H₂S induced coma and cardiogenic shock in the rat: Effects of phenothiazinium chromophores

References

• Sonobe T, Haouzi P. Sulfide Intoxication-Induced Circulatory Failure is Mediated by a Depression in Cardiac Contractility. Cardiovasc Toxicol 2015.
   PubMedGoogle Scholar
• Haouzi P, Chenuel B, Sonobe T. High-dose hydroxocobalamin administered after H2S exposure counteracts sulfide-poisoning-induced cardiac depression in sheep. Clin Toxicol (Phila) 2015; 53:28–36.
   PubMed Web of Science ®Google Scholar
• Baldelli RJ, Green FH, Auer RN. Sulfide toxicity: mechanical ventilation and hypotension determine survival rate and brain necrosis. J Appl Physiol (1985) 1993; 75:1348–1353.
   PubMed Web of Science ®Google Scholar
• Sun YG, Cao YX, Wang WW, Ma SF, Yao T, Zhu YC. Hydrogen sulphide is an inhibitor of L-type calcium channels and mechanical contraction in rat cardiomyocytes. Cardiovasc Res 2008; 79:632–641.
   PubMed Web of Science ®Google Scholar
• Zhang R, Sun Y, Tsai H, Tang C, Jin H, Du J. Hydrogen sulfide inhibits L-type calcium currents depending upon the protein sulfhydryl state in rat cardiomyocytes. PLoS One 2012; 7:e37073.
   PubMed Web of Science ®Google Scholar
• Cooper CE, Brown GC. The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance. J Bioenerg Biomembr 2008; 40:533–539.
   PubMed Web of Science ®Google Scholar
• Khan AA, Schuler MM, Prior MG, Yong S, Coppock RW, Florence LZ, Lillie LE. Effects of hydrogen sulfide exposure on lung mitochondrial respiratory chain enzymes in rats. Toxicol Appl Pharmacol 1990; 103:482–490.
   PubMed Web of Science ®Google Scholar
• Rastaldo R, Pagliaro P, Cappello S, Penna C, Mancardi D, Westerhof N, Losano G. Nitric oxide and cardiac function. Life Sci 2007; 81:779–793.
   PubMed Web of Science ®Google Scholar
• Brady AJ, Poole-Wilson PA, Harding SE, Warren JB. Nitric oxide production within cardiac myocytes reduces their contractility in endotoxemia. Am J Physiol 1992; 263:H1963–1966.
   PubMed Web of Science ®Google Scholar
• Coletta C, Papapetropoulos A, Erdelyi K, Olah G, Modis K, Panopoulos P, Asimakopoulou A, Gero D, Sharina I, Martin E, Szabo C. Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation. Proc Natl Acad Sci U S A 2012; 109:9161–9166.
   PubMed Web of Science ®Google Scholar
• Altaany Z, Yang G, Wang R. Crosstalk between hydrogen sulfide and nitric oxide in endothelial cells. J Cell Mol Med 2013; 17:879–888.
   PubMed Web of Science ®Google Scholar
• Wainwright M, Amaral L. The phenothiazinium chromophore and the evolution of antimalarial drugs. Trop Med Int Health 2005; 10: 501–511.
   PubMed Web of Science ®Google Scholar
• Warth A, Goeppert B, Bopp C, Schirmacher P, Flechtenmacher C, Burhenne J. Turquoise to dark green organs at autopsy. Virchows Arch 2009; 454:341–344.
   PubMed Web of Science ®Google Scholar
• Schirmer RH, Adler H, Pickhardt M, Mandelkow E. “Lest we forget you - methylene blue ... .” Neurobiol Aging 2011; 32:2325.e7–16.
   PubMed Web of Science ®Google Scholar
• Zhang X, Rojas JC, Gonzalez-Lima F. Methylene blue prevents neurodegeneration caused by rotenone in the retina. Neurotox Res 2006; 9:47–57.
   PubMed Web of Science ®Google Scholar
• Scott A, Hunter FE, Jr. Support of thyroxine-induced swelling of liver mitochondria by generation of high energy intermediates at any one of three sites in electron transport. J Biol Chem 1966; 241:1060–1066.
   PubMed Web of Science ®Google Scholar
• Lindahl PE, Oberg KE. The effect of rotenone on respiration and its point of attack. Exp Cell Res 1961; 23:228–237.
