Cigarette smoke extract-induced BEAS-2B cell apoptosis and anti-oxidative Nrf-2 up-regulation are mediated by ROS-stimulated p38 activation

References

• Asano H, Horinouchi T, Mai Y, et al. (2012). Nicotine- and tar-free cigarette smoke induces cell damage through reactive oxygen species newly generated by PKC-dependent activation of NADPH oxidase. J Pharmacol Sci 118:275–87
   PubMed Web of Science ®Google Scholar
• Baglole CJ, Bushinsky SM, Garcia TM, et al. (2006). Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema. Am J Physiol Lung Cell Mol Physiol 291:L19–29
   PubMed Web of Science ®Google Scholar
• Bodur C, Kutuk O, Karsli-Uzunbas G, et al. (2013). Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling. PLoS One 8:e56369
   Web of Science ®Google Scholar
• Burns DM. (1991). Cigarettes and cigarette smoking. Clin Chest Med 12:631–42
   PubMed Web of Science ®Google Scholar
• Celli BR, MacNee W. (2004). Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 23:932–46
   PubMed Web of Science ®Google Scholar
• Chen Y, Luo H, Kang N, et al. (2012). Beraprost sodium attenuates cigarette smoke extract-induced apoptosis in vascular endothelial cells. Mol Biol Rep 39:10447–57
   PubMed Web of Science ®Google Scholar
• Chen ZH, Kim HP, Sciurba FC, et al. (2008). Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One 3:e3316
   PubMed Web of Science ®Google Scholar
• Chin YT, Liao YW, Fu MM, et al. (2011). Nrf-2 regulatescyclosporine-stimulated HO-1 expression in gingiva. J Dent Res 90:995–1000
   PubMed Web of Science ®Google Scholar
• Cho HY, Jedlicka AE, Reddy SP, et al. (2002). Role of NRF2 in protection against hyperoxic lung injury in mice. Am J Respir Cell Mol Biol 26:175–82
   PubMed Web of Science ®Google Scholar
• Damico R, Simms T, Kim BS, et al. (2011). p53 mediates cigarette smoke-induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factor. Am J Respir Cell Mol Biol 44:323–32
   PubMed Web of Science ®Google Scholar
• Das A, Gopalakrishnan B, Voss OH, et al. (2012). Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling. Biochem Pharmacol 84:486–97
   PubMed Web of Science ®Google Scholar
• Dong X, Li Z, Wang W, et al. (2011). Protective effect of canolol from oxidative stress-induced cell damage in ARPE-19 cells via an ERK mediated antioxidative pathway. Mol Vis 17:2040–8
   PubMed Web of Science ®Google Scholar
• Duque RE, Phan SH, Hudson JL, et al. (1985). Functional defects in phagocytic cells following thermal injury. Application of flow cytometric analysis. Am J Pathol 118:116–27
   PubMed Web of Science ®Google Scholar
• Eom HJ, Choi J. (2009). Oxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, Beas-2B. Toxicol Lett 187:77–83
   PubMed Web of Science ®Google Scholar
• Farrugia G, Balzan R. (2012). Oxidative stress and programmed cell death in yeast. Front Oncol 2:64
   PubMedGoogle Scholar
• Gao N, Rahmani M, Dent P, Grant S. (2005). 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process. Oncogene 24:3797–809
   PubMed Web of Science ®Google Scholar
• Horwath-Winter J, Simon M, Kolli H, et al. (2004). Cytotoxicity evaluation of soft contact lens care solutions on human conjunctival fibroblasts. Ophthalmologica 218:385–9
   PubMed Web of Science ®Google Scholar
• Hu W, Xie J, Zhao J, et al. (2009). Involvement of Bcl-2 family in apoptosis and signal pathways induced by cigarette smoke extract in the human airway smooth muscle cells. DNA Cell Biol 28:13–22
   PubMed Web of Science ®Google Scholar
• Ju SM, Pae HO, Kim WS, et al. (2014). Role of reactive oxygen species in p53 activation during cisplatin-induced apoptosis of rat mesangial cells. Eur Rev Med Pharmacol Sci. 18:1135–41
   PubMed Web of Science ®Google Scholar
• Kojima J, Araya J, Hara H, et al. (2013). Apoptosis inhibitor of macrophage (AIM) expression in alveolar macrophages in COPD. Respir Res 14:30
   PubMed Web of Science ®Google Scholar
• Kosmider B, Messier EM, Chu HW, Mason RJ. (2011). Human alveolar epithelial cell injury induced by cigarette smoke. PLoS One 6:e26059
   PubMed Web of Science ®Google Scholar
• Lau WK, Chan SC, Law AC, et al. (2012). The role of MAPK and Nrf2 pathways in ketanserin-elicited attenuation of cigarette smoke-induced IL-8 production in human bronchial epithelial cells. Toxicol Sci 125:569–77
   PubMed Web of Science ®Google Scholar
• Lee KH, Yoo CG. (2013). Simultaneous inactivation of GSK-3beta suppresses quercetin-induced apoptosis by inhibiting the JNK pathway. Am J Physiol Lung Cell Mol Physiol 304:L782–9
   Web of Science ®Google Scholar
