1,336
Views
34
CrossRef citations to date
0
Altmetric
Research Article

Amelioration of Ochratoxin A-induced immunotoxic effects by silymarin and vitamin E in White Leghorn cockerels

, , , &
Pages 25-31 | Received 22 Jan 2012, Accepted 15 Apr 2012, Published online: 26 Jun 2012

References

  • Ajakaiye, J. J., Cuesta-Mazorra, M. Garcia-Diaz, J. R. 2011. Vitamins C and E can alleviate adverse effects of heat stress on live weight and some egg quality profiles of layer hens. Pak. Vet. J. 31:45–49.
  • Alidoost, F., Gharagozloo, M., Bagherpour, B., Jafarian, A., Sajjadi, SE., Hourfar, H Moayedi, B. 2006. Effects of silymarin on the proliferation and glutathione levels of peripheral blood mononuclear cells from beta-thalassemia major patients. Int. Immunopharmacol. 6:1305–1310.
  • Akhtar, M., Hafeez, M. A., Muhammad, F., Haq, A. Anwar, M. I. 2008. Immunomodulatory and protective effects of sugar cane juice in chickens against Eimeria infection. Turk. J. Vet. Anim. Sci. 32:463–467.
  • Al-Anati, L., Essid, E., Reinehr, R. Petzinger, E. 2009. Silibinin protects OTA-mediated TNF-alpha release from perfused rat livers and isolated rat Kupffer cells. Mol. Nutr. Food. Res. 53:460–466.
  • Alvarez-Erviti, L., Leache, C., González-Peñas, E. de Cerain, AL. 2005. Alterations induced in vitro by ochratoxin A in rat lymphoid cells. Hum. Exp. Toxicol. 24:459–466.
  • Atroshi, F., Biese, I., Saloniemi, H., Ali-Vehmas, T., Saari, S., Rizzo, A. Veijalainen, P. 2000. Significance of apoptosis and its relationship to antioxidants after ochratoxin A administration in mice. J. Pharm. Pharm. Sci. 3:281–291.
  • Baldi, A., Losio, M. N., Cheli, F., Rebucci, R., Sangalli, L., Fusi, E., Bertasi, B., Pavoni, E., Carli, S. Politis, I. 2004. Evaluation of the protective effects of alpha-tocopherol and retinol against ochratoxin A cytotoxicity. Br. J. Nutr. 91:507–512.
  • Bayman, P., Baker, J. L., Doster, M. A., Michailides, T. J. Mahoney, N. E. 2002. Ochratoxin production by the Aspergillus ochraceus group and Aspergillus alliaceus. Appl. Environ. Microbiol. 68:2326–2329.
  • Campbell, M. L. Jr, May, J. D., Huff, W. E. Doerr, J. A. 1983. Evaluation of immunity of young broiler chickens during simultaneous aflatoxicosis and ochratoxicosis. Poult. Sci. 62:2138–2144.
  • Cieglar, A., Fennell, D. L., Mintzlaff, H. J. Leistner, L. 1972. Ochratoxin synthesis by Penicillium species. Die Naturwissenshaften 59:365–366.
  • Delhanty, J. J. Solomon, J. B. 1966. The nature of antibodies to goat erythrocytes in the developing chicken. Immunology 11:103–113.
  • Dwivedi, P., Burns, R. B. 1984. Effect of ochratoxin A on immunoglobulins in broiler chicks. Res. Vet. Sci. 36:117–121.
  • Dwivedi, P. Burns, R. B. 1985. Immunosuppressive effects of ochratoxin A in young turkeys. Avian Pathol. 14:213–225.
  • Elaroussi, M. A., Mohamed, F. R., El Barkouky, E. M., Atta, A. M., Abdou, A. M. Hatab M. H. 2006. Experimental ochratoxicosis in broiler chickens. Avian Pathol. 35:263–269.
  • Elkady, F. A. 1993. Effect of Ochratoxins on the Immune System of Poultry. M.Sc. Thesis, Faculty of Veterinary Medicine, Cairo University.
