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Research Article

Intravenous anesthetic propofol suppresses prostaglandin E2 production in murine dendritic cells

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Pages 359-366 | Received 20 Jun 2011, Accepted 30 Aug 2011, Published online: 28 Oct 2011

References

  • Ahrens J., Haeseler G., Leuwer M., Mohammadi B., Krampfl K., Dengler R., and Bufler J. 2004. butylphenol, a non-anesthetic propofol analog, modulates α1β glycine receptor function in a manner distinct from propofol. Anesth. Analg. 99:91–96.
  • Alam S., Laughton D. L., Walding A., andWolstenholme A. J. 2006. Human peripheral blood mononuclear cells express GABAA receptor subunits. Mol. Immunol. 43:1432–1442.
  • Bali M., andAkabas M. H. 2004. Defining the propofol binding site location on the GABAA receptor. Mol. Pharmacol. 65:68–76.
  • Baratelli F. E., Heuze-Vourc’h N., Krysan K., Dohadwala M., Riedl K., Sharma S., andDubinett S. M. 2004. Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix. J. Immunol. 173:5458–5466.
  • Bjurstom H., Wang J., Ericsson I., Bengtsson M., Liu Y., Kumar-Mendu S., Issazadeh-Navikas S., and Birnir B. 2008. GABA, a natural immunomodulator of T-lymphocytes. J. Neuroimmunol. 205:44–50.
  • Byrum R. S., Goulet J. L., Snouwaert J. N., Griffiths R. J., andKoller B. H. 1999. Determination of the contribution of cysteinyl leukotrienes and leukotriene B4 in acute inflammatory responses using 5-lipoxygenase- and leukotriene A4 hydrolase-deficient mice. J. Immunol. 163:6810–6819.
  • Fogel-Petrovic M., Long J. A., Knight D. A., Thompson P. J., andUpham J. W. 2004. Activated human dendritic cells express inducible cyclo-oxygenase and synthesize prostaglandin E2 but not prostaglandin D2. Immunol. Cell Biol. 82:47–54.
  • Gualde N., and Harizi H. 2004. Prostanoids and their receptors that modulate dendritic cell-mediated immunity. Immunol. Cell Biol. 82:353–360.
  • Harizi H., and Gualde N. 2002. Dendritic cells produce eicosanoids, which modulate generation and functions of antigen-presenting cells. Prostagland. Leukotriene Essent. Fatty Acids 66:459–466.
  • Harizi H., Juzan M., Pitard V., Moreau J. F., andGualde N. 2002. Cyclo-oxygenase-2-issued prostaglandin E2 enhances the production of endogenous IL-10, which down-regulates dendritic cell functions. J. Immunol. 168:2255–2263.
  • Henderson W. R.Jr, . 1994. The role of leukotrienes in inflammation. Ann. Intern. Med. 121:684–697.
  • Inada T., Kubo K., and Shingu K. 2010. Promotion of interferon-γ production by natural killer cells via suppression of murine peritoneal macrophage prostaglandin E production using intravenous anesthetic propofol. Int. Immunopharmacol. 10:1200–1208.
  • Jiang Q., Elson-Schwab I., Courtemanche C., andAmes B. N. 2000. γ-Tocopherol and its major metabolite, in contrast to α-tocopherol, inhibit cyclo-oxygenase activity in macro- phages and epithelial cells. Proc. Natl. Acad. Sci. USA 97:11494–11499.
  • Jozefowski S., Biedron R., Bobek M., and Marcinkiewicz J. 2005. Leukotrienes modulate cytokine release from dendritic cells. Immunology 116:418–428.
  • Jozefowski S., Bobek M., and Marcinkiewicz J. 2003. Exogenous but not endogenous prostanoids regulate cytokine secretion from murine bone marrow dendritic cells: EP2, DP, and IP but not EP1, EP3, and FP prostanoid receptors are involved. Int. Immunopharmacol. 3:865–878.
  • Jung I. D., Jeong Y. I., Lee C. M., Noh K. T., Jeong S. K., Chun S. H., Choi O. H., Park W. S., Han J., Shin Y. K., Kim H. W., Yun C. H., andPark Y. M. 2010. COX-2 and PGE2 signaling is essential for the regulation of IDO expression by curcumin in murine bone marrow-derived dendritic cells. Int. Immunopharmacol. 10:760–768.