• Leonard MO, Kieran NE, Howell K, et al. (2006). Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury. FASEB J 20:2624–6
   PubMed Web of Science ®Google Scholar
• Li FF, Shen J, Shen HJ, et al. (2012). Shp2 plays an important role in acute cigarette smoke-mediated lung inflammation. J Immunol 189:3159–67
   PubMed Web of Science ®Google Scholar
• Li Q, Suen TC, Sun H, et al. (2009). Nickel compounds induce apoptosis in human bronchial epithelial Beas-2B cells by activation of c-Myc through ERK pathway. Toxicol Appl Pharmacol 235:191–8
   PubMed Web of Science ®Google Scholar
• Liu Y, Min W. (2002). Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. Circ Res 90:1259–66
   PubMed Web of Science ®Google Scholar
• Loo DT, Rillema JR. (1998). Measurement of cell death. Methods Cell Biol 57:251–64
   PubMed Web of Science ®Google Scholar
• Nguyen T, Nioi P, Pickett CB. (2009). The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 284:13291–5
   PubMed Web of Science ®Google Scholar
• Orr WS, Denbo JW, Saab KR, et al. (2013). Curcumin potentiates rhabdomyosarcoma radiosensitivity by suppressing NF-kappaB activity. PLoS One 8:e51309
   PubMed Web of Science ®Google Scholar
• Pan J, Chang Q, Wang X, et al. (2010). Reactive oxygen species-activated Akt/ASK1/p38 signaling pathway in nickel compound-induced apoptosis in BEAS 2B cells. Chem Res Toxicol 23:568–77
   PubMed Web of Science ®Google Scholar
• Park EJ, Yi J, Chung KH, et al. (2008). Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. Toxicol Lett 180:222–9
   PubMed Web of Science ®Google Scholar
• Park JW, Lee MH, Choi JO, et al. (2012). Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid. Exp Mol Med 42:105–15
   Web of Science ®Google Scholar
• Prieto P, Cuenca J, Traves PG, et al. (2010). Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways. Cell Death Differ 17:1179–88
   PubMed Web of Science ®Google Scholar
• Rahman I, van Schadewijk AA, Crowther AJ, et al. (2002). 4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 166:490–5
   PubMed Web of Science ®Google Scholar
• Rangasamy T, Cho CY, Thimmulappa RK, et al. (2004). Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 114:1248–59
   PubMed Web of Science ®Google Scholar
• Saito J, Toriumi S, Awano K, et al. (2007). Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon. Biochem J 405:591–6
   PubMed Web of Science ®Google Scholar
• Schweitzer KS, Hatoum H, Brown MB, et al. (2011). Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides. Am J Physiol Lung Cell Mol Physiol 301:L836–46
   PubMed Web of Science ®Google Scholar
• Teramoto S, Tomita T, Matsui H, et al. (1999). Hydrogen peroxide-induced apoptosis and necrosis in human lung fibroblasts: protective roles of glutathione. Jpn Pharmacol 79:33–40
   PubMedGoogle Scholar
• Tuder RM, Yoshida T, Fijalkowka I, et al. (2006). Role of lung maintenance program in the heterogeneity of lung destruction in emphysema. Proc Am Thorac Soc 3:673–9
   PubMedGoogle Scholar
• Uhal BD, Joshi I, Hughes WF, et al. (1998). Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol 275:L1192–9
   PubMed Web of Science ®Google Scholar
• Vermes I, Haanen C, Reutelingsperger C. (2000). Flow cytometry of apoptotic cell death. J Immunol Methods 243:167–90
   PubMed Web of Science ®Google Scholar
• Wang J, Li N, Zheng L, et al. (2011). P38-Nrf-2 signaling pathway of oxidative stress in mice caused by nanoparticulate TiO2. Biol Trace Elem Res 140:186–97
   PubMed Web of Science ®Google Scholar
• Witherden IR, Vanden Bon EJ, Goldstraw P, et al. (2004). Primary human alveolar type II epithelial cell chemokine release: effects of cigarette smoke and neutrophil elastase. Am J Respir Cell Mol Biol 30:500–9
   PubMed Web of Science ®Google Scholar
• Woo CC, Hsu A, Kumar AP, et al. (2013). Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS. PLoS One 8:e75356
   PubMed Web of Science ®Google Scholar
• Yang YM, Liu GT. (2004). Damaging effect of cigarette smoke extract on primary cultured human umbilical vein endothelial cells and its mechanism. Biomed Environ Sci 17:121–34
   PubMed Web of Science ®Google Scholar
• Yoon DH, Lim MH, Lee YR, et al. (2013). A novel synthetic analog of militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells. Toxicol Appl Pharmacol 273:659–71
   PubMed Web of Science ®Google Scholar
• Zhang LH, Jia YL, Lin XX, et al. (2013). AD-1, a novel ginsenoside derivative, shows anti-lung cancer activity via activation of p38 MAPK pathway and generation of reactive oxygen species. Biochim Biophys Acta 1830:4148–59
   PubMed Web of Science ®Google Scholar