Difficulty creating an Anticholinergic rat model with atropine

Jared BlumDepartment of Emergency Medicine, The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USACorrespondence[email protected]

Stephanie CarreiroDepartment of Emergency Medicine, The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA

Jason HackDepartment of Emergency Medicine, The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA;Division of Medical Toxicology, The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA

References

de Araújo Junior JX, Julien C, Barres C, de Medeiros IA, Ribeiro EA, Lima LM, Barreiro EJ. Cardiovascular effects of a novel synthetic analogue of naturally occurring piperamides. J Cardiovasc Pharmacol 2010; 56:293–299 . doi:10.1097/FJC.0b013e3181ec061e.
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Kaplanski J, Weinhouse E, Martin O. Modification of digoxin induced arrhythmogenicity in adult rats following atropine administration. Res Commun Chem Pathol Pharmacol 1983; 39:173–176.
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Merrick A, Hadley W, Holcslaw T. The effect of large doses of atropine sulfate on heart rate and blood pressure in rats. Res Commun Chem Pathol Pharmacol 1979; 25:13–22.
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