  • Gore AB, Qureshi MA. 1997. Enhancement of humoral and cellular immunity by vitamin E after embryonic exposure. Poult. Sci. 76:984–991.
  • Hassan, Z. U., Khan, M. Z., Khan, A. Javed, I. 2010. Pathological responses of White Leghorn breeder hens kept on Ochratoxin A contaminated feed. Pak. Vet. J. 30:118–123.
  • Hassan, Z. U., Khan, M. Z., Khan, A., Javed, I., Sadique, U. Hameed, M. R. 2012. Effect of Ochratoxin A (OTA)-contaminated feed on several health and economic parameters in white leghorn cockerels. Pak. Vet. J. 32:35–40.
  • Hesseltine, C. W., Vandegraft, E. E., Fennell, D. I., Smith, M. L. Shotwell, O. L. 1972. Aspergilli as ochratoxin producers. Mycologia 64:539–550.
  • Hoehler, D. Marquardt, R. R. 1996. Influence of vitamins E and C on the toxic effects of ochratoxin A and T-2 toxin in chicks. Poult. Sci. 75:1508–1515.
  • Horvath, M. E., Cabello, R. G., Blazovics, A., Looij, M. V. D., Barta, I., Muzes, G., Gergely, P. Feher, J. 2001. Effect of silibinin and Vitamin E on restoration of cellular immune response after partial hepatectomy. J. Ethnopharmacol. 77:227–232.
  • Hossain, S. M., Barreto, S. L., Bertechini, A. G., Rios, A. M. Silva, C. G.1998. Influence of dietary Vitamin E level on egg production of broiler breeders, and on the growth and immune response of progeny in comparison with the progeny from eggs injected with Vitamin E. Anim. Feed Sci. Tech. 73:307–317.
  • Huff, W. E. wyatt, R. D. Tucker, T. L. and Hamilton, P. B. 1974. Ochratoxicosis in broiler chickens. Poult. Sci. 53:1585–1591.
  • Juvekar, A. R., Hule, A. K., Sakat, S. S. Chaughule, V. A. 2009. In vitro and in vivo evaluation of immunomodulatory activity of methanol extract of Momordica charantia fruits. Drug Invention Today 1:89–94.
  • Khan, W. A., Khan, M. Z., Khan, A. Hussain, I. 2010. Pathological effects of aflatoxin and their amelioration by Vitamin E in White Leghorn layers. Pak. Vet. J. 30:155–162.
  • Li, Y. C., Ledoux, D. R., Bermudez, A. J., Fritsche, K. L. Rottinghaus, G. E. 1999. Effects of fumonisin B1 on selected immune responses in broiler chicks. Poult. Sci. 78:1275–1282.
  • Meeran, S. M., Katiyar, S., Elmets, C. A. Katiyar, S. K. 2006. Silymarin inhibits UV radiation-induced immunosuppression through augmentation of interleukin-12 in mice. Mol. Cancer Ther. 5:1660–1668.
  • Meydani, M. 1995. Vitamin E. Lancet 345:170–175.
  • Muller, G. Kielstein, P. Kohler, H. Berndt, A. and Rosner, H.. 1995. Studies of the influence of ochratoxin A on immune and defence reactions in mouse model. Mycoses 38:85–91.
  • O’Brien, E. Dietrich, D. R. 2005. Ochratoxin A: the continuing enigma. Crit. Rev. Toxicol. 35:33–60.
  • Peckham, J. C., Doupnik, B. Jr Jones, O. H. Jr. 1971. Acute toxicity of ochratoxins A and B in chicks. Appl. Microbiol. 21:492–494.
  • Politis, I., Fegeros, K., Nitsch, S., Schatzmayr, G. Kantas, D. 2005. Use of Trichosporon mycotoxinivorans to suppress the effects of ochratoxicosis on the immune system of broiler chicks. Br. Poult. Sci. 46:58–65.
  • Qureshi, Z. I., Siddiq, M., Lodhi, L. A., Muhammad, G. Jamil, H. 2010. Effect of Vitamin E-selenium administration during late gestation on productive and reproductive performance in dairy buffaloes and on growth performance of their calves. Pak. Vet. J. 30:83–86.
