Oral warfarin affects peripheral blood leukocyte IL-6 and TNFα production in rats

References

• Ad-El, D. D., Meirovitz, A., Weinberg, A., Kogan, L., Arieli, D., Neuman, A.Linton, D. 2000. Warfarin skin necrosis: Local and systemic factors. Br. J. Plast. Surg. 53:624–626.
   PubMedGoogle Scholar
• Becker, R. C. 2007. Warfarin-induced vasculopathy. J. Thromb. Thrombolysis 23:79–81.
   PubMed Web of Science ®Google Scholar
• Belij, S., Miljković, D., Popov, A., Subota, V., Timotijević, G., Slavić, M., Mirkov I., Kataranovski, D. Kataranovski, M. 2012. Effects of subacute oral warfarin administration on peripheral blood granulocytes in rats. Food Chem. Toxicol. 50:1499–1507.
   PubMed Web of Science ®Google Scholar
• Berkarda, B., Bouffard-Eyüboglu, H. Derman, U. 1983. The effect of coumarin derivatives on the immunological system of man. Agents Actions 13:50–52.
   PubMedGoogle Scholar
• Berkarda, B., Marrack, P., Kappler, J. W. Bakemeier, R. F. 1978. Effects of warfarin administration on the immune response of mice. Arzneimittelforschung 28:1407–1410.
   PubMed Web of Science ®Google Scholar
• Bobek, V.Kovarik, J. 2004. Anti-tumor and anti-metastatic effect of warfarin and heparins. Biomed. Pharmacother. 58:213–219.
   PubMed Web of Science ®Google Scholar
• Bobek, V., Boubelik, M., Fiserova, A., L’uptovcova, M., Vannucci, L., Kacprzak, G., Kolodzej, J., Majewski, A. M.Hoffman, R. M. 2005. Anti-coagulant drugs increase natural killer cell activity in lung cancer. Lung Cancer 47:215–223.
   PubMed Web of Science ®Google Scholar
• Choi, H. S., Kim, J. W., Cha, Y. N. Kim, C. 2006. A quantitative nitroblue tetrazolium assay for determining intracellular superoxide anion production in phagocytic cells. J. Immunoassay Immunochem. 27:31–44.
   PubMed Web of Science ®Google Scholar
• Edwards, R. L.Rickles, F. R. 1978. Delayed hypersensitivity in man: Effects of systemic anti-coagulation. Science 200:541–543.
   PubMed Web of Science ®Google Scholar
• Eichbaum, F. W., Slemer, O.Zyngier, S. B. 1979. Anti-inflammatory effect of warfarin and Vitamin K1. Naunyn. Schmiedebergs. Arch. Pharmacol. 307:185–190.
   PubMed Web of Science ®Google Scholar
• Furie, B. 2000. Oral anti-coagulant therapy. In: Hematology. Basic Principle and Practice (Hoffman, R., Benz, E. J., Shatill, S. J., V, B., Cohen, J. H., Silberstein, L. E.McGlave, P., Eds.). London: Churchill Livingstone/Harcourt Health Science Co, pp. 2040–2046.
   Google Scholar
• Hallett, M. B.Lloyds, D. 1995. Neutrophil priming: The cellular signals that say ‘amber’ but not ‘green’. Immunol. Today 16:264–268.
   PubMedGoogle Scholar
• Hermes, B., Haas, N.Henz, B. M. 1997. Immunopathological events of adverse cutaneous reactions to coumarin and heparin. Acta. Derm. Venereol. 77:35–38.
   PubMed Web of Science ®Google Scholar
• Hirsh, J., Dalen, J. E., Anderson, D. R., Poller, L., Bussey, H., Ansell, J., Deykin, D. Brandt, J. T. 1998. Oral anti-coagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 114:445S–469S.
   PubMed Web of Science ®Google Scholar
• Howe, A. M.Webster, W. S. 2000. Warfarin exposure and calcification of the arterial system in the rat. Int. J. Exp. Pathol. 81:51–56.
   PubMed Web of Science ®Google Scholar
• Jo, Y. M., Park, T. H., Jeong, I. H., Kim, H. J., Ahn, J. H., Kim, W. J., Cho, Y. R., Baek, H. K., Kim, M. H. Kim, Y. D. 2011. Warfarin-induced eosinophilic pleural effusion. Korean Circ. J. 41:109–112.
   PubMed Web of Science ®Google Scholar
• Kapoor, K. G.Bekaii-Saab, T. 2008. Warfarin-induced allergic interstitial nephritis and leucocytoclastic vasculitis. Intern. Med. J. 38:281–283.
   PubMed Web of Science ®Google Scholar
• Kataranovski, D., Savić, I. R., Kataranovski, M. Soldatović, B. 1988. Trombelastography and the six-day-test as reliable methodological aproaches to the discovery of resistance towards anti-coagulant rodenticides in the Norway rat (Rattus norvegicus BERKENHOUT, 1769). Acta Veterin. 38:3–12.
   Web of Science ®Google Scholar
• Kataranovski, M., Kataranovski, D., Zolotarevski, L., Jovic, M. 2007a. Epicutaneous exposure to anti-coagulant rodenticide warfarin modulates local skin activity in rats. Cut. Ocul. Toxicol. 26:1–13.
   PubMed Web of Science ®Google Scholar
• Kataranovski, M., Mirkov, I., Vranković, J., Kataranovski, D. Subota, V. 2008. Percutaneous toxicity of anti-coagulant warfarin in rats. Cutan. Ocul. Toxicol. 27:29–40.
