Amphetamine Inhibition of Hepatic Drug Metabolism: Evidence for a Competitive Mechanism

Robert T. Louis-Ferdinand Department of Pharmacology & Toxicology, University of Rhode Island Kingston, Rhode Island

George C. Fuller Department of Pharmacology & Toxicology, University of Rhode Island Kingston, Rhode Island

Harbans Lal Department of Pharmacology & Toxicology, University of Rhode Island Kingston, Rhode Island

References

Axelrod J. Studies on sympathomimetic amines II. The bio-transformation and physiological disposition of d-amphetamine and d-methamphetamine. J. Pharmacol. Exptl. Therap. 1954; 110: 315–326
PubMed Web of Science ®Google Scholar
Dingel J. V., Bass A. D. Inhibition of the hepatic metabolism of amphetamine by desipramine. Biochem. Pharmacol. 1969; 18: 1535–1538
PubMed Web of Science ®Google Scholar
Fuller G. C., Olshan A. M., Lal H. The stimulatory effect of phenobarbital on the N-demethylation of p-chloro-N-methylaniline. Life Sci. 1969; 8: 383–387
PubMed Web of Science ®Google Scholar
Schenkman J. B., Frey I., Remmer H., Estabrook R. W. Sex differences in drug metabolism by rat liver microsomes. Mol. Pharmacol. 1967; 3: 516–525
PubMed Web of Science ®Google Scholar
Lal H., Puri S. K., Fuller G. C. Inhibition of hepatic hexobarbital metabolism by dextroamphetamine. Psychopharmacologia (Berl.) 1970; 16: 395–398
PubMedGoogle Scholar
Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951; 193: 265–275
PubMed Web of Science ®Google Scholar
Perel J. M., Black N., Wharton R. N., Malitz S. Inhibition of imipramine metabolism by methylphenidate. Federation Proc. 1969; 28: 418
Google Scholar

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