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Review Article

Review: A Role for the FGF Receptor in the Axonal Growth Response Stimulated by Cell Adhesion Molecules?

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Pages 441-450 | Received 12 Jan 1996, Published online: 11 Jul 2009

References

  • Atashi J. R., Klinz S. G., Ingraham C. A., Matte W. T., Schachner M., Maness P. F. Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes. Neuron 1992; 8: 831–842
  • Baier H., Bonhoeffer F. Attractive axon guidance molecules. Science 1994; 265: 1541–1542
  • Bahler M., Greengard P. Synapsin 1 bundles F-actin in a phosphorylation dependent manner. Nature 1987; 326: 704–707
  • Bailey C. H., Chen M., Keller F., Kandel E. R. Serotonin mediated endocytosis of apCAM: an early step of learning-related synaptic growth in Aplysia. Science 1992; 258: 645–648
  • Baird A. Fibroblast growth factors: activities and significance of nonrneurotrophic growth factors. Curr. Op. Neurobiol. 1994; 4: 78–86
  • Beggs H. E., Soriano P., Maness P. F. NCAM dependent neurite outgrowth is inhibited in neurons from fynminus mice. J. Cell Biol. 1994; 127: 825–833
  • Bixby J. L., Pratt R. L., Lilien J., Reichardt L. F. Neurite outgrowth on muscle cell surfaces involves extracellular matrix receptors as well as Ca2+-dependent and independent cell adhesion molecules. Proc. Natl. Acad. Sci. USA 1987; 84: 2555–2569
  • Bixby J. L., Lilien J., Reichardt L. F. Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro. J. Cell Biol. 1988; 107: 353–361
  • Bixby J. L., Zhang R. Purified N-cadherin is a potent substrate for the rapid induction of neurite outgrowth. J. Cell Biol. 1990; 110: 1253–1260
  • Bixby J. L., Harris W. A. Molecular mechanisms of axon growth and guidance. Annu. Rev. Cell Biol. 1991; 7: 117–159
  • Bixby J. L., Grunwald G. B., Bookman R. J. Ca2+influx and neurite outgrowth in response to purified N-cadherin and laminin. J. Cell Biol. 1994; 127: 1461–1475
  • Chang S., Rathjen F. G., Raper J. A. Extension of neurites on axons is impaired by antibodies against specific neural cell surface glycoproteins. J. Cell Biol. 1987; 104: 355–362
  • Chuong C. M., Edelman G. M. Alterations in neural cell adhesion molecules during the development of different regions of the nervous system. J. Neurosci. 1984; 4: 2354–2368
  • Cole J. G., Akeson R. Identification of a heparin binding domain of the neural cell adhesion molecule N-CAM using synthetic peptides. Neuron 1989; 2: 1157–1165
  • Dodd J., Jessell T. M. Axon guidance and the patterning of neuronal projections in vertebrates. Science 1988; 242: 692–699
  • Doherty P., Barton C. H., Dickson G., Seaton P., Rowett L. H., Moore S. E., Gower H. J., Walsh F. S. Neural process outgrowth of human sensory neurons on monolayers of cells transfected with cDNAs for five human NCAM isoforms. J. Cell Biol. 1989; 109: 789–798
  • Doherty P., Cohen J., Walsh F. S. Neurite outgrowth in response to transfected NCAM changes during development and is modulated by polysialic acid. Neuron 1990a; 5: 209–219
  • Doherty P., Fruns M., Seaton P., Dickson G., Barton C. H., Sears T. A., Walsh F. S. A threshold effect of the major isoforms of NCAM on neurite outgrowth. Nature 1990b; 343: 464–466
  • Doherty P., Rowett L. H., Moore S. E., Mann D. A., Walsh F. S. Neurite outgrowth in response to transfected NCAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs. Neuron 1991a; 6: 247–258
  • Doherty P., Ashton S. V., Moore S. E., Walsh F. S. Morphoregulatory activities of N-CAM and N-cadherin can be accounted for G-protein dependent activation of L- and N-type neuronal calcium channels. Cell 1991b; 67: 21–33
  • Doherty P., Rimon G., Mann D. A., Walsh F. S. Alternative splicing of the cytoplasmatic domain of neural cell adhesion molecule alters its ability to act as a substrate for neurite outgrowth. J. Neurochem. 1992a; 58: 2338–2341
