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Original Article

Regulation of Adhesion and Migration in the Germinal Center Microenvironment

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Pages 111-116 | Received 12 Feb 1998, Accepted 24 Apr 1998, Published online: 11 Jul 2009

References

  • Adams D. H., Hazvath L., Bottaro D. P., Interrante R., Catalano G., Tanaka Y., Strain A., Hubscher S. G., Shaw S. Hepatocyte growth factor and macrophage inflammatory protein 1β: Structurally distinct cytokines that induce rapid cytoskeletal changes and subset preferential migration in T cells. Proc. Natl. Acad. Sci. USA 1994; 91: 7144–7148
  • Arroyo A. G., Tang Y. T., Rayburn H., Hynes R. O. Differential requirements for α4 integrins during fetal and adult hematopoiesis. Cell 1996; 85: 997–1008
  • Banchereau J., Bazan F., Blanchard D., Briere F., Galizzi J. P., van Kooten C., Liu Y. J., Rousset F., Sealand S. The CD40 Ag and its ligand. Ann. Rev. Immunol. 1994; 12: 881–922
  • Berek C., Berger A., Apel M. Maturation of the immune response in germinal centers. Cell 1991; 67: 1121–1129
  • Brinkmann V., Foroutan H., Sachs M., Weidner K. M., Birchmeier W. Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells. J. Cell Biol. 1995; 31: 1573–1586
  • Bussolino F., Di Renzo M. F., Ziche M., Bocchietto E., Olivero M., Naldini L., Gaudino G., Tamagnone L., Coffer A., Comoglio P. M. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J. Cell Biol. 1992; 119: 629–641
  • Butcher E. C., Picker L. J. Lymphocyte homing and homeostasis. Science 1996; 272: 60–66
  • Casamayor-Palleja M., Khan M., MacLennan I. C.M. A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex. J. Exp. Med. 1995; 181: 1293–1301
  • Chen Q., DeFrances M. C., Zarnegar R. Induction of met proto-oncogene (hepatocyte growth factor receptor) expression during human monocyte-macrophage differentiation. Cell Growth Differ. 1996; 7: 821–832
  • Dapuzzo M., Rolink A., Loetscher M., Hoxie J. A., Clarklewis I., Melchers F., Baggiolini M., Moser B. The chemokine SDF-1, stromal cell-derived factor 1: attracts early stage B cell precursors via the chemokine receptor CXCR4. Eur. J. Immunol. 1997; 27: 1788–1793
  • Donate L. E., Gherardi E., Srinivasan N., Sowdhamini R., Aparicio S., Blundell T. L. Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP). Protein Science 1994; 3: 2378–2394
  • Facchetti F., Appiani C., Salvi L., Levy J., Notarangelo L. D. Immunohistologic analysis of ineffective CD40 CD40 ligand interaction in lymphoid tissues from patients with X-linked immunodeficiency with hyper-IgM. Abortive germinal center cell reaction and severe depletion of follicular dendritic cells. J. Immunol. 1995; 154: 6624–6633
  • Foester R., Mattis A. E., Kremmer E., Wolf E., Brem G., Lipp M. A putative chemokine receptor, BLRI, directs B cell migration to defined lymphoid organs and specific anatomical sites. Cell 1996; 87: 1037–1047
  • Foy T. M., Laman J. D., Ledbetter J. A., Aruffo A., Claasen E., Noelle R. J. gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. J. Exp. Med. 1994; 180: 157–163
  • Freedman AS., Munro J. M., Rice G. E., Bevilaqua M. P., Morimoto C., McIntyre B. W., Rhynheart K., Pober J. S., Nadler L. M. Adhesion of human B cells to germinal centers in vitro involves VLA-4 and INCAM-110. Science 1990; 249: 1030–1033
  • Fuller K. A., Kanagawa O., Nahm M. H. T cells within germinal centers are specific for the immunizing antigen. J. Immunol. 1993; 151: 4505–4512
  • Galimi F., Bagnara G. P., Bonsi L., Cottone E., Follenzi A., Simeone A., Comoglio P. M. Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors. J. Cell Biol. 1994; 127: 1743–1754
  • Giordano S., Zhen Z., Medico E., Gaudino G., Galmi F., Comoglio P. M. Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene. Proc. Natl. Acad. Sci. USA 1993; 90: 649–653
  • Han S., Hathcock K., Zheng B., Kepler R. B., Hodes R., Kelsoe G. Cellular interaction in germinal centres: Roles of CD40 ligand and B7-2 in established germinal centers. J. Immunol. 1995; 155: 556–567
  • Hardie D. L., Johnsons G. D., Khan M., MacLennan I. C.M. Quantitative analysis of molecules which distinguish functional compartments within germinal centers. Eur. J. Immunol. 1993; 23: 997–1004
