188
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Non-occlusive topical exposure of human skin in vitro as model for cytotoxicity testing of irritant compounds

, &
Pages 82-87 | Received 29 Jul 2015, Accepted 03 Sep 2015, Published online: 08 Oct 2015

References

  • Ale IS, Maibach HI. (2014). Irritant contact dermatitis. Rev Environ Health 29:195–206
  • Chew A-L, Maibach Howard I. (2006). Irritant dermatitis. 1st ed. Berlin, Heidelberg: Springer-Verlag
  • Draize JH, Alvarez E, Whitesell MF. (1946). Toxicity and primary irritation of some chemical compounds following oral administration and skin application. Fed Proc 5:174
  • Forster M, Bolzinger MA, Fessi H, Briancon S. (2009). Topical delivery of cosmetics and drugs. Molecular aspects of percutaneous absorption and delivery. Eur J Dermatol 19:309–23
  • Honari G, Maibach Howard I. (2014). Applied dermatotoxicology: clinical aspects. 1st ed. Amsterdam: Elsevier
  • Kratz G. (1998). Modeling of wound healing processes in human skin using tissue culture. Microsc Res Tech 42:345–50
  • McNamee PM, Api AM, Basketter DA, et al. (2008). A review of critical factors in the conduct and interpretation of the human repeat insult patch test. Regul Toxicol Pharmacol 52:24–34
  • Mosmann T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55–63
  • Netzlaff F, Lehr CM, Wertz PW, Schaefer UF. (2005). The human epidermis models EpiSkin, SkinEthic and EpiDerm: an evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport. Eur J Pharm Biopharm 60:167–78
  • Ngo MA, Maibach HI. (2010). Dermatotoxicology: historical perspective and advances. Toxicol Appl Pharmacol 243:225–38
  • Ponec M. (1992). In vitro cultured human skin cells as alternatives to animals for skin irritancy screening. Int J Cosmet Sci 14:245–64
  • Robinson MK, Perkins MA, Basketter DA. (1998). Application of a 4-h human patch test method for comparative and investigative assessment of skin irritation. Contact Dermatitis 38:194–202
  • Welss T, Basketter DA, Schroder KR. (2004). In vitro skin irritation: facts and future. State of the art review of mechanisms and models. Toxicol In Vitro 18:231–43
  • Wilhelm Klaus Peter ZH, Maibach Howard I. (2012). Dermatotoxicology. 8th ed. Boca Raton (FL): Informa Healthcare

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.