Montelukast versus Dexamethasone Treatment in a Guinea Pig Model of Chronic Pulmonary Neutrophilic Inflammation

References

• Barnes PJ, Adcock IM. Glucocorticoid resistance in inflammatory diseases. Lancet 2009; 373:1905–1917.
   PubMed Web of Science ®Google Scholar
• Wang W, Li JJ, Foster PS, et al. Potential therapeutic targets for steroid-resistant asthma. Curr Drug Targets 2010; 11(8):957–970.
   PubMed Web of Science ®Google Scholar
• Milara J, Navarro A, Almudéver P, et al. Oxidative stress-induced glucocorticoid resistance is prevented by dual PDE3/PDE4 inhibition in human alveolar macrophages. Clin Exp Allergy 2011; 41(4):535–546.
   PubMed Web of Science ®Google Scholar
• Barnes PJ. Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease. Proc Am Thoracic Soc 2009; 6:693–696.
   PubMedGoogle Scholar
• Montuschi P, Peters-Golden ML. Leukotriene modifiers for asthma treatment. Clin Exp Allergy 2010; 40(12):1732–1741.
   PubMed Web of Science ®Google Scholar
• Montuschi P, Santini G, Valente S, et al. Liquid chromatography-mass spectrometry measurement of leukotrienes in asthma and other respiratory diseases. J Chromatogr B Analyt Technol Biomed Life Sci. 2014; 964(1):12–25.
   PubMed Web of Science ®Google Scholar
• Thompson AB, Daughton D, Robbins RA, et al. Intraluminal airway inflammation in chronic bronchitis—characterization and correlation with clinical parameters. Am Rev Respir Dis 1989; 140:1527–1537.
   PubMed Web of Science ®Google Scholar
• Claesson HE, Odlander B, Jakobsson PJ. 1992. Leukotriene-B4 in the immune-system. Int J Immunopharmacol 14:441–449.
   PubMed Web of Science ®Google Scholar
• Chaney MO, Froelich LL, Gapinski DM, Mallett BE, Jackson WT. Characterization of the spatial arrangement of the 2 acid-binding sites on the human neutrophil ltb (4) receptor. Receptor 1992; 2:169–179.
   PubMedGoogle Scholar
• Conklyn MJ, AlpertRB, Wright KF, Showell HJ. Inhibition of spontaneous apoptosis in neutrophils by 5-lipoxygenase metabolites of arachidonic acid: potential involvement of the low affinity LTB4 receptor. J Leukoc Biol 1997; 55:13.
   Google Scholar
• Montuschi P. Leukotrienes, antileukotrienes and asthma. Mini Rev Med Chem 2008; 8(7):647–656.
   PubMed Web of Science ®Google Scholar
• Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008; 31,143–178.
   PubMed Web of Science ®Google Scholar
• Tintinger GR, Feldman C, Theron AJ. 2010. Montelukast: more than a cysteinyl leukotriene receptor antagonist? Review. Scient World J 2010; 14;10:2403–2413.
   Web of Science ®Google Scholar
• Tsuchida H, Takahashi S, Nosaka E, et al. Novel triple neurokinin receptor antagonist CS-003 inhibits respiratory disease models in guinea pigs. Eur J Pharmacol 2008; 596(1–3):153–159.
   PubMed Web of Science ®Google Scholar
• Wu Y, Zhou C, Tao J, Li S. Montelukast prevents the decrease of interleukin-10 and inhibits NF-kappaB activation in inflammatory airway of asthmatic guinea pigs. Can J Physiol Pharmacol 2006; 84(5):531–537.
   PubMed Web of Science ®Google Scholar
• Toward TJ, Broadler KJ. Chronic lipopolysaccharide exposure on airway function, cell infiltration, and nitric oxide generation in conscious guinea pigs: effect of rolipram and dexamethasone. J Pharmacol Exp Ther 2001; 298:298–306.
   PubMed Web of Science ®Google Scholar
• Kaneko Y, Takashima K, Suzuki N, Yamana K. Effects of theophylline on chronic inflammatory lung injury induced by LPS exposure in guinea pigs. Allergol Int 2007; 56(4):445–456.
   PubMedGoogle Scholar
• Pennock BE, Cox CP, Rogers RM, et al. A non-invasive technique for measurement of changes in specific airway resistance. J Appl Physiol 1979; 46:399–406.
   PubMed Web of Science ®Google Scholar
• Tulić MK, Wale JL, Holt PG, Sly PD. Modification of the inflammatory response to allergen challenge after exposure to bacterial lipopolysaccharide. Am J Respir Cell Mol Biol 2000; 22(5):604–612.
   PubMed Web of Science ®Google Scholar
• Kasahara DI, Perini A, Lopes FD, et al. Effect of salbutamol on pulmonary responsiveness in chronic pulmonary allergic inflammation in guinea pigs. Braz J Med Biol Res 2005; 38(5):723–730.
   PubMed Web of Science ®Google Scholar
• Underwood DC, Osborn RR, Bochnowicz, S, et al. SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. Am J Physiol Lung Cell Mol Physiol 2000; 279(5):L895–902.
