77
Views
0
CrossRef citations to date
0
Altmetric
Original Article

Adhesion and Signaling Mediated by the Cytoplasmic Tails of Leucocyte Integrins

, &
Pages 247-254 | Received 12 Feb 1998, Accepted 28 Apr 1998, Published online: 11 Jul 2009

References

  • Arroyo A. G. Induction of tyrosine phosphorylation during ICAM-3 and LFA-l-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase. J. Cell Biol. 1994; 126: 1277–1286
  • Bernard G. Engagement of the CD45 molecule induces homotypic adhesion of human thymocytes through a LFA-1/ICAM-3-Dependent pathway. Journal of Immunology 1994; 152: 5161–5170
  • Berton G. Beta 2 integrin-dependent protein tyro-sine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils. J. Cell Biol. 1994; 126: 1111–1121
  • Blystone S. D. Inducible tyrosine phosphorylation of the beta(3) integrin requires the alpha(V) integrin cytoplasmic tail. J. Biol. Chem. 1996; 271: 31458–31462
  • Cambier J. C. New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL). Immunology Today 1995; 16: 110
  • Chan A. C. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu. Rev. Immunol. 1994; 12: 555–592
  • Chen Y. P. Ser-752 → Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia. Proc. Natl. Acad. Sci. USA 1992; 89: 10169–10173
  • Chen Y. P. A point mutation in the integrin beta(3) cytoplasmic domain (S752-p) impairs bidirectional signaling through alpha IIb beta P3 (platelet glycoprotein IIb-IIIa). Blood 1994; 84: 1857–1865
  • Clark E. A. Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3. J. Biol. Chem. 1994; 269: 28859–28864
  • Collins T. L. Adhesion receptors in lymphocyte activation. Curr. Opin. Immunol. 1994; 6: 385–393
  • Coppolino M. Inducible interaction of integrin alpha(2)beta(l) with calreticulin – Dependence on the activation state of the integrin. J. Biol. Chem. 1995; 270: 23132–23138
  • Coppolino M. G. Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion. Nature 1997; 386: 843–847
  • Dedhar S. Novel functions for calreticulin: interaction with integrins and modulation of gene expression?. Trends Biochem. Sci. 1994; 19: 269–271
  • Dedhar S. Integrin cytoplasmic interactions and bidirectional transmembrane signaling. Curr. Opin. Cell Biol. 1996; 8: 657–669
  • Du X. P. Calpain cleavage of the cytoplasmic domain of the integrin beta(3) subunit. J. Biol. Chem. 1995; 270: 26146–26151
  • Elemer G. S. Microfilament reorganization is associated with functional activation of alpha(M)beta(2) on monocytic cells. J. Biol. Chem. 1994; 269: 3159–3166
  • Fan S. T. CD11a/CD18 (LFA-1) integrin engagement enhances biosynthesis of early cytokines by activated T cells. Cellular Immunology 1993; 148: 48–59
  • Felsenfeld D. P. Ligand binding regulates the directed movement of beta 1 integrins on fibroblasts. Nature 1996; 383: 438–440
  • Figdor C. G. On the mode of action of LFA-1. Immunology Today 1990; 11: 277–280
  • Frangioni J. V. Calpain-catalyzed cleavage and subcellular relocation of protein phosphotyrosine phosphatase 1B (PTP-1B) in human platelets. The EMBO Journal 1993; 12: 4843–4856
  • Fujii C. Involvement of protein-tyrosine kinase p72syk in collagen-induced signal transduction in platelets. European Journal of Biochemistry 1994; 226: 243–248
  • Gorlin J. B. Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. J. Cell Biol. 1990; 111: 1089–1105
  • Haskill S. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. Cell 1991; 65: 1281–1289
  • Hughes P. E. The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity. J. Biol. Chem. 1995; 270: 12411–12417
  • Klarlund J. K. Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains (see comments). Science 1997; 275: 1927–1930
  • Kolanus W. Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-l, a cytoplasmic regulatory molecule. Cell 1996; 86: 233–242
  • Koopman G. Adhesion through the LFA-1 (Cd11A/CD18)-ICAM-1 (Cd54) and the VLA-4 (Cd49D)-Vcam-1 (Cd106) pathways prevents apoptosis of germinal center B cells. Journal of Immunology 1994; 152: 3760–3767
  • Kucik D. F. Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes. J. Clin. Invest. 1996; 97: 2139–2144
  • Lauffenburger D. A. Cell motility – Making connections count. Nature 1996; 383: 390–391
  • Law D. A. Outside-in integrin signal transduction – alpha(IIb)beta(3)-(GP IIb-IIIa) tyrosine phosphorylation induced by platelet aggregation. J. Biol. Chem. 1996; 271: 10811–10815
  • Lo S. H. Tensin: a potential link between the cytoskeleton and signal transduction. Bioassays 1994; 16: 817–823
  • Lowell C. A. Deficiency of Src family kinases p59/ 61(hck) and p58(c- fgr) results in defective adhesion-dependent neutrophil functions. J. Cell Biol. 1996; 133: 895–910
  • Lub M. Ins and outs of LFA-1. Immunology Today 1995; 16: 479–483
  • Lub M. Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1. Mol. Biol. Cell 1997a; 8: 341–351
  • Lub M. The cytoplasmic tail of beta-1, beta-2 and beta-3 integrins differentially regulate LFA-1 function in K562 cells. Mol. Biol. Cell 1997–96; 8: 719–728