   PubMed Web of Science ®Google Scholar
• Kataranovski, M., Prokić, V., Kataranovski, D., Zolotarevski, L. Majstorović, I. 2005. Dermatotoxicity of epicutaneously-applied anti-coagulant warfarin. Toxicology 212:206–218.
   PubMed Web of Science ®Google Scholar
• Kataranovski, M., Vlaški, M., Kataranovski, D., Tošić, N., Mandić-Radić, S.Todorović, V. 2003. Immunotoxicity of epicutaneously-applied anti-coagulant rodenticide warfarin: Evaluation by contact hypersensitivity to DNCB in rats. Toxicology 188:83–100.
   PubMed Web of Science ®Google Scholar
• Kataranovski, M., Živanović, J., Vranković, J., Mirkov, I.Kataranovski, D. 2007b. Granulocyte-stimulating activity of the anti-coagulant warfarin in rats. Arch. Biol. Sci. 59:53–54.
   Google Scholar
• Kater, A. P., Peppelenbosch, M. P., Brandjes, D. P.Lumbantobing, M. 2002. Dichotomal effect of the coumadin derivative warfarin on inflammatory signal transduction. Clin. Diagn. Lab. Immunol. 9:1396–1397.
   PubMedGoogle Scholar
• Kuebler, W. M. 2005. Inflammatory pathways and microvascular responses in the lung. Pharmacol. Rep. 57(Suppl):196–205.
   PubMedGoogle Scholar
• Kurohara, M., Yasuda, H., Moriyama, H., Nakayama, M., Sakata, M., Yamada, K., Kotani, R., Hara, K., Yokono, K.Nagata, M. 2008. Low-dose warfarin functions as an immunomodulator to prevent cyclophosphamide-induced NOD diabetes. Kobe J. Med. Sci. 54:E1–E13.
   PubMedGoogle Scholar
• Kuwahara, T., Hamada, M., Inoue, Y., Aono, S.Hiwada, K. 1995. Warfarin–induced eosinophilic pleurisy. Intern. Med. 34:794–796.
   PubMed Web of Science ®Google Scholar
• Lund, M. 1988. Anti-coagulant rodenticides. In: Rodent Pest Management (Prakash, I. , Ed.). Boca Raton, FL: CRC Press, pp. 341–351.
   Google Scholar
• Nakano, T., Kawamoto, K., Kishino, J., Nomura, K., Higashino, K. Arita, H. 1997. Requirement of γ-carboxyglutamic acid residues for the biological activity of Gas6: Contribution of endogenous Gas6 to the proliferation of vascular smooth muscle cells. Biochem. J. 323:387–392.
   PubMed Web of Science ®Google Scholar
• Nakchbandi, W., Müller, H., Singer, M. V., Löhr, M. Nakchbandi, I. A. 2006. Effects of low-dose warfarin and regional chemotherapy on survival in patients with pancreatic carcinoma. Scand. J. Gastroenterol. 41:1095–1104.
   PubMed Web of Science ®Google Scholar
• Oez, S., Platzer, E. Welte, K. 1990. A quantitative colorimetric method to evaluate the functional state of human polymorphonuclear leukocytes. Blut. 60:97–102.
   PubMedGoogle Scholar
• Perez, R. L., Roman, J., Staton, G. W, Jr., and Hunter, R. L. 1994. Extravascular coagulation and fibrinolysis in murine lung inflammation induced by the mycobacterial cord factor trehalose-6,6′-dimycolate. Am. J. Respir. Crit. Care Med. 149:510–518.
   PubMed Web of Science ®Google Scholar
• Poli, D., Antonucci, E., Gensini, G. F., Abbate, R.Prisco, D. 2003. Asymptomatic excessive coumarin anti-coagulation is a risk factor for thrombotic and bleeding complications of oral anti-coagulant therapy. J. Thromb. Haemost. 1:1840–1841.
   PubMed Web of Science ®Google Scholar
• Popov, A., Mirkov, I., Zolotarevski, L., Jović, M., Belij, S., Kataranovski, D.Kataranovski, M. 2011. Local pro-inflammatory effects of repeated skin exposure to warfarin, an anti-coagulant rodenticide in rats. Biomed. Environ. Sci. 24:180–189.
   PubMed Web of Science ®Google Scholar
• Price, P. A. 1988. Role of Vitamin-K-dependent proteins in bone metabolism. Annu. Rev. Nutr. 8:565–583.
   PubMed Web of Science ®Google Scholar
• Reagan-Shaw, S., Nihal, M.Ahmad, N. 2007. Dose translation from animal to human studies revisited. FASEB J. 22:659–661
   PubMed Web of Science ®Google Scholar
• Shearer, M. J. 1990. Vitamin K and Vitamin K-dependent proteins. Br. J. Hematol. 75:156–162.
   PubMed Web of Science ®Google Scholar
• World Health Organization (WHO). 1995. Anti-coagulant Rodenticides. (Environmental Health Criteria, No. 175) Geneva: WHO, pp. 1–121.
   Google Scholar
• Yanagita, M., Ishii, K., Ozaki, H., Arai, H., Nakano, T., Ohashi, K., Mizuno, K., Kita, T.Doi, T. 1999. Mechanism of inhibitory effect of warfarin on mesangial cell proliferation. J. Am. Soc. Nephrol. 10:2503–2509.
   PubMed Web of Science ®Google Scholar