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Research Article

Impaired Metabolism of Methylphenobarbital after a Combined Drug Overdose: Treatment by Resin Hemoperfusion

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Pages 187-196 | Published online: 25 Sep 2008

References

  • Butler T. J. Quantitative studies of the metabolic fate of mephobarbital (n-methylphenobarbital). J. Pharmacol. Exp. Ther. 1952; 106: 235
  • Butler T. C., Mahaffee D., Mahaffee C. The role of the liver in the metabolic disposition of mephobarbital. J. Pharmacol. Exp. Ther. 1952; 106: 364
  • Svensmark O., Buchtal F. Accumulation of phenobarbital in man. Epilepsia 1963; 4: 199
  • Kupferberg H. J., Longacre-Shaw J. Mephobarbital and phenobarbital plasma concentrations in epileptic patients treated with mephobarbital. Ther. Drug Monitor 1979; 1: 117
  • Craig C. R., Shideman F. E. Metabolism and anticonvulsant properties of mephobarbital and phenobarbital in rats. J. Pharmacol. Exp. Ther. 1971; 176: 35
  • Arieff A. L., Friedman E. A. Coma following nonnarcotic drug overdosage: Management of 208 adult patients. Am. J. Med. Sci. 1973; 266: 405
  • Gotch F. A. Hemodialysis: Technical and kinetic considerations. The Kidney, B. M. Brenner, F. C. Rector, Jr. Saunders, Philadalphia 1976; 1672
  • Benowitz N. L., Abolin C., Tozer T., Rosenberg J., Rogers W., Pond S., Humphreys M., Schoenfeld P. Evaluation of resin hemoperfusion for ethchlorvynol overdose. Clin. Pharmacol. Ther. 1980; 27: 236
  • Rosenberg J., Benowitz N. L., Pond S. Pharmacokinetics of drug overdose. Clin. Pharmacokinet. 1981; 6: 161
  • Mathew H., Lawson A. A. H. Acute barbiturate poisoning: A review of two years experience. Q. J. Med. 1966; 35: 539–552
  • Eadie M. J., Tyrer J. W. H. Neurological Clinical Pharmacology. ADIS Press, New York 1980; 188
  • Alvin J., McHorse T., Hoyumpa A., Bush M. T., Schenker S. The effect of liver disease in man on the disposition of phenobarbital. J. Pharmacol. Exp. Ther. 1975; 192: 224
  • Martin P. R., Bhushan M. K., Shiteside E. A., Sellers E. M. Intravenous phenobarbital therapy in barbiturate and other hypnosedative withdrawal reactions: A kinetic approach. Clin. Pharmacol. Ther. 1979; 26: 256
  • Hooper W. D., Kunze H. E., Eadie M. J. Pharmacokinetics and bioavailability of methylphenobarbital in man. Ther. Drug. Monitor 1981; 3: 39
  • Pond S., Rosenberg J., Benowitz N., Takki S. Pharmacokinetics of haemoperfusion for drug overdose. Clin. Pharmacokinet. 1979; 4: 329

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