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Research Article

Simultaneous Quantitation of Allyl Alcohol, Ethanol, and Their Metabolites in the Blood by Head-Space Gas Chromatography

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Pages 153-159 | Received 04 Mar 1995, Accepted 30 Jun 1995, Published online: 27 Sep 2008

References

  • Butterworth K R, Carpanini F MB, Dunnington D. The production of periportal necrosis by allyl alcohol in the rat. Br J Pharmacol 1978; 63: 353–354
  • Patel J M, Wood J C, Leibman K C. The biotransformation of allyl alcohol and acrolein in rat liver and lung preparations. Drug Metab Dispos 1980; 8: 305–308
  • Belinsky S A, Bradford B U, Forman D T, Glassman E B, Felder M R, Thurman R G. Hepatotoxicity due to allyl alcohol in deermice depends on alcohol dehydrogenase. Hepatology 1985; 5: 1179–1182
  • Ohno Y, Ormstad K, Ross D, Orrenius S. Mechanism of allyl alcohol toxicity and protective effects of low‐molecular‐weight thiols studied with isolated rat hepatocytes. Toxicol Appl Pharmacol 1985; 78: 169–179
  • Mitchell D Y, Peterson D R. Metabolism of the glutathione‐acrolein adduct, S‐(2‐aldehydoethyl)glutathione, by rat liver alcohol and aldehyde dehydrogenase. J Pharmacol Exp Ther 1989; 251: 193–198
  • Lieber C S. Pathways of ethanol metabolism and related pathology. Alcoholism: A molecular perspective, T N Palmer. Plenum, New York 1991; 1–13
  • Burbridge T N, Hine C N, Schick A F. Simple spectrophotometric method for the determination of acetaldehyde in blood. J Lab Clin Med 1950; 35: 985–987
  • Ellis F W, Hill J B. Automated fluorometric procedure for the enzymic determination of ethanol in fingertip blood. Clin Chem 1969; 15: 91–101
  • Eriksson C JP, Sippel H W, Forsander O A. The determination of acetaldehyde in biological samples by head‐space gas chromatography. Anal Biochem 1977; 80: 116–124
  • Lundquist F. Determination of ethyl alcohol in blood and tissues. Methods Biochem Anal 1959; 7: 217–251
  • Mendenhall C L, MacGee J, Green E S. Simple rapid and sensitive method for the simultaneous quantitation of ethanol and acetaldehyde in biological materials using head‐space gas chromatography. J Chromatogr 1980; 190: 197–200
  • Nagy J L, Leisztner L, Veghelyi P V. Acetaldehyde: its “disappearance” from human blood. Anal Biochem 1985; 151: 365–368
  • Adams J D, Klaidman L K. Acrolein‐induced oxygen radical formation. Free Rad Biol Med 1993; 15: 187–193
  • Cohen I R, Altshuller A P. A new spectrophotometric method for the determination of acrolein in combustion gases and in the atmosphere. Anal Chem 1961; 33: 726–733
  • Lam C W, Casanova M, Heck H. Depletion of nasal mucosal glutathione by acrolein and enhancement of formaldehyde‐induced DNA‐protein cross‐linking by simultaneous exposure to acrolein. Arch Toxicol 1985; 58: 67–71

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