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Clinical Toxicology Volume 51, 2013 - Issue 3
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A case of 25I-NBOMe (25-I) intoxication: a new potent 5-HT2A agonist designer drug

S. Rutherfoord RoseDepartment of Emergency MedicineCorrespondence[email protected]
,
Justin L. PoklisDepartment of Pharmacology and Toxicology
&
Alphonse PoklisDepartment of Pharmacology and Toxicology;Department of Pathology, Virginia Commonwealth University, Richmond, VA, USA
Pages 174-177 | Received 27 Nov 2012, Accepted 28 Jan 2013, Published online: 11 Mar 2013

References

  • Gibbons S. “Legal Highs” – novel and emerging psychoactive drugs: a chemical overview for the toxicologist. Clin Toxicol 2012; 50:15–24.
  • Prosser JM, Nelson LS. The toxicology of bath salts: a review of synthetic cathinones. J Med Toxicol 2012; 8:33–42.
  • Fass JA, Fass AD, Garcia AS. Synthetic cathinones (bath salts): legal status and patterns of abuse. Ann Pharmacother 2012; 46:436–441.
  • Spiller HA, Ryan ML, Weston RG, Jansen J. Clinical experience with and analytical confirmation of “bath salts” and “legal highs” (synthetic cathinones) in the United States. Clin Toxicol 2011; 49:499–505.
  • Murphy CM, Dulaney AR, Beuhler MC, Kacinko S. “Bath Salts” and “Plant Food” products: the experience of one regional US poison center. J Med Toxicol 2012 online.
  • Zuba D, Sekula K. Identification and characterization of 2,5-dimethoxy-3,4-dimethyl-B-phenethylamine (2C-G) – a new designer drug. Drug Test Anal 2012; (www.drugtestinganalysis.com) doi:10.1002/dta.1396.
  • Zuba D, Sekula K, Buczek A. 25C-NBOMe – new potent hallucinogenic substance identified on the drug market.(in press) Forensic Sci Int 2012; http://dx.doi.org/10.1016/j.forsciint.2012.08.027.
  • Nichols DE, Frescasa SP, Chemela BR, Rehderb KS, Zhongb D, Lewin AH. High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): A high-affinity 5-HT2A receptor-selective agonist radioligand. Bioorg Med Chem 2008; 16:6116–6123.
  • Braden MR, Parrish JC, Naylor JC, Nichols DE. Molecular interaction of serotonin 5-HT2A receptor residues Phe339(651) and Phe340(652) with superpotent N-benzyl phenethylamine agonists. Mol Pharmacol 2006; 70:1956–1964.
  • Aghaajanian GK, Marek GJ. Serotonin and hallucinogens. Neuropyschopharmacol 1999; 21:16S–23S.
  • Drees J, Stone JA, Wu AHB. Morbidity involving the hallucinogenic designer amines MDA and 2C-I. J Forensic Sci 2009; 54: 1485–1487.
  • Kelly A, Eisenga B, Riley B, Judge B. Case series of 25I-NBOMe exposures with laboratory confirmation. [abstract] Clin Toxicol 2012; 50:702.
  • Rose SR, Cumpston KL, Stromberg PE, Wills BK. Severe poisoning following self-reported use of 25-I, a novel substituted amphetamine. [abstract] Clin Toxicol 2012; 50:707–708.
  • Jackson L. Commonwealth of Virginia Department of Forensic Science, Scientific Advisory Committee Open Meeting, October 9, 2012
  • Hogue C. US criminalizes designer drugs. Chem Eng News 2012; 90:28–29.

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