  • Hynes R. O. Integrins: versatility, modulation, and signalling in cell adhesion. Cell 1992; 69: 11–25
  • Jacob J., Kassir R., Kelsoe G. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl) acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 1991; 173: 1165–1175
  • Jacob J., Kelsoe G., Rajewsky K., Weiss U. Intraclonal generation of antibody mutants in germinal centers. Nature 1991; 354: 389–392
  • Kelvin D., Michiel D. F., Johnston J. A., Lloyd A. R., Sprenger H., Oppenheim J. J., Wang J. M. Chemokines and serpentines: the molecular biology of chemokine receptors. J. Leukocyte Biol. 1993; 54: 604–612
  • Kmiecik T. E., Keller J. R., Rosen E., van de Woude G. F. Hepatocyte growth factor is a synergistic factor for the growth of hematopoietic progenitor cells. Blood 1992; 80: 2454–2457
  • Kawabe T., Naka T., Yoshida K., Tanaka T., Fujiwara H., Suematzu S., Yoshida N., Kishimoto T., Kikutani H. The immune response in CD40 deficient mice: Impaired immunoglobuline class switching and germinal center formation. Immunity 1994; 1: 167–178
  • Koopman G., Pals S. T. Cellular interactions in the germinal center: role of adhesion receptors and significance for the pathogenesis of AIDS and malignant lymphoma. Immunol. Rev. 1992; 126: 21–45
  • Koopman G., Parmentier H. K., Schuurman H. J., Newman W., Meijer C. J.L.M., Pals S. T. Adhesion of human B cells to follicular dendritic cells involves both the lymphocyte function-associated antigen-I/intercellular adhesion molecule l and very late antigen 4/vascular cell adhesion molecule 1 pathways. J. Exp. Med. 1991; 173: 1297–1304
  • Koopman G., Keehnen R. M.J., Lindhout E., Newman W., Shimizu Y., van Deventer G. A., de Groot C., Pals S. T. Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1(CD54) and the VLA-4 (CD69d)-VCAM-1(CD106) path-ways prevents apoptosis of germinal center B cells. J. Immunol. 1994; 152: 3760–3767
  • Koopman G., Keehnen R. M.J., Lindhout E., Zhou D. F.H., de Groot C., Pals S. T. Germinal center B cells rescued from apoptosis by CD40 ligation or attachment to follicular dendritic cells, but not by engagement of surface immunoglobulin or adhesion receptors, become resistant to CD95-induced apoptosis. Eur. J. Immunol. 1997; 27: 1–7
  • Kraal G., Weissman I. C., Butcher E. C. Germinal centre B cells: antigen specificity and changes in heavy chain class expression. Nature 1982; 298: 377–379
  • Küppers R., Zhao M., Hansmann H.-L., Rajewsky K. Tracing B cell development in human germinal centers by molecular analysis of single cells picked from histological sections. EMBO J. 1993; 12: 4955–4967
  • Liu Y. J., Zhang J., Lane P. J., Chan E. Y., MacLennan I. C. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 1991; 21: 2951–2961
  • Lindhout E., Koopman G., Pals S. T., de Groot C. Triple check for antigen specificity of B cells during germinal center reactions. Immunol. Today 1997; 18: 573–577
  • Liu Y. J., Grouard G., de Bouteiller O., Banchereau J. Follicular dendritic cells and germinal centers. Int. Rev. Cytol. 1996; 166: 139–179
  • Liu Y. J., Malisan F., de Bouteiller O., Guret C., Lebecque S., Banchereau J., Mills F. C., Max E. E., Martinez-Valdez H. Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. Immunity 1996; 4: 241–250
  • Loyd A. R., Oppenheim J. J., Kelvin D. J., Taub D. D. Chemokines regulate T cell adherence to recombinant adhesion molecules and extra-cellular matrix proteins. J. Immunol. 1996; 156: 932–938
  • MacLennan I. C.M. Germinal centers. Ann. Rev. Immunol. 1994; 12: 117–139
  • McHeyzer-Williams M. G., McLean M. J., Lalor P. A., Nossal G. J.V. Antigen-driven B cell differentiation, in vivo. J. Exp. Med. 1993; 178: 295–307
  • Miyaka K., Weissman I. L., Greenberger J. S., Kincade P. W. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J. Exp. Med. 1991; 173: 599–607
  • Mizuno K., Higuchi O., Ihle J. N., Nakamura T. Hepatocyte growth factor stimulates growth of hematopoietic progenitor cells. Biochemt. Biophys. Res. Commun. 1993; 194: 178–186
  • Montesano R., Matsumoto K., Nakamura T., Orci L. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 1991; 67: 901–908