  • Doherty P., Moolenaar C. E. C. K., Ashton S. A., Michalides R. J. A. M., Walsh F. S. Use of the VASE exon down regulates the neurite growth promoting activity of NCAM 140. Nature 1992b; 356: 791–793
  • Doherty P., Furness J., Williams E. J., Walsh F. S. Neurite outgrowth stimulated by the tyrosine kinase inhibitor her-bimycin A requires activation of tyrosine kinases and protein kinase C. J. Neurochem. 1994; 62: 2124–2131
  • Doherty P., Walsh F. S. Signal transduction events underlying neurite outgrowth stimulated by cell adhesion molecules. Curr. Op. Neurobiol. 1994; 4: 49–55
  • Doherty P., Williams E. J., Walsh F. S. A soluble chimeric form of the L1 glycoprotein stimulates neurite outgrowth. Neuron 1995a; 14: 1–20
  • Doherty P., Fazeli M. S., Walsh F. S. The neural cell adhesion molecule and synaptic plasticity. J. Neurobiol. 1995b; 26: 437–446
  • Edelman G. M. Morphoregulatory molecules. Biochem. 1988; 27: 3533–3543
  • Edelman G. M. A golden age for Adhesion. Cell Adh. and Commun. 1993; 1: 1–7
  • Frei T., von Bohlen und Halbach F., Wille W., Schachner M. Different extracellular domains of the neural cell adhesion molecule (N-CAM) are involved in different functions. J. Cell biol. 1992; 118: 177–194
  • Ginsberg M. H., Du X., Plow E. F. Inside-out integrin signalling. Curr. Opin. Cell Biol. 1992; 4: 766–771
  • Goodman C. S., Shatz C. J. Developmental mechanisms that generate precise patterns of neuronal connectivity. Cell/Neuron 1993; 72/10(Suppl.)77–98
  • Goodman C. S. The likeliness of being: phylogenetically conserved molecular mechanisms of growth cone guidance. Cell 1994; 78: 353–356
  • Goldenring J. R., Gonzales B., McGuire J. S. J., DeLorenzo R. J. Purification and characterization of a calmodulin-dependent kinase from rat brain cytosol able to phosphorylate tubulin and microtubule associated proteins. J. Biol. Chem. 1983; 258: 12632–12640
  • Goshima Y., Nakamura F., Strittmatter P., Strittmatter S. M. Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33. Nature 1995; 376: 509–514
  • Grumet M. Cell adhesion molecules and their subgroups. Curr. Opin. Neurobiol. 1991; 1: 370–376
  • Grumet M., Flaccus A., Margolis R. Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules. J. Cell Biol. 1993; 120: 815–824
  • Hefti F., Hartikka J., Knusel B. Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases. Neurobiol. Aging 1989; 10: 515–533
  • Horwitz A., Duggan K., Buck C., Beckerle M. C., Burridge K. Interaction of plasma membrane fibronectin receptor with talin a transmembrane linkage. Nature 1986; 320: 531–532
  • Hynes R. O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11–25
  • Ignelzi M. A., Miller D. R., Soriano P., Maness P. F. Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1. Neuron 1994; 12: 873–884
  • Jaye M., Schlessinger J., Dionne C. A. Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction. Biochim. Biophys. Acta 1992; 1135: 185–199
  • Joyner A. L., Guillemot F. Gene targeting and development of the nervous system. Curr. Opin. Neurobiol. 1994; 4: 37–42
  • Kennedy T. E., Serafini T., de la Torre J. R., Tessier-Lavigne M. Netrins are diffusible chemotrophic factors for commissural axons in the embryonic spinal cord. Cell 1994; 78: 425–435
  • Keynes R., Cook G. M. W. Axon guidance molecules. Cell 1995; 83: 161–170
  • Klinz S. G., Schachner M., Maness P. F. L1 and N-CAM antibodies trigger protein phosphatase activity in growth cone-enriched membranes. J. Neurochem. 1995; 65: 84–95
  • Korsching S. The neurotrophic factor concept: a reexamination. J. Neurosci. 1993; 13: 2739–2748
  • Kuhn L. T., Stoeckli E. T., Confrau M. A., Rathjen F. G., Sonderegger P. Neurite outgrowth on immobilized axonin-1 is mediated by a heterophilic interaction with L1(G4). J. Cell Biol. 1991; 115: 1113–1126
  • Lagenauer G, Lemmon V. AL1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension. Proc. Natl. Acad. Sci. USA 1987; 84: 7753–7757