  • Lee M., Schwab C., andMcGeer P. L. 2011. Astrocytes are GABAergic cells that modulate microglial activity. Glia 59:152–165.
  • Lutz M. B., Kukutsch N., Ogilvie A. L., Rossner S., Koch F., Romani N., andSchuler G. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Meth. 223:77–92.
  • Machida I., Matsuse H., Kondo Y., Kawano T., Saeki S., Tomari S., Obase Y., Fukushima C., and Kohno S. 2004. Cysteinyl leukotrienes regulate dendritic cell functions in a murine model of asthma. J. Immunol. 172:1833–1838.
  • Mak T., andSaunders M. E. (Eds.). 2006. The Immune Response: Basic and Clinical Principles. Burlington, VT: Elsevier Academic Press.
  • Needleman P., Turk J., Jakschik B. A., Morrison A. R., andLefkowith J. B. 1986. Arachidonic acid metabolism. Annu. Rev. Biochem. 55:69–102.
  • Norgauer J., Ibig Y., Gmeiner D., Herouy Y., andFiebich B. L. 2003. Prostaglandin E2 synthesis in human monocyte-derived dendritic cells. Int. J. Mol. Med. 12:83–86.
  • Otto J. C., andSmith W. L. 1995. Prostaglandin endoperoxide synthases-1 and -2. J. Lipid Mediat. Cell Signal. 12:139–156.
  • Rigouzzo A., Girault L., Louvet N., Servin F., De-Smet T., Piat V., Seeman R., Murat I., and Constant I. 2008. The relationship between bi-spectral index and propofol during target-controlled infusion anesthesia: A comparative study between children and young adults. Anesth. Analg. 106:1109–1116.
  • Robbiani D. F., Finch R. A., Jager D., Muller W. A., Sartorelli A. C., andRandolph G. J. 2000. The leukotriene C4 transporter MRP1 regulates CCL19 (MIP-3β, ELC)-dependent mobilization of dendritic cells to lymph nodes. Cell 103:757–768.
  • Ruitenberg J. J., andWaters C. A. 2003. A rapid flow cytometric method for the detection of intracellular cyclooxygenases in human whole blood monocytes and a COX-2-inducible human cell line. J. Immunol. Meth. 274:93–104.
  • Sa-Nunes A., Bafica A., Lucas D. A., Conrads T. P., Veenstra T. D., Andersen J. F., Mather T. N., Ribeiro J. M., andFrancischetti I. M. 2007. Prostaglandin E2 is a major inhibitor of dendritic cell maturation and function in Ixodes scapularis saliva. J. Immunol. 179:1497–1505.
  • Scandella E., Men Y., Gillessen S., Forster R., and Groettrup M. 2002. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 100:1354–1361.
  • Shiraishi H., Yoshida H., Saeki K., Miura Y., Watanabe S., Ishizaki T., Hashimoto M., Takaesu G., Kobayashi T., and Yoshimura A. 2008. Prostaglandin E2 is a major soluble factor produced by stromal cells for preventing inflammatory cytokine production from dendritic cells. Int. Immunol. 20:1219–1229.
  • Sompayrac L. (Ed.). 2003. How the Immune System Works? Malden, MA: Blackwell Publishing.
  • Son Y., Ito T., Ozaki Y., Tanijiri T., Yokoi T., Nakamura K., Takebayashi M., Amakawa R., and Fukuhara S. 2006. Prostaglandin E2 is a negative regulator on human plasmacytoid dendritic cells. Immunology 119:36–42.
  • Tilley S. L., Coffman T. M., andKoller B. H. 2001. Mixed messages: Modulation of inflammation and immune responses by prostaglandins and thromboxanes. J. Clin. Invest. 108:15–23.
  • van der Pouw Kraan T. C., Boeije L. C., Smeenk R. J., Wijdenes J., andAarden L. A. 1995. Prostaglandin-E2 is a potent inhibitor of human IL-12 production. J. Exp. Med. 181:775–779.
  • Vanlersberghe C., and Camu F. 2008. Propofol. Handbook Exp. Pharmacol. 182:227–252.
  • Yao C., Sakata D., Esaki Y., Li Y., Matsuoka T., Kuroiwa K., Sugimoto Y., and Narumiya S. 2009. Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion. Nat. Med. 15:633–640.

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