  • Murphy P. M. The molecular biology of leukocyte chemoattractant receptors. Ann. Rev. Immunol. 1994; 12: 593–633
  • Nagasawa T., Nakajima T., Lizasa H., Bleul C. C., Yoshie O., Matsushima K., Yoshida H., Springer T. A., Kishimoto T. Molecular cloning and characterization of a murine pre-B-cell growth stimulating factor stromal cell-derived factor 1 receptor, a marine homolog of the human immunodeficiency virus entry coreceptor Fusin. Proc. Natl. Acad. Science USA 1996; 93: 14726–14729
  • Nakamura T., Nishizawa T., Hagiya M., Seki T., Shimonishi M., Sugimura A., Tashiro K., Shimizu S. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342: 440–443
  • Nishino T., Hisha H., Hishino N., Adachi M., Ikehara S. Hepatocyte growth factor as a hematopoietic regulator. Blood 1995; 85: 3093–3100
  • Nossal G. J.V., Abbot A., Mitchell J., Lummus Z. Ultrastructural features of antigen capture in primary and secondary lymphoid follicles. J. Exp. Med. 1968; 127: 277–290
  • Nossal G. J. Differentiation of the secondary B-lymphocyte repertoire: the germinal center reaction. Immunol. Rev. 1994; 137: 173–183
  • Nudelman E., Kannagi R., Hakomori S., Parsons M., Lipinski M., Wiels J., Fellous M., Tursz T. Science 1983; 220: 509–511
  • Oppenheim J. J., Zachariae C. O.C., Mukaida N., Matsushima K. Properties of the novel proinflammatory supergene “intercrine” cytokine family. Anna. Rev. Immunol. 1991; 9: 617–648
  • Pascual V., Liu Y. J., Magalski A., Bouteiller O., Banchereau J., Capra J. D. Analysis of somatic mutation in five B cell subsets of human tonsil. J. Exp. Med. 1994; 180: 329–339
  • Rajewski K. Clonal selection and learning in the antibody system. Nature 1996; 381: 751–758
  • Roldan E., Garcia-Pardo A., Brieva J. A. VLA-4 fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobulin secretion. J. Exp. Med. 1992; 175: 1739–1747
  • Rong S., Segal S., Anver M., Resau J. H., van de Woude G. F. Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. Proc. Natl. Acad. Sci. USA 1994; 91: 4731–4735
  • Ruoslahti E., Yamaguchi Y. Proteoglycans as modulators of growth factor activities. Cell 1991; 64: 867–869
  • Schall T. J., Bacon K. B. Chemokines, leukocyte trafficking, and inflammation. Curr. Opin. Immunol. 1994; 6: 865–873
  • Sonnenberg E., Meyer D., Weidner K. M., Birchmeier C. Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate signal exchange between mesenchyme and epithelia during mouse development. J. Cell Biol. 1993; 123: 223–235
  • Stoker M., Gherardi E., Perryman M., Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987; 327: 239–242
  • Tanaka Y., Adams D. H., Hubscher S., Hirano H., Siebenlist U., Shaw S. T cell adhesion induced by proteoglycan-immobilized cytokine MIP-1β. Nature 1993; 361: 79–83
  • Taub D. D., Conlon K., Lloyd A. R., Oppenheim J. J., Kelvin D. J. Preverential migration of activated CD4+ and CD8+ T cells in response to MIP-1α and MIP-1β. Science 1993; 260: 355–358
  • Tew J. G., Kosco M. H., Burton G. F., Szakal A. K. Follicular dendritic cells as accessory cells. Immunol. Rev. 1990; 117: 185–211
  • Thorbecke G. J., Amir A. R., Tsiagbe V. K. Biology of germinal centers in lymphoid tissue. FASEB J. 1994; 8: 832–840
  • van der Voort R., Taher T. E.I., Keehnen R. M.J., Smit L., Groenink M., Pals S. T. Paracrine regulation of germinal center B cell adhesion through the c-Met-hepatocyte growth factor/scatter factor pathway. J. Exp. Med. 1997; 185: 2121–2131
  • Wayner E. A., Carcia-Pardo A., Humphries M. J., McDonald J. A., Carter W. G. Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain in plasma fibronectin. J. Cell Biol. 1989; 109: 1321–1330
  • Weber C., Alon R., Moser B., Springer T. A. Sequential regulation of α4β1 and α5β1 integrin avidity by CC chemokines in monocytes: Implications for transendothelial chemotaxis. J. Cell Biol. 1996; 134: 1063–1073
  • Weidner K. M., Behrens J., Vandekerckhove J., Birchmeier W. Scatter Factor: molecular characteristics and effect on the invasiveness of epithelial cells. J. Cell Biol. 1990; 111: 2097–2108
  • Zheng B., Han S., Kelsoe G. T helper cells in murine germinal centers are antigen-specific emigrants that downregulate Thy-1. J. Exp. Med. 1996; 184: 1083–1091

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