  • Landis S. C. Neuronal growth cones. Annu. Rev. Physiol. 1983; 45: 567–580
  • The nerve growth cone, P. C. Letourneau, S. B. M. E. R. Kater. Raven Press, New York 1991
  • Liu L., Haines S., Shaw R., Akeson R. A. Axon growth is enhanced by NCAM lacking the VASE exon when expressed in either the growth substrate or the growing axon. J. Neurosci. Res. 1993; 35: 327–345
  • Luo Y., Shepherd I., Li J., Renzi M. J., Chang S., Raper J. A. A family of molecules related to collapsin in the embrionic chick nervous system. Neuron 1995; 14: 1131–1140
  • Maness P. F. Nonreceptor protein tyrosine kinases associated with neuronal development. Dev. Neurosci. 1992; 14: 257–270
  • Mason I. Do adhesion molecules signal via FGF receptors?. Curr. Biol. 1994; 4: 1158–1161
  • Matsunaga M., Hatta K., Nagafuchi A., Takeichi M. Guidance of optic nerve fibers by N-cadherin adhesion molecules. Nature 1988; 334: 62–64
  • Marten W. T., Aubry M., West J., Maness P. F. Tubulin is phosphorylated at tyrosine by pp60c-src in nerve growth cone membranes. J. Cell Biol. 1990; 111: 1959–1970
  • Mayford M., Barzilai A., Keller A., Schauer K., Kandel E. R. Modulation of NCAM related adhesion molecule with long term synaptic plasticity in Aplysia. Science 1992; 256: 638–644
  • Moore S. E., Walsh F. S. Nerve dependent regulation of N-CAM expression in skeletal muscle. Neurosci. 1986; 18: 499–505
  • Murray B. A., Jensen J. J. Evidence of heterophilic adhesion of embryonic retinal cells and neuroblastoma cells to substrate- absorbed NCAM. J. Cell Biol. 1992; 117: 1311–1320
  • Neugebauer K. M., Tomaselli K. J., Lilien J., Reichardt L. F. N-cadherin, NCAM and integrins promote retinal neurite outgrowth on astrocytes in vitro. J. Cell Biol. 1988; 107: 1177–1187
  • Otey C. A., Pavalko F. M., Burridge K. An interaction of the α-actinin and the β1 integrin subunit in vitro. J. Cell Biol. 1990; 111: 721–729
  • Purves D., Lichtman J. W. Principles of neural development. Sinauer Associates Inc. 1985
  • Rathjen F. G., Schachner M. Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion. EMBO J. 1984a; 1: 1–10
  • Rathjen F. G., Jessell T. M. Glycoproteins that regulate the growth and guidance of vertebrate exons: domains and dynamics of the immunogobulin/fibronectin type III- subfamily. Semin. Neurosci. 1991; 3: 297–307
  • Reichardt L. F., Tomaselli K. J. Extracellular matrix molecules and their receptors: Functions in neural development. Annu. Rev. Neurosci. 1991; 14: 531–570
  • Retzka A. A., Hayashi Y., Horwitz A. F. Identification of amino acid sequences in the integrin β1 cytoplasmic domain implicated in cytosceletal association. J. Cell Biol. 1992; 117: 1321–1330
  • Sadoul K., Sadoul R., Faissner A., Schachner M. Biochemical characterization of different molecular forms of the neural cell adhesion molecule L1. J. Neurochem. 1988; 50: 510–521
  • Sadoul R., Kirchhoff F., Schachner M. A protein kinse activity is associated with and specifically phosphorylates the neural cell adhesion molecule L1. J. Neurochem. 1989; 53: 1471–1478
  • Saffell J. L., Walsh F. S., Doherty P. Direct activation of second messenger pathways mimics cell adhesion molecule-dependent neurite outgrowth. J. Cell Biol. 1992; 118: 663–67
  • Saffell J. L., Walsh F. S., Doherty P. Expression of NCAM containing VASE in neurons can account for a developmental loss in their neurite outgrowth response to NCAM in a cellular substratum. J. Cell Biol. 1994; 125: 427–436
  • Sanes J. Extracellular matrix molecules that influence neural development. Annu. Rev. Neurosci. 1989; 12: 491–516
  • Schlessinger J. L., Ullrich A. Growth factor signalling by receptor tyrosine kinases. Neuron 1992; 9: 383–391
  • Schuch U., Lohse M. J., Schachner M. Neural cell adhesion molecules influence second messenger systems. Neuron 1989; 3: 13–20