   PubMed Web of Science ®Google Scholar
• Buege JA, Aust SD. Microsomal lipid peroxidation. Meth ­Enzymol 1978; 52:302–310.
   PubMedGoogle Scholar
• Wegener D, Wirsching F, Riester D, Schwienhorst A. 2003. A fluorogenic histone deacetylase assay well suited for high-throughput activity screening. Chem. Biol 2003; 10:61–68.
   PubMed Web of Science ®Google Scholar
• Lefort J, Singer M, Leduc D, et al. Systemic administration of endotoxin induces bronchopulmonary hyperreactivity dissociated from TNF-alpha formation and neutrophil sequestration into the murine lungs. J Immunol 1998; 161(1):474–480.
   PubMed Web of Science ®Google Scholar
• Pauwels RA, Kips JC, Peleman RA, Van Der Straeten ME. The effect of endotoxin inhalation on airway responsiveness and cellular influx in rats. Am Rev Respir Dis 1990; 141(3):540–545.
   PubMed Web of Science ®Google Scholar
• Whelan CJ. Inhibition of PAF-, LPS-, and cytokine-induced granulocyte accumulation in guinea pig lung by dexamethasone: evidence that inhibition of IL-5 release is responsible for the selective inhibition of eosinophilia by glucocorticoids in guinea pigs. Inflamm Res 1996; 45: 166–170.
   PubMed Web of Science ®Google Scholar
• Belvisi MG. Regulation of inflammatory cell function by corticosteroids. Proc Am Thorac Soc 2004; 1(3):207–214.
   PubMedGoogle Scholar
• Whelan CJ, Hughes SC, Wren GP. Inhibition of some aspects of acute inflammation of guinea-pig lung by intraperitoneal dexamethasone and mifepristone: demonstration of agonist activity of mifepristone in the guinea-pig. Inflamm Res 1995; 44(3):131–138.
   PubMed Web of Science ®Google Scholar
• Montuschi P, Barnes PJ. New perspectives in pharmacological treatment of mild persistent asthma. Drug Discov Today 2011; 16(23–24):1084–1091.
   PubMed Web of Science ®Google Scholar
• Montuschi P, Malerba M, Santini G, Miravitlles M. Pharmacological treatment of chronic obstructive pulmonary disease: from ­evidence-based medicine to phenotyping. Drug Discov Today 2014; 19(12):1928–1935.
   PubMed Web of Science ®Google Scholar
• Zhu J, Qiu YS, Figueroa DJ, et al. Localization and upregulation of cysteinyl leukotriene-1 receptor in asthmatic bronchial mucosa. Am J Respir Cell Mol Biol 2005; 33(6):531–540.
   PubMed Web of Science ®Google Scholar
• Anderson R, Theron AJ, Gravett CM, et al. Montelukast inhibits neutrophil pro-inflammatory activity by a cyclic AMP-­dependent mechanism. Br J Pharmacol 2009; 156, 105–115.
   PubMed Web of Science ®Google Scholar
• Keatings VM, Collins PD, Scott DM, Barnes PJ. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996; 153(2):530–534.
   PubMed Web of Science ®Google Scholar
• Basyigit I, Sahin M, Sahin D, et al. Anti-inflammatory effects of Montelukast on smoke-induced lung injury in rats. Multidiscip Respir Med 2010; 5(2):92–98.
   PubMed Web of Science ®Google Scholar
• Maeba S, Ichiyama T, Ueno Y, et al. Effect of Montelukast on nuclear factor kappa B activation and proinflammatory molecules. Ann Allergy Asthma Immunol 2005; 94(6):670–674.
   PubMed Web of Science ®Google Scholar
• Can M, Yüksel B, Demirtaş S, Tomaç N. 2006. The effect of Montelukast on soluble interleukin-2 receptor and tumor necrosis factor alpha in pediatric asthma. Allergy Asthma Proc 27(4):383–386.
   PubMed Web of Science ®Google Scholar
• Barnes PJ. New concepts in chronic obstructive pulmonary disease. Ann Rev Med 2003; 54:113–129.
   PubMed Web of Science ®Google Scholar
• Cuciureanu M, Caruntu ID, Paduraru O, et al. The protective effect of Montelukast sodium on carbon tetrachloride induced hepatopathy in rat. Prostaglandins Other Lipid Mediat 2009; 88:82–88.
   PubMed Web of Science ®Google Scholar
• Sener G, Sehirli O, Ogunc AV, et al. 2006. Montelukast protects against renal ischemia/reperfusion injury in rats. Pharmacol Res 54:65–71.
   PubMed Web of Science ®Google Scholar
• Du J, Cui D, Guo Y. Detection of ET-1, TNF-alpha, oxidative radicals in sera of asthmatics and in sera and lung tissue of asthmatic guinea pigs. Zhonghua Jie He He Hu Xi Za Zhi 1998; 21(5):293–296.
   PubMedGoogle Scholar
• Tahan F, Jazrawi T, Rovati GE, Adcock IM. Montelukast inhibits tumour necrosis factor-α-mediated interleukin-8 expression through inhibition of nuclear factor-κB p65-­associated histone acetyltransferase activity. Clin Exp Allergy 2008; 38:805–811.
   PubMed Web of Science ®Google Scholar