   PubMed Web of Science ®Google Scholar
• Callaway NL, Riha PD, Bruchey AK, Munshi Z, Gonzalez-Lima F. Methylene blue improves brain oxidative metabolism and memory retention in rats. Pharmacol Biochem Behav 2004; 77:175–181.
   PubMed Web of Science ®Google Scholar
• Bouillaud F, Blachier F. Mitochondria and sulfide: a very old story of poisoning, feeding, and signaling? Antioxid Redox Signal 2011; 15:379–391.
   PubMed Web of Science ®Google Scholar
• Buckler KJ. Effects of exogenous hydrogen sulphide on calcium signalling, background (TASK) K channel activity and mitochondrial function in chemoreceptor cells. Pflugers Arch 2012; 463:743–754.
   PubMed Web of Science ®Google Scholar
• Riha PD, Rojas JC, Gonzalez-Lima F. Beneficial network effects of methylene blue in an amnestic model. Neuroimage 2011; 54: 2623–2634.
   PubMed Web of Science ®Google Scholar
• Callaway NL, Riha PD, Wrubel KM, McCollum D, Gonzalez-Lima F. Methylene blue restores spatial memory retention impaired by an inhibitor of cytochrome oxidase in rats. Neurosci Lett 2002; 332: 83–86.
   PubMed Web of Science ®Google Scholar
• Sahlin B. The antagonism between methylene blue and cyan potassium. Skandinavisches Archiv Fur Physiologie 1926; 47:284–291.
   Google Scholar
• Eddy NB. Antagonism between Methylene Blue and Sodium Cyanide. J Pharmacol & Exper Therap 1930; 39:271.
   Google Scholar
• Martijn C, Wiklund L. Effect of methylene blue on the genomic response to reperfusion injury induced by cardiac arrest and cardiopulmonary resuscitation in porcine brain. BMC Med Genomics 2010; 3:27.
   PubMedGoogle Scholar
• Miclescu A, Basu S, Wiklund L. Methylene blue added to a hypertonic-hyperoncotic solution increases short-term survival in experimental cardiac arrest. Crit Care Med 2006; 34:2806–2813.
   PubMed Web of Science ®Google Scholar
• Miclescu A, Basu S, Wiklund L. Cardio-cerebral and metabolic effects of methylene blue in hypertonic sodium lactate during experimental cardiopulmonary resuscitation. Resuscitation 2007; 75:88–97.
   PubMed Web of Science ®Google Scholar
• Wiklund L, Basu S, Miclescu A, Wiklund P, Ronquist G, Sharma HS. Neuro- and cardioprotective effects of blockade of nitric oxide action by administration of methylene blue. Ann N Y Acad Sci 2007; 1122:231–244.
   PubMed Web of Science ®Google Scholar
• Wiklund L, Zoerner F, Semenas E, Miclescu A, Basu S, Sharma HS. Improved neuroprotective effect of methylene blue with hypothermia after porcine cardiac arrest. Acta Anaesthesiol Scand 2013; 57: 1073–1082.
   PubMed Web of Science ®Google Scholar
• Ginimuge PR, Jyothi SD. Methylene blue: revisited. J Anaesthesiol Clin Pharmacol 2010; 26:517–520.
   PubMedGoogle Scholar
• Martin W, Villani GM, Jothianandan D, Furchgott RF. Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J Pharmacol Exp Ther 1985; 232:708–716.
   PubMed Web of Science ®Google Scholar
• Olgart C, Wiklund NP, Gustafsson LE. Blockade of nitric oxide-evoked smooth muscle contractions by an inhibitor of guanylyl cyclase. Neuroreport 1997; 8:3355–3358.
   PubMed Web of Science ®Google Scholar
• Levin RL, Degrange MA, Bruno GF, Del Mazo CD, Taborda DJ, Griotti JJ, Boullon FJ. Methylene blue reduces mortality and morbidity in vasoplegic patients after cardiac surgery. Ann Thorac Surg 2004; 77:496–499.
   PubMed Web of Science ®Google Scholar
• Gachot B, Bedos JP, Veber B, Wolff M, Regnier B. Short-term effects of methylene blue on hemodynamics and gas exchange in humans with septic shock. Intensive Care Med 1995; 21:1027–1031.
