Advanced search
Publication Cover
Clinical Toxicology Volume 52, 2014 - Issue 5
Submit an article Journal homepage
543
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Evaluation of dexmedetomidine therapy for sedation in patients with toxicological events at an academic medical center

P. L. MohornDepartment of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, SC, USA
,
J. P. VakkalankaDivision of Medical Toxicology, Department of Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USA
,
W. RushtonDivision of Medical Toxicology, Department of Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USA
,
L. HardisonDivision of Medical Toxicology, Department of Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USA
,
A. WoloszynDepartment of Pharmacy Services, University of Virginia Health System, Charlottesville, VA, USA
,
C. HolstegeDivision of Medical Toxicology, Department of Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USA
&
S. M. CorbettDepartment of Pharmacy Services, University of Virginia Health System, Charlottesville, VA, USACorrespondence[email protected]
 show all
Pages 525-530 | Received 30 Dec 2013, Accepted 04 Apr 2014, Published online: 05 May 2014

References

  • Hoy SM, Keating GM. Dexmedetomidine: a review of its use for sedation in mechanically ventilated patients in an intensive care setting and for procedural sedation. Drugs 2011; 71:1481–1501.
  • Muzyk AJ, Fowler JA, Norwood DK, Chilipko A. Role of α2- agonists in the treatment of acute alcohol withdrawal. Ann Pharmacother 2011; 45:649–657.
  • Panharipande PP, Pun BT, Herr DL, Maze M, Girard TD, Miller RR, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007; 298:2644–2653.
  • Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA 2009; 301: 489–499.
  • DeMuro JP, Botros DG, Wirkowski E, Hanna AF. Use of dexmedetomidine for the treatment of alcohol withdrawal syndrome in critically ill patients: a retrospective case series. J Anesth 2012; 26:601–605.
  • Darrouj J, Puri N, Prince E, Lomonaco A, Spevetz A, Gerber DR. Dexmedetomidine infusion as adjunctive therapy to benzodiazepines for acute alcohol withdrawal. Ann Pharmacother 2008; 42: 1703–1705.
  • Oschman A, McCabe T, Kuhn RJ. Dexmedetomidine for opioid and benzodiazepine withdrawal in pediatric patients. Am J Health Syst Pharm 2011; 68:1233–1238.
  • Bagdure DN, Bhoite GR, Reiter PD, Dobyns EL. Dexmedetomidine in a child with methylphenidate intoxication. Indian J Pediatr 2013; 80:343–344.
  • Product Information. Precedex (dexmedetomidine). Lake Forest, IL: Hospira; June 2004.
  • Jakob SM, Ruokonen E, Grounds RM, Sarapohja T, Garratt C, Pocock SJ, et al. Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA 2012; 307:1151–1160.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.