  • Seilheimer B., Schachner M. Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role of L1 in mediating sensory neuron growth on Schwann cells in culture. J. Cell Biol. 1988; 107: 341–351
  • Serafini T., Kennedy T. E., Galko M. J., Mirzayan C., Jessel T. M., Tessier-Lavigne M. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. Cell 1994; 78: 409–424
  • Small S. J., Harris S. L., Akeson R. Polypeptide variation in an NCAM extracellular fold is developmentally regulated through alternative splicing. Neuron 1988; 1: 1007–1017
  • Small S. J., Akeson R. Expression of the unique NCAM VASE exon is independently regulated in distinct tissues during development. J. Cell Biol. 1990; 111: 2089–2096
  • Sonderegger P., Rathjen F. G. Regulation of axonal growth in the vertebrate nervous system by interactions between glycoproteins belonging to two subgroups of the immunoglobulin superfamily. J. Cell Biol. 1992; 119: 1387–1394
  • Takeichi M. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development 1988; 102: 639–655
  • Takeichi M. Cadherins: a molecular family important in selective cell-cell adhesion. Annu. Rev. Biochem. 1990; 59: 237–252
  • Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 1991; 251: 1451–1455
  • Taplev P., Horwitz A. F., Buck C. A., Burridge K., Duggan K., Hirst R., Rohrschneider L. Analysis of the avian fibronectin receptor (integrin) as direct substrate for pp60src. Oncogen 1989; 4: 325–333
  • Tessier-Lavigne M. Axon guidance by diffusible repellents and attractants. Curr. Opin. Genet. Dev. 1994; 4: 596–601
  • Timpl R. Structure and biological activity of basement membrane proteins. Eur. J. Biochem. 1989; 180: 487–502
  • Tomaselli K. J., Reichardt R. F., Bixby J. L. Distinct molecular interactions mediate neuronal process outgrowth on non-neuronal cell surfaces and extracellular matrix. J. Cell Biol. 1986; 103: 2659–2672
  • Tomaselli K. J., Neugebauer K. N., Bixby J. L., Lilien J., Reichardt L. F. N-cadheins and integrins: two receptor systems that mediate neurite outgrowth on astrocyte surfaces. Neuron 1988; 1: 33–43
  • van der Geer P., Hunter T., Lindberg R. A. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 1994; 10: 251–337
  • von Bohlen und Halbach F., Taylor J., Schachner M. Cell type-specific effects of the neural adhesion molecules L1 and N-CAM on diverse second messenger systems. Eur. J. Neurosci. 1992; 4: 896–909
  • Walsh F. S., Doherty P. Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system. Cell Biol. Internat. Reports 1991; 15: 1151–1166
  • Williams E. J., Doherty P., Turner G., Reid R. A., Hemperley J. J., Walsh F. S. Calcium influx into neurons can solely account for cell-contact dependent neurite outgrowth stimulated by transfected L1. J. Cell Biol. 1992; 119: 885–892
  • Williams E. J., Furness J., Walsh F. S., Doherty P. Tyrosine kinase inhibitors can differentially inhibit integrin dependent and CAM stimulated neurite outgrowth. J. Cell Biol. 1994a; 124: 1029–1037
  • Williams E. J., Walsh F. S., Doderty P. Tyrosine kinase inhibitors can differentially inhibit integrin-dependent and CAM-stimulated neurite outgrowth. J. Cell Biol. 1994b; 124: 1029–1037
  • Williams E. J., Furness J., Walsh F. S., Doherty P. Characterization of the second messenger pathway underlying neurite outgrowth stimulated by FGF. Development 1994c; 120: 1685–1693
  • Williams E. J., Furness J., Walsh F. S., Doherty P. Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron 1994d; 13: 583–594
  • Williams E. J., Mittal B., Walsh F. S., Doherty P. A Ca2+/calmodulin kinase inhibitor, KN-62, inhibits neurite outgrowth stimulated by CAMs and FGF. Mol. Cell. Neurosci. 1995a; 6: 69–79
  • Williams E. J., Mittal B., Walsh F. S., Doherty P. FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules. J. Cell Science 1995b; 108: 3523–3530
  • Yurchenco P. D., Schittny J. C. Molecular architecture of the basement membranes. FASEB J. 1990; 4: 1577–1590

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