   PubMed Web of Science ®Google Scholar
• Grayling M, Deakin CD. Methylene blue during cardiopulmonary bypass to treat refractory hypotension in septic endocarditis. J Thorac Cardiovasc Surg 2003; 125:426–427.
   PubMed Web of Science ®Google Scholar
• Kofidis T, Struber M, Wilhelmi M, Anssar M, Simon A, Harringer W, Haverich A. Reversal of severe vasoplegia with single-dose methylene blue after heart transplantation. J Thorac Cardiovasc Surg 2001; 122:823–824.
   PubMed Web of Science ®Google Scholar
• Menardi AC, Capellini VK, Celotto AC, Albuquerque AA, Viaro F, Vicente WV, Rodrigues AJ, Evora PR. Methylene blue administration in the compound 48/80-induced anaphylactic shock: hemodynamic study in pigs. Acta Cir Bras 2011; 26:481–489.
   PubMed Web of Science ®Google Scholar
• Evora PR, Ribeiro PJ, de Andrade JC. Methylene blue administration in SIRS after cardiac operations. Ann Thorac Surg 1997; 63: 1212–1213.
   PubMed Web of Science ®Google Scholar
• Egi M, Bellomo R, Langenberg C, Haase M, Haase A, Doolan L, Matalanis G, Seevenayagam S, Buxton B. Selecting a vasopressor drug for vasoplegic shock after adult cardiac surgery: a systematic literature review. Ann Thorac Surg 2007; 83:715–723.
   PubMed Web of Science ®Google Scholar
• Leyh RG, Kofidis T, Struber M, Fischer S, Knobloch K, Wachsmann B, Hagl C, Simon AR, Haverich A. Methylene blue: the drug of choice for catecholamine-refractory vasoplegia after cardiopulmonary bypass? J Thorac Cardiovasc Surg 2003; 125:1426–1431.
   PubMed Web of Science ®Google Scholar
• Donati A, Conti G, Loggi S, Munch C, Coltrinari R, Pelaia P, Pietropaoli P, Preiser JC. Does methylene blue administration to septic shock patients affect vascular permeability and blood volume? Crit Care Med 2002; 30:2271–2277.
   PubMed Web of Science ®Google Scholar
• Preiser JC, Lejeune P, Roman A, Carlier E, De Backer D, Leeman M, Kahn RJ, Vincent JL. Methylene blue administration in septic shock: a clinical trial. Crit Care Med 1995; 23:259–264.
   PubMed Web of Science ®Google Scholar
• Paciullo CA, McMahon Horner D, Hatton KW, Flynn JD. Methylene blue for the treatment of septic shock. Pharmacotherapy 2010; 30:702–715.
   PubMed Web of Science ®Google Scholar
• Ali MY, Ping CY, Mok YY, Ling L, Whiteman M, Bhatia M, Moore PK. Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide? Br J Pharmacol 2006; 149:625–634.
   PubMed Web of Science ®Google Scholar
• Tupper DE, Wallace RB. Utility of the neurological examination in rats. Acta Neurobiol Exp (Wars) 1980; 40:999–1003.
   PubMed Web of Science ®Google Scholar
• Klingerman CM, Trushin N, Prokopczyk B, Haouzi P. H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing. Am J Physiol Regul Integr Comp Physiol 2013; 305:R630–638.
   PubMed Web of Science ®Google Scholar
• Millero FJ. The Thermodynamics and Kinetics of the Hydrogen-Sulfide System in Natural-Waters. Mar Chem 1986; 18:121–147.
   Web of Science ®Google Scholar
• Haouzi P, Sonobe T, Torsell-Tubbs N, Prokopczyk B, Chenuel B, Klingerman CM. In Vivo Interactions Between Cobalt or Ferric Compounds and the Pools of Sulphide in the Blood During and After H2S Poisoning. Toxicol Sci 2014; 141:493–504.
   PubMed Web of Science ®Google Scholar
• Van de Louw A, Haouzi P. Ferric Iron and Cobalt (III) compounds to safely decrease hydrogen sulfide in the body? Antioxid Redox Signal 2013; 19:510–516.
   PubMed Web of Science ®Google Scholar
• Van de Louw A, Haouzi P. Oxygen deficit and H2S in hemorrhagic shock in rats. Crit Care 2012; 16:R178.
   PubMed Web of Science ®Google Scholar
• Siegel LM. A Direct Microdetermination for Sulfide. Anal Biochem 1965; 11:126–132.