  • Santin, E., Paulillo, A. C., Maiorka, P. C., Alessi, A. C., Krabbe, E. L. Maiorka, A. 2002. The effects of ochratoxin/aluminosilicate interaction on the tissues and humoral immune response of broilers. Avian Pathol. 31:73–79.
  • Sarker, N., Tsudzuki, M., Nishibori, M., Yasue, H. Yamamoto, Y. 2000. Cell-mediated and humoral immunity and phagocytic ability in chicken Lines divergently selected for serum immunoglobulin M and G levels. Poult. Sci. 79:1705–1709.
  • Schlosberg, A., Elkin, N., Malkinson, M., Orgad, U., Hanji, V., Bogin, E., Weisman, Y., Meroz, M. Bock, R. 1997. Severe hepatopathy in geese and broilers associated with ochratoxin in their feed. Mycopathologia 138:71–76.
  • Shinwari, M. B., Shinwari, M. I. and Shah, M. 2007. Medicinal plants of Margalla hills national park Islamabad. Higher Education Commission Islamabad,Pakistan.
  • Singh, G. S., Chauhan, H. V., Jha, G. J. Singh, K. K. 1990. Immunosuppression due to chronic ochratoxicosis in broiler chicks. J. Comp. Pathol. 103:399–410.
  • Stoev, S. D., Anguelov, G., Ivanov, I. Pavlov, D. 2000. Influence of ochratoxin A and an extract of artichoke on the vaccinal immunity and health in broiler chicks. Exp. Toxicol. Pathol. 52:43–55.
  • Stoev, S. D., Djuvinov, D., Mirtcheva, T., Pavlov, D. Mantle, P. 2002. Studies on some feed additives giving partial protection against ochratoxin A toxicity in chicks. Toxicol. Lett. 135:33–50.
  • Tedesco, D., Steidler, S., Galletti, S., Tameni, M., Sonzogni, O. Ravarotto, L. 2004. Efficacy of silymarin-phospholipid complex in reducing the toxicity of aflatoxin B1 in broiler chicks. Poult. Sci. 83:1839–1843.
  • Trenk, H. L., Butz, M. E. Chu, F. S. 1971. Production of ochratoxins in different cereal products by Aspergillus ochraceus. Appl. Microbiol. 21:1032–1035.
  • ul-Hassan, Z., Khan, M. Z., Khan, A., Javed, I. Saleemi, M. K. 2011a. Immunological status of the progeny of breeder hens kept on Ochratoxin A (OTA)-contaminated feed. J. Immunotoxicol. 8:122–130.
  • ul-Hassan, Z., Khan, M. Z., Saleemi, M. K., Khan, A., Javed, I. Hussain, A. 2011b. Immunological status of White Leghorn chicks hatched from eggs inoculated with Ochratoxin A (OTA). J. Immunotoxicol. 8:204–209.
  • Verma, J., Johri, T. S., Swain, B. K. Ameena, S. 2004. Effect of graded levels of aflatoxin, ochratoxin and their combinations on the performance and immune response of broilers. Br. Poult. Sci. 45:512–518.
  • Wang, G. H., Xue, C. Y., Chen, F., Ma, Y. L., Zhang, X. B., Bi, Y. Z. Cao, Y. C. 2009. Effects of combinations of ochratoxin A and T-2 toxin on immune function of yellow-f,eathered broiler chickens. Poult. Sci. 88:504–510.
  • Wilasrusmee, C., Kittur, S., Shah, G., Siddiqui, J., Bruch, D., Wilasrusmee, S., and .Kittur, D.S. 2002. Immunostimulato,ry effect of Silybum Marianum (milk thistle) extract. Med. Sci. Monit. 8:BR439–BR443.
  • Wilasrusmee, C., Kittur, S., Siddiqui, J., Bruch, D., Wilasrusmee, S. Kittur, D.S. 2002b. In vitro immunomodulatory effects of ten commonly used herbs on murine lymphocytes. J. Alt. Compl. Med. 8:467–475.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.