570
Views
3
CrossRef citations to date
0
Altmetric
Clinical Toxicology Teaching Case

Management of diethylene glycol ingestion

&
Pages 525-527 | Received 14 Mar 2012, Accepted 02 May 2012, Published online: 14 Jun 2012

References

  • Besenhofer LM, McLaren MC, Latimer B, . Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol. Toxicol Sci 2011; 123:374–383.
  • Schep LJ, Slaughter RJ, Temple WA, Beasley DM. Diethylene glycol poisoning. Clin Toxicol (Phila) 2009; 47:525–535.
  • Kraut JA, Kurtz I. Toxic alcohol ingestions: clinical features, diagnosis, and management. Clin J Am Soc Nephrol 2008; 3:208–225 (Epub 2007 Nov 28).
  • Brent J. Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings. Clin Toxicol (Phila) 2010; 48:401–406.
  • Besenhofer LM, Adegboyega PA, Bartels M, Filary MJ, Perala AW, McLaren MC, McMartin KE. Inhibition of metabolism of diethylene glycol prevents target organ toxicity in rats. Toxicol Sci 2010; 117: 25–35 (Epub 2010 Jun 7).
  • Brophy PD, Tenenbein M, Gardner J, Bunchman TE, Smoyer WE. Childhood diethylene glycol poisoning treated with alcohol dehydrogenase inhibitor fomepizole and hemodialysis. Am J Kidney Dis 2000; 35:958–962.
  • Borron SW, Baud FJ, Garnier R. Intravenous 4-methylpyrazole as an antidote for diethylene glycol and triethylene glycol poisoning: a case report. Vet Hum Toxicol 1997; 39:26–28.
  • Casas R, Ruck B, Marcus S. A case of diethylene glycol ingestion treated successfully with blocking therapy and dialysis. Clin Toxicol 2005; 43:741.
  • Marraffia JM, Holland MG, Stork CM, . Multi-organ effects after intentional diethylene glycol ingestion. Clin Toxicol 2005; 43:690.
  • Landry GM, Martin S, McMartin, KE. Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro. Toxicol Sci 2011; 124:35–44.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.