   PubMed Web of Science ®Google Scholar
• Wintner EA, Deckwerth TL, Langston W, Bengtsson A, Leviten D, Hill P, Insko MA, Dumpit R, VandenEkart E, Toombs CF, Szabo C. A monobromobimane-based assay to measure the pharmacokinetic profile of reactive sulphide species in blood. Br J Pharmacol 2010; 160:941–957.
   PubMed Web of Science ®Google Scholar
• Yang G, Wu L, Jiang B, Yang W, Qi J, Cao K, Meng Q, Mustafa AK, Mu W, Zhang S, Snyder SH, Wang R. H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science 2008; 322:587–590.
   PubMed Web of Science ®Google Scholar
• Zhao W, Zhang J, Lu Y, Wang R. The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener. EMBO J 2001; 20:6008–6016.
   PubMed Web of Science ®Google Scholar
• Hosoki R, Matsuki N, Kimura H. The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. Biochem Biophys Res Commun 1997; 237:527–531.
   PubMed Web of Science ®Google Scholar
• Munaron L, Avanzato D, Moccia F, Mancardi D. Hydrogen sulfide as a regulator of calcium channels. Cell Calcium 2013; 53:77–84.
   PubMed Web of Science ®Google Scholar
• Carroll JJ, Mather AE. The solubility of hydrogen-sulfide in water from 0°C to 90°C and Pressures to 1-Mpa. Geochimica Et Cosmochimica Acta 1989; 53:1163–1170.
   Web of Science ®Google Scholar
• Almgren T, Dyrssen D, Elgquist B, Johannsson O. Dissociation of hydrogen sulfide in seawater and comparison of pH scales. Mar Chem 1976; 4:289–297.
   Google Scholar
• Warenycia MW, Goodwin LR, Francom DM, Dieken FP, Kombian SB, Reiffenstein RJ. Dithiothreitol liberates non-acid labile sulfide from brain tissue of H2S-poisoned animals. Arch Toxicol 1990; 64: 650–655.
   PubMed Web of Science ®Google Scholar
• Mustafa AK, Gadalla MM, Sen N, Kim S, Mu W, Gazi SK, Barrow RK, Yang G, Wang R, Snyder SH. H2S signals through protein S-sulfhydration. Sci Signal 2009; 2:ra72.
   PubMed Web of Science ®Google Scholar
• De Bruyn WJ, Swartz E, Hu JH, Shorter JA, Davidovits P, Worsnop DR, Zahniser S, Kolb CE. Henry's law solubilities and Setchenow coefficients for biogenic reduced sulfur species obtained from gas-liquid uptake measurements. J Geophys Res 1995; 100: 7245–7251.
   Web of Science ®Google Scholar
• Douabul AA, Riley JP. The solubility of gases in distilled water and seawater - V. Hydrogen sulphide. Deep-Sea Research 1979; 26A: 259–268
   Google Scholar
• Barrett TJ, Anderson GM, Lugowski JT. The solubility of hydrogen sulphide in 0–5 m NaCl solutions at 25–95 C and one atmosphere. Geochimica et Cosmochimica Acta 1988; 52:807–811.
   Web of Science ®Google Scholar
• Lagoutte E, Mimoun S, Andriamihaja M, Chaumontet C, Blachier F, Bouillaud F. Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes. Biochim Biophys Acta 2010; 1797:1500–1511.
   PubMed Web of Science ®Google Scholar
• Whitcraft DD, 3rd, Bailey TD, Hart GB. Hydrogen sulfide poisoning treated with hyperbaric oxygen. J Emerg Med 1985; 3:23–25.
   PubMedGoogle Scholar
• Smilkstein MJ, Bronstein AC, Pickett HM, Rumack BH. Hyperbaric oxygen therapy for severe hydrogen sulfide poisoning. J Emerg Med 1985; 3:27–30.
   PubMedGoogle Scholar
• Smith L, Kruszyna H, Smith RP. The effect of methemoglobin on the inhibition of cytochrome c oxidase by cyanide, sulfide or azide. Biochem Pharmacol 1977; 26:2247–2250.
   PubMed Web of Science ®Google Scholar
• Smith RP, Gosselin RE. On the mechanism of sulfide inactivation by methemoglobin. Toxicol Appl Pharmacol 1966; 8:159–172.
