Possible mechanism of PNS protection against cisplatin-induced nephrotoxicity in rat models

References

• Brahimi-Horn MC, Pouyssegur J. (2009). Highlights of the European Association of Cancer Research (EACR 2008). Bull Cancer 96:485–99
   PubMedGoogle Scholar
• Bruick RK. (2000). Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 97:9082–7
   PubMed Web of Science ®Google Scholar
• Domitrovic R, Cvijanovic O, Pernjak-Pugel E, et al. (2013). Berberine exerts nephroprotective effect against cisplatin-induced kidney damage through inhibition of oxidative/nitrosative stress, inflammation, autophagy and apoptosis. Food Chem Toxicol 62:397–406
   PubMed Web of Science ®Google Scholar
• El-Ghiaty MA, Ibrahim OM, Abdou SM, Hussein FZ. (2014). Evaluation of the protective effect of cystone against cisplatin-induced nephrotoxicity in cancer patients, and its influence on cisplatinantitumor activity. Int Urol Nephrol 46:1367–73
   PubMed Web of Science ®Google Scholar
• Funderburk SF, Wang QJ, Yue Z. (2010). The Beclin 1-VPS34 complex – at the crossroads of autophagy and beyond. Trends Cell Biol 20:355–62
   PubMed Web of Science ®Google Scholar
• Greijer AE, van der Groep P, Kemming D, et al. (2005). Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). J Pathol 206:291–304
   PubMed Web of Science ®Google Scholar
• Hamacher-Brady A, Brady NR, Logue SE, et al. (2007). Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ 14:146–57
   PubMed Web of Science ®Google Scholar
• Herzog C, Yang C, Holmes A, Kaushal GP. (2012). zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function. Am J Physiol Renal Physiol 303:F1239–50
   PubMed Web of Science ®Google Scholar
• Ishihara M, Urushido M, Hamada K, et al. (2013). Sestrin-2 and BNIP3 regulate autophagy and mitophagy in renal tubular cells in acute kidney injury. Am J Physiol Renal Physiol 305:F495–509
   PubMed Web of Science ®Google Scholar
• Jablonski P, Howden BO, Rae DA, et al. (1983). An experimental model for assessment of renal recovery from warm ischemia. Transplantation 35:198–204
   PubMed Web of Science ®Google Scholar
• Kang R, Zeh HJ, Lotze MT, Tang D. (2011). The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18:571–80
   PubMed Web of Science ®Google Scholar
• Kanki T, Klionsky DJ, Okamoto K. (2011). Mitochondria autophagy in yeast. Antioxid Redox Signal 14:1989–2001
   PubMed Web of Science ®Google Scholar
• Kaushal GP, Kaushal V, Herzog C, Yang C. (2008). Autophagy delays apoptosis in renal tubular epithelial cells in cisplatin cytotoxicity. Autophagy 4:710–12
   PubMed Web of Science ®Google Scholar
• Kim JW, Tchernyshyov I, Semenza GL, Dang CV. (2006). HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 3:177–85
   PubMed Web of Science ®Google Scholar
• Kodama A, Watanabe H, Tanaka R, et al. (2014). Albumin fusion renders thioredoxin an effective anti-oxidative and anti-inflammatory agent for preventing cisplatin-induced nephrotoxicity. Biochim Biophys Acta 1840:1152–62
   PubMed Web of Science ®Google Scholar
• Li J, Xu Z, Jiang L, et al. (2014). Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury. Kidney Int 86:86–102
   PubMed Web of Science ®Google Scholar
• Lira VA, Okutsu M, Zhang M, et al. (2013). Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance. FASEB J 27:4184–93
   PubMed Web of Science ®Google Scholar
• Liu SJ, Zhou SW. (2000). Panax notoginseng saponins attenuated cisplatin-induced nephrotoxicity. Acta Pharmacol Sin 21:257–60
   PubMed Web of Science ®Google Scholar
