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ORIGINAL RESEARCH

p38 Mitogen-activated Protein Kinase is Not Activated in the Quadriceps of Patients with Stable Chronic Obstructive Pulmonary Disease

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Pages 142-150 | Published online: 12 Mar 2012

References

  • Seymour JM, Spruit MA, Hopkinson NS, The prevalence of quadriceps weakness in COPD and the relationship with disease severity. Eur Respir J 2010; 36(1):81–88.
  • Marquis K, Debigare R, Lacasse Y, Midthigh muscle cross-sectional area is a better predictor of mortality than body mass index in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002; 166(6):809–813.
  • Swallow EB, Reyes D, Hopkinson NS, Quadriceps strength predicts mortality in patients with moderate to severe chronic obstructive pulmonary disease. Thorax 2007; 62(2):115–120.
  • Liu W, Liang Q, Balzar S, Cell-specific activation profile of extracellular signal-regulated kinase 1/2, Jun N-terminal kinase, and p38 mitogen-activated protein kinases in asthmatic airways. J Allergy Clin Immunol 2008; 121(4):893–902 e2.
  • Renda T, Baraldo S, Pelaia G, Increased activation of p38 MAPK in COPD. Eur Respir J 2008; 31(1):62–69
  • Liu Q, Xu WG, Luo Y, Cigarette smoke-induced skeletal muscle atrophy is associated with up-regulation of USP-19 via p38 and ERK MAPKs. J Cell Biochem 2011; in press.
  • Pitta F, Troosters T, Spruit MA, Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2005; 171(9):972–977.
  • Watz H, Waschki B, Meyer T, Physical activity in patients with COPD. Eur Respir J 2009; 33(2):262–272.
  • Choi I, Lee K, Kim M, Differential activation of stress-responsive signalling proteins associated with altered loading in a rat skeletal muscle. J Cell Biochem 2005; 96(6):1231–1243.
  • Childs TE, Spangenburg EE, Vyas DR, Temporal alterations in protein signaling cascades during recovery from muscle atrophy. Am J Physiol Cell Physiol 2003; 285(2):C391–98.
  • Morris RT, Spangenburg EE, Booth FW. Responsiveness of cell signaling pathways during the failed 15-day regrowth of aged skeletal muscle. J Appl Physiol 2004; 96(1):398–404.
  • Machida S, Booth FW. Changes in signalling molecule levels in 10-day hindlimb immobilized rat muscles. Acta Physiol Scand 2005; 183(2):171–179.
  • Li YP, Chen Y, John J, TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle. FASEB J 2005; 19(3):362–370.
  • Obata T, Brown GE, Yaffe MB. MAP kinase pathways activated by stress: the p38 MAPK pathway. Crit Care Med 2000; 28(4 Suppl):N67–77.
  • Barreiro E, Gea J, Corominas JM, Nitric oxide synthases and protein oxidation in the quadriceps femoris of patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2003; 29(6):771–778.
  • Barreiro E, Schols AM, Polkey MI, Cytokine profile in quadriceps muscles of patients with severe COPD. Thorax 2008; 63(2):100–107.
  • Powers SK, Kavazis AN, McClung JM. Oxidative stress and disuse muscle atrophy. J Appl Physiol 2007; 102(6):2389–2397.
  • Lemire BB, Debigaré R, Theriault M, MAPK Signaling In The quadriceps of patients with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2011; 183:A2527.
  • Kent LM, Smyth LJ, Plumb J, Inhibition of lipopolysaccharide-stimulated chronic obstructive pulmonary disease macrophage inflammatory gene expression by dexamethasone and the p38 mitogen-activated protein kinase inhibitor N-cyano-N’-(2-{[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7-oxo-7,8-dihydropyrido[2,3-d] pyrimidin-2-yl]amino}ethyl)guanidine (SB706504). J Pharmacol Exp Ther 2009; 328(2):458–468.
  • Montalban AG, Boman E, Chang CD, KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase. Eur J Pharmacol 2010; 632(1–3):93–102.
  • Singh D, Smyth L, Borrill Z, A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol 2010; 50(1):94–100.
  • Medicherla S, Fitzgerald MF, Spicer D, p38alpha-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation. J Pharmacol Exp Ther 2008; 324(3):921–929.
  • Rabe KF, Hurd S, Anzueto A, Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007; 176(6):532–555.
  • Steiner MC, Barton RL, Singh SJ, Bedside methods versus dual energy X-ray absorptiometry for body composition measurement in COPD. Eur Respir J 2002; 19(4):626–631.
  • Edwards RHT, Young A, Hosking GP, Human skeletal muscle function: description of tests and normal values. Clin Sci 1977; 52:283–290.
  • Polkey MI, Kyroussis D, Hamnegard C-H, Quadriceps strength and fatigue assessed by magnetic stimulation of the femoral nerve in man. Muscle Nerve 1996; 19:549–555.