   PubMed Web of Science ®Google Scholar
• Smith RP, Gosselin RE. The influence of methemoglobinemia on the lethality of some toxic anions. Ii. Sulfide. Toxicol Appl Pharmacol 1964; 6:584–592.
   PubMed Web of Science ®Google Scholar
• Truong DH, Mihajlovic A, Gunness P, Hindmarsh W, O’Brien PJ. Prevention of hydrogen sulfide (H2S)-induced mouse lethality and cytotoxicity by hydroxocobalamin (vitamin B(12a)). Toxicology 2007; 242:16–22.
   PubMed Web of Science ®Google Scholar
• Haouzi P, Chenuel B, Sonobe T, Klingerman CM. Are H2S-trapping compounds pertinent to the treatment of sulfide poisoning? Clin Toxicol (Phila) 2014; 52:566.
   PubMed Web of Science ®Google Scholar
• Mayer B, Brunner F, Schmidt K. Inhibition of nitric oxide synthesis by methylene blue. Biochem Pharmacol 1993; 45:367–374.
   PubMed Web of Science ®Google Scholar
• Gruetter CA, Kadowitz PJ, Ignarro LJ. Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite. Can J Physiol Pharmacol 1981; 59:150–156.
   PubMed Web of Science ®Google Scholar
• Flesch M, Kilter H, Cremers B, Lenz O, Sudkamp M, Kuhn-Regnier F, Bohm M. Acute effects of nitric oxide and cyclic GMP on human myocardial contractility. J Pharmacol Exp Ther 1997; 281:1340–1349.
   PubMed Web of Science ®Google Scholar
• Aggarwal N, Kupfer Y, Seneviratne C, Tessler S. Methylene blue reverses recalcitrant shock in beta-blocker and calcium channel blocker overdose. BMJ Case Rep 2013; Jan 18:1–2.
   Google Scholar
• Jang DH, Nelson LS, Hoffman RS. Methylene blue in the treatment of refractory shock from an amlodipine overdose. Ann Emerg Med 2011; 58:565–567.
   PubMed Web of Science ®Google Scholar
• Culo F, Sabolovic D, Somogyi L, Marusic M, Berbiguier N, Galey L. Anti-tumoral and anti-inflammatory effects of biological stains. Agents Actions 1991; 34:424–428.
   PubMedGoogle Scholar
• Petzer A, Harvey BH, Wegener G, Petzer JP. Azure B, a metabolite of methylene blue, is a high-potency, reversible inhibitor of monoamine oxidase. Toxicol Appl Pharmacol 2012; 258:403–409.
   PubMed Web of Science ®Google Scholar
• Almeida AF, Nation PN, Guidotti TL. Mechanism and treatment of sulfide-induced coma: a rat model. Int J Toxicol 2008; 27:287–293.
   PubMed Web of Science ®Google Scholar
• Lopez A, Prior MG, Reiffenstein RJ, Goodwin LR. Peracute toxic effects of inhaled hydrogen sulfide and injected sodium hydrosulfide on the lungs of rats. Fundam Appl Toxicol 1989; 12:367–373.
   PubMedGoogle Scholar
• Lopez A, Prior M, Lillie LE, Gulayets C, Atwal OS. Histologic and ultrastructural alterations in lungs of rats exposed to sub-lethal concentrations of hydrogen sulfide. Vet Pathol 1988; 25:376–384.
   PubMed Web of Science ®Google Scholar
• Cheng X, Pang CC. Pressor and vasoconstrictor effects of methylene blue in endotoxaemic rats. Naunyn Schmiedebergs Arch Pharmacol 1998; 357:648–653.
   PubMed Web of Science ®Google Scholar
• Haggard HW, Greenberg LA. Methylene blue a synergist, not an antidote, for carbon monoxide. Journal of the American Medical Association 1933; 100:2001–2003.
   Google Scholar
• Paya D, Gray GA, Stoclet JC. Effects of methylene blue on blood pressure and reactivity to norepinephrine in endotoxemic rats. J Cardiovasc Pharmacol 1993; 21:926–930.
   PubMed Web of Science ®Google Scholar
• Young JD, Dyar OJ, Xiong L, Zhang J, Gavaghan D. Effect of methylene blue on the vasodilator action of inhaled nitric oxide in hypoxic sheep. Br J Anaesth 1994; 73:511–516.
   PubMed Web of Science ®Google Scholar