• Liu WJ, Tang HT, Jia YT, et al. (2010a). Notoginsenoside R1 attenuates renal ischemia-reperfusion injury in rats. Shock 34:314–20
   PubMed Web of Science ®Google Scholar
• Liu Y, Zhang HG, Jia Y, Li XH. (2010b). Panax notoginseng saponins attenuate atherogenesis accelerated by zymosan in rabbits. Biol Pharm Bull 33:1324–30
   PubMed Web of Science ®Google Scholar
• Maiuri MC, Le Toumelin G, Criollo A, et al. (2007). Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 26:2527–39
   PubMed Web of Science ®Google Scholar
• Melillo G. (2004). HIF-1: a target for cancer, ischemia and inflammation – too good to be true? Cell Cycle 3:154–5
   PubMed Web of Science ®Google Scholar
• Ohsumi Y. (2001). Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2:211–16
   PubMed Web of Science ®Google Scholar
• Park MS, De Leon M, Devarajan P. (2002). Cisplatin induces apoptosis in LLC-PK1 cells via activation of mitochondrial pathways. J Am Soc Nephrol 13:858–65
   PubMed Web of Science ®Google Scholar
• Rong L, Chen Y, He M, Zhou X. (2009). Panax notoginseng saponins attenuate acute lung injury induced by intestinal ischaemia/reperfusion in rats. Respirology 14:890–8
   PubMed Web of Science ®Google Scholar
• Rovetta F, Stacchiotti A, Consiglio A, et al. (2012). ER signaling regulation drives the switch between autophagy and apoptosis in NRK-52E cells exposed to cisplatin. Exp Cell Res 318:238–50
   PubMed Web of Science ®Google Scholar
• Schwerdt G, Freudinger R, Schuster C, et al. (2003). Inhibition of mitochondria prevents cell death in kidney epithelial cells by intra- and extracellular acidification. Kidney Int 63:1725–35
   PubMed Web of Science ®Google Scholar
• Wang J, Biju MP, Wang MH, et al. (2006). Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: involvement of mitochondrial inhibition and p53 suppression. J Am Soc Nephrol 17:1875–85
   PubMed Web of Science ®Google Scholar
• Weidberg H, Shvets E, Elazar Z. (2011). Biogenesis and cargo selectivity of autophagosomes. Annu Rev Biochem 80:125–56
   PubMed Web of Science ®Google Scholar
• Yang C, Kaushal V, Shah SV, Kaushal GP. (2008). Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. Am J Physiol Renal Physiol 294:F777–87
   PubMed Web of Science ®Google Scholar
• Yang Z, Schumaker LM, Egorin MJ, et al. (2006). Cisplatin preferentially binds mitochondrial DNA and voltage-dependent anion channel protein in the mitochondrial membrane of head and neck squamous cell carcinoma: possible role in apoptosis. Clin Cancer Res 12:5817–25
   PubMed Web of Science ®Google Scholar
• Yu ML, Zhang CL, Yuan DD, et al. (2012). Panax notoginseng saponins enhances the cytotoxicity of cisplatin via increasing gap junction intercellular communication. Biol Pharm Bull 35:1230–7
   PubMed Web of Science ®Google Scholar
• Zhang C, Tong X, Qi B, et al. (2013). Components of Panax notoginseng saponins enhance the cytotoxicity of cisplatin via their effects on gap junctions. Mol Med Rep 8:897–902
   Web of Science ®Google Scholar
• Zhang H, Bosch-Marce M, Shimoda LA, et al. (2008). Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283:10892–903
   PubMed Web of Science ®Google Scholar
• Zhang H, Gao P, Fukuda R, et al. (2007). HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 11:407–20
   PubMed Web of Science ®Google Scholar
• Zuo W, Zhang S, Xia CY, et al. (2014). Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage. Neuropharmacology 86:103–15
   PubMed Web of Science ®Google Scholar