  • Bergstrom L. Muscle electrolytes in man. Determination by neutron activation analysis on needle biopsy specimens. A study on normal subjects, kidney patients, and patients with chronic diarrhea. Scand J Clin Lab Invest 1962; 68:1–110.
  • Franssen FM, Broekhuizen R, Janssen PP, Limb muscle dysfunction in COPD: effects of muscle wasting and exercise training. Med Sci Sports Exerc 2005; 37(1):2–9.
  • Cote CG, Casanova C, Marin JM, Validation and comparison of reference equations for the 6-min walk distance test. Eur Respir J 2008; 31(3):571–578.
  • Spruit MA, Polkey MI, Celli B, Predicting Outcomes from 6-Minute Walk Distance in Chronic Obstructive Pulmonary Disease. J Amer Med Direct Asso 2011; in press.
  • Chen S, Qiong Y, Gardner DG. A role for p38 mitogen-activated protein kinase and c-myc in endothelin-dependent rat aortic smooth muscle cell proliferation. Hypertension 2006; 47(2):252–258.
  • Weiss C, Faust D, Durk H, TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway. Oncogene 2005; 24(31):4975–4983.
  • Marinissen MJ, Chiariello M, Gutkind JS. Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway. Genes Dev 2001; 15(5):535–553.
  • Sarkar D, Su ZZ, Lebedeva IV, mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc Natl Acad Sci USA 2002; 99(15):10054–10059.
  • Di Giovanni S, Molon A, Broccolini A, Constitutive activation of MAPK cascade in acute quadriplegic myopathy. Ann Neurol 2004; 55(2):195–206.
  • Swallow EB, Barreiro E, Gosker H, Quadriceps muscle strength in scoliosis. Eur Respir J 2009; 34(6):1429–1435.
  • Wretman C, Widegren U, Lionikas A, Differential activation of mitogen-activated protein kinase signalling pathways by isometric contractions in isolated slow- and fast-twitch rat skeletal muscle. Acta Physiol Scand 2000; 170(1):45–49.
  • Mylabathula DB, Rice KM, Wang Z, Age-associated changes in MAPK activation in fast- and slow-twitch skeletal muscle of the F344/NNiaHSD X Brown Norway/BiNia rat model. Exp Gerontol 2006; 41(2):205–214.
  • Gosker H, Zeegers M, Wouters E, Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis. Thorax 2007; 62(11):944–9.
  • Adachi T, Kikuchi N, Yasuda K, Fibre type distribution and gene expression levels of both succinate dehydrogenase and peroxisome proliferator-activated receptor-gamma coactivator-1alpha of fibres in the soleus muscle of Zucker diabetic fatty rats. Exp Physiol 2007; 92(2):449–455.
  • Gosselink JV, Hayashi S, Elliott WM, Differential expression of tissue repair genes in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010; 181(12):1329–1335.
  • Hamnegard CH, Sedler M, Polkey MI, Quadriceps strength assessed by magnetic stimulation of the femoral nerve in normal subjects. Clin Physiol Funct Imag 2004; 24(5):276–280.
  • Csukly KJ, Martineau LC, Gardiner PF. Inter- and intra-muscle comparisons of MAPK mechanosensitivity: evidence for the absence of fibre-type dependency. Pflugers Arch 2002; 444(6):732–737.
  • Jiang F, Li P, Fornace AJ, Jr., et al. G2/M arrest by 1,25-dihydroxyvitamin D3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer. J Biol Chem 2003; 278(48):48030–48040.
  • Buitrago CG, Ronda AC, de Boland AR, MAP kinases p38 and JNK are activated by the steroid hormone 1alpha,25(OH)2-vitamin D3 in the C2C12 muscle cell line. J Cell Biochem 2006; 97(4):698–708.
  • Janssens W, Bouillon R, Claes B, Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax 2010; 65(3):215–220.
  • Hopkinson NS, Li KW, Kehoe A, Vitamin D receptor genotypes influence quadriceps strength in chronic obstructive pulmonary disease. Am J Clin Nutr 2008; 87(2):385–390.
  • Spruit MA, Gosselink R, Troosters T, Muscle force during an acute exacerbation in hospitalised patients with COPD and its relationship with CXCL8 and IGF-I. Thorax 2003; 58(9):752–756.
  • Pitta F, Troosters T, Probst VS, Physical activity and hospitalization for exacerbation of COPD. Chest 2006; 129(3):536–544.
  • Austin RL, Rune A, Bouzakri K, siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle. Diabetes 2008; 57(8):2066–2073.
  • Crul T, Spruit MA, Gayan-Ramirez G, Markers of inflammation and disuse in vastus lateralis of chronic obstructive pulmonary disease patients. Eur J Clin Invest 2007; 37(11):897–904.
  • Seymour JM, Ward K, Sidhu P, Ultrasound measurement of rectus femoris cross-sectional area and the relationship to quadriceps strength in chronic obstructive pulmonary disease. Thorax 2009; 64:418–423.
  • Doucet M, Russell AP, Leger B, Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007; 176(3):261–269.

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