extract of Lobaria pulmonaria, a lichen species, on indometacin-induced gastric mucosal damage, oxidative stress and neutrophil infiltration. Phytother Res 23:635–9
  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–75
  • Marhuenda E, Alarcon de la Lastra C, Martin MJ. (1994). Antisecretory and gastroprotective effects of aescine in rats. Gen Pharmacol 25:1213–19
  • Mates JM, Perez-Gomez C, Nunez de Castro I. (1999). Antioxidant enzymes and human diseases. Clin Biochem 32:595–603
  • Matsuda H, Li Y, Yoshikawa M. (1999). Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in rats. Eur J Pharmacol 373:63–70
  • McCord JM, Fridovich I. (1969). Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 244:6049–55
  • Miura T, Muraoka S, Fujimoto Y. (2002). Lipid peroxidation induced by indomethacin with horseradish peroxidase and hydrogen peroxide: involvement of indomethacin radicals. Biochem Pharmacol 63:2069–74
  • Motawi TK, Abd Elgawad HM, Shahin NN. (2008). Gastroprotective effect of leptin in indomethacin-induced gastric injury. J Biomed Sci 15:405–12
  • Nagaya H, Satoh H, Maki Y. (1987). Actions of antisecretory agents on proton transport in hog gastric microsomes. Biochem Pharmacol 36:513–9
  • Naito Y, Yoshikawa T, Yoshida N, Kondo M. (1998). Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury. Dig Dis Sci 43:30S–4S
  • Nishida K, Ohta Y, Kobayashi T, Ishiguro I. (1997). Involvement of the xanthine-xanthine oxidase system and neutrophils in the development of acute gastric mucosal lesions in rats with water immersion restraint stress. Digestion 58:340–51
  • Odabasoglu F, Halici Z, Cakir A. (2008). Beneficial effects of vegetable oils (corn, olive and sunflower oils) and alpha-tocopherol on anti-inflammatory and gastrointestinal profiles of indomethacin in rats. Eur J Pharmacol 591:300–6
  • Ohkawa H, Ohishi N, Yagi K. (1979). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351–8
  • Paglia DE, Valentine WN. (1967). Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70:158–69
  • Panes J, Perry M, Granger DN. (1999). Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention. Br J Pharmacol 126:537–50
  • Santucci L, Fiorucci S, Giansanti M, et al. (1994). Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha. Gut 35:909–15
  • Souza MH, Mota JM, Oliveira RB, Cunha FQ. (2008). Gastric damage induced by different doses of indomethacin in rats is variably affected by inhibiting iNOS or leukocyte infiltration. Inflamm Res 57:28–33
  • Suleyman H, Albayrak A, Bilici M, et al. (2010). Different mechanisms in formation and prevention of indomethacin-induced gastric ulcers. Inflammation 33:224–34
  • Tarnawski AS, Ahluwalia A, Jones MK. (2012). The mechanisms of gastric mucosal injury: focus on microvascular endothelium as a key target. Curr Med Chem 19:4–15
  • Utsumi H, Yasukawa K, Soeda T, et al. (2006). Noninvasive mapping of reactive oxygen species by in vivo electron spin resonance spectroscopy in indomethacin-induced gastric ulcers in rats. J Pharmacol Exp Ther 317:228–35
  • Wallace JL, McKnight W, Miyasaka M. (1993). Role of endothelial adhesion molecules in NSAID-induced gastric mucosal injury. Am J Physiol 265:G993–8
  • Wu W, Chen Y, d’Avignon A, Hazen SL. (1999). 3-Bromotyrosine and 3,5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: potential markers for eosinophil-dependent tissue injury in vivo. Biochemistry 38:3538–48
  • Yadav SK, Adhikary B, Chand S, et al. (2012). Molecular mechanism of indomethacin-induced gastropathy. Free Radic Biol Med 52:1175–87
  • Zapata-Colindres JC, Zepeda-Gomez S, Montano-Loza A, et al. (2006). The association of Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs in peptic ulcer disease. Can J Gastroenterol 20:277–80

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