  • Mauro L. J. 'Zip codes' direct intracellular protein tyrosine phosphatases to the correct cellular 'address'. Trends Biochem. Sci. 1994; 19: 151–155
  • Mayer B. J. Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases. Current Biology 1995; 5: 296–305
  • Mengaud J. E-cadherin is the receptor for internalin, a surface protein required for entry of L-monocytogenes into epithelial cells. Cell 1996; 84: 923–932
  • Minegishi M. Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta I integrin-mediated signaling in lymphocytes. J. Exp. Med. 1996; 184: 1365–1375
  • Miyamoto S. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 1995a; 267: 883–885
  • Miyamoto S. Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules. J. Cell Biol. 1995b; 131: 791–805
  • Moy V. T. Signaling by lymphocyte function-associated antigen 1 (LFA-1) in B cells: enhanced antigen presentation after stimulation through LFA-1. J. Exp. Med. 1992; 175: 1–7
  • Mustelin T. Regulation of the p70zap tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase. European Journal of Immunology 1995; 25: 942–946
  • Nojima Y. Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130(Cas), a Src homology 3-containing molecule having multiple Src homology 2-binding motifs. J. Biol. Chem. 1995; 270: 15398–15402
  • O'Toole T. E. Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain. J. Biol. Chem. 1995; 270: 8553–8558
  • Pardi R. Regulatory mechanisms in leukocyte adhesion: flexible receptors for sophisticated travelers. Immunology Today 1992; 13: 224–230
  • Pavalko F. M. Activation of human neutrophils induces an interaction between the integrin β2-subunit (CD18) and the actin binding protein α-actinin. Journal of Immunology 1993; 151: 3795–3807
  • Pawson T. Protein modules and signalling networks. Nature 1995; 373: 573–580
  • Peter K. Modulation of cell adhesion by changes in alpha(L)beta(2) (LFA-1, CD11a/CD18) cytoplasmic domain/ cytoskeleton interaction. J. Exp. Med. 1995; 181: 315–326
  • Petruzzelli L. Adhesion through the interaction of lymphocyte function-associated antigen-1 with intracellular adhesion molecule-1 induces tyrosine phosphorylation of p130(cas) and its association with c-CrkII. J. Biol. Chem. 1996; 271: 7796–7801
  • Polte T. R. Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130(Cas). Proc. Natl. Acad. Sci. USA 1995; 92: 10678–10682
  • Reszka A. A. Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association. J. Cell Biol. 1992; 117: 1321–1330
  • Ribon V. The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner. Mol. Cell Biol. 1996; 16: 45–52
  • Roberts K. The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/ delta T cells. J. Exp. Med. 1991; 173: 231–240
  • Schaller M. D. Autophosphorylation of the focal adhesion kinase, Pp125(Fak), directs Sh2 dependent binding of Pp60(SRC). Mol. Cell Biol. 1994; 14: 1680–1688
  • Schaller M. D. Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains. J. Cell Biol. 1995a; 130: 1181–1187
  • Schaller M. D. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol. Cell Biol. 1995b; 15: 2635–2645
  • Sharma C. P. Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18. Journal of Immunology 1995; 154: 3461–3470
  • Shattil S. J. Adhesive signaling in platelets. Curr. Opin. Cell Biol. 1994; 6: 695–704
  • Shattil S. J. Function and regulation of the beta 3 integrins in hemostasis and vascular biology. Thromb. Haemost. 1995; 74: 149–155
  • Shattil S. J. Beta(3)-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta(3) subunit. J. Cell Biol. 1995; 131: 807–816
  • Sonnenberg A. Integrins and their ligands. Curr. Top. Microbiol. Immunol. 1993; 184: 7–35
  • Stossel T. P. On the crawling of animal cells. Science 1993; 260: 1086–1094
  • Streuli M. Protein tyrosine phosphatases in signalling. Curr. Opin. Cell Biol. 1996; 8: 182–188
  • Tohyama Y. Translocation of p72syk to the cytoskeleton in thrombin-stimulated platelets. J. Biol. Chem. 1994; 269: 32796–32799
  • Trowbridge I. S. CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 1994; 12: 85–116
  • Turner C. E. Paxillin: a cytoskeletal target for tyrosine kinases. Bioessays 1994; 16: 47–52
  • Van Seventer G. A. Roles of multiple accessory molecules in T-cell activation. Curr. Opin. Immunol. 1991; 3: 294–303
  • Vuori K. Tyrosine phosphorylation of p130(Cas) and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix. J. Biol. Chem. 1995; 270: 22259–22262
  • Yamada A. Activation of human CD4 T lymphocytes. Interaction of fibronectin with VLA-5 receptor on CD4 cells induces the AP-l transcription factor. Journal of Immunology 1991; 146: 53–56
  • Yurochko A. D. Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction. Proc. Natl. Acad. Sci. USA 1992; 89: 9034–9038
  • Zapata J. M. B-cell homotypic adhesion through exon-A restricted epitopes of CD45 involves LPA-1/ICAM-1, ICAM-3 interactions, and induces coclustering of CD45 and LFA-1. Blood 1995; 86: 1861–1872

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.