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Clinical Toxicology Volume 8, 1975 - Issue 1
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Research Article

Alkaloids of Tobacco and Blood Coagulation: Effect of Nicotine on Thrombin and Fibrinogen

Jasbir M. Singh Department of Pharmacology, Xavier University College of Pharmacy, New Orleans, Louisiana; Alcoholism Services Unit, Department of Psychiatry, Charity Hospital of Louisiana, New Orleans, Louisiana; Alcoholism Out Patient Treatment Clinic, 3901 Houma Blvd., Metairie, La., 70002
&
Melbra Diane Singh Department of Pharmacology, Xavier University College of Pharmacy, New Orleans, Louisiana
Pages 43-52 | Published online: 25 Sep 2008

References

  • Singh J. M. Effect of nicotine on blood clotting of albino rats fed atherogenic diet. Arch. Int. Pharmacodyn. 1965; 154: 221
  • Singh J. M., Oester Y. T. Possible effect of nicotine on in vitro human blood coagulation time. Arch. Int. Pharmacodyn. 1964; 148: 237
  • Singh J. M., Oester Y. T. Nicotine antagonism with heparin: Possible mode of action on human blood coagulation. Arch. Int. Pharmacodyn. 1964; 149: 354
  • Singh J. M., Oester Y. T. Effect of nicotine on prothrombin time and its possible mode of action. Arch. Int. Pharmacodyn. 1964; 154: 435
  • Wenzel D. G., Singh J. M., Turner J. A. Chronic effects of orally administered nicotine in cholesterol fed rabbits. Ann. N.Y. Acad. Sci. 1960; 90: 302
  • Wenzel D. G., Singh J. M. Effect of nicotine and epinephrine on in vivo blood coagulation time. J. Pharm. Sci. 1963; 51: 875
  • Wenzel D. G., Turner J. A., Jordan S. W., Singh J. M. Cardiovascular interactions of nicotine, ergonovine, and hyper-cholesterolemia in the rabbits. Circ. Res. 1961; 9: 694
  • Wenzel D. G., Singh J. M. Effect of nicotine and epinephrine on in vivo blood coagulation time. J. Pharm. Sci. 1963; 51: 875
  • Seegers W. H. Prothrombin. Harvard University Press, Cambridge, Mass. 1962

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