172
Views
19
CrossRef citations to date
0
Altmetric
Original Article

Tacrolimus (FK 506) Overdose: A Report of Five Cases

, &
Pages 395-399 | Published online: 29 Jul 2009

References

  • McCauley J., Fung J., Jain A., Todo S., Starzl T. E. The effects of FK 506 on renal function after liver transplantation. Transplant Proc 1990; 22: 17S–20S
  • Thomson A. W. FK 506: Profile of an important new immunosuppressant. Transplant Rev 1990; 4: 1–13
  • Goto T., Kino T., Hatanaka H., et al. Discovery of FK 506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. Transplant Proc 1987; 19: 4S–8S
  • Fung J., Alessiani M., Abu‐Elmagd K., et al. Adverse effects associated with the use of FK 506. Transplant Proc 1991; 23: 3105–3108
  • Jain A. B., Fung R., Venkataramanan S., Todo S., Alessiani M., Starzl T. E. FK 506 dosage in human organ transplantation. Transplant Proc 1990; 22: 23–24
  • Venkataramanan R., Jain A., Warty V. S., et al. Pharmacokinetics of FK 506 in transplant patients. Transplant Proc 1991; 23: 2736–2740
  • Hooks M. A. Tacrolimus, a new immunosuppressant‐a review of the literature. Ann Pharmacother 1994; 28: 501–511
  • Jusko W. J., Piekoszewski W., Klintmalm G. B., et al. Pharmacokinetics of tacrolimus in liver transplant patients. Clin Pharmacol Ther 1995; 57: 281–290
  • Sattler M., Guengerich F. P., Yun C. H., Christians U., Sewing K. F. Cytochrome P‐450 3A enzymes are responsible for biotransformation of FK 506 and rapamycin in man and rat. Drug Metab Dispos 1992; 20: 753–761
  • Yasuhara M., Hashida T., Toraguchi M., et al. Pharmacokinetics and pharmacodynamics of FK 506 in pediatric patients receiving living‐related donor liver transplantations. Transplant Proc 1995; 27: 1108–1110
  • Assan R., Fredji G., Larger E., Feutren G., Bismuth H. FK 506/fluconazole interaction enhances FK 506 nephrotoxicity. Diabete Metab 1994; 20: 49–52
  • Schwartz M., Holst B., Facklam D., Buell D. FK 506 in liver transplantation: correlation of whole blood levels with efficacy and toxicity. Transplant Proc 1995; 27: 1107
  • Warty V., Zuckerman S., Venkataramanan R., et al. Tacrolimus analysis: a comparison of different methods and matrices. Ther Drug Monit 1995; 17: 159–167
  • Alessiani M., Cillo U., Fung J. J., et al. Adverse effects of FK 506 overdosage after river transplantation. Transplant Proc 1993; 25: 628–634
  • Atkinson P., Joubert G., Barron A., et al. Hypertrophic cardiomyopathy associated with tacrolimus in paediatric transplant patients. Lancet 1995; 345: 894–896
  • Hibi S., Misawa A., Tamai M., et al. Severe rhabdomyolysis associated with tacrolimus. Lancet 1995; 346: 702
  • Dollinger M. M., Plevris J. N., Chauhan A., MacGilchrist A. J., Finlayson M. D., Hayes P. C. Tacrolimus and cardiotoxicity in adult liver transplant recipients. Lancet 1995; 346: 507
  • Fisher A., Schwartz M., Mor E., et al. Gastrointestinal toxicity associated with FK 506 in liver transplant recipients. Transplant Proc 1994; 26: 3106–3107
  • Fisher A., Mor A., Hytiroglou P., et al. FK 506 hepatoxicity in liver allograft recipients. Transplantation 1995; 59: 1631–1632
  • Platz K. P., Mueller A. R., Blumhardt G. Nephrotoxicity following orthotopic liver transplantation. A comparison between cyclosporine and FK 506. Transplantation 1994; 58: 170–178
  • Porayko M. K., Textor S. C., Krom R. A., et al. Nephrotoxic effects of primary immunosuppression with FK 506 and cyclosporine regimens after liver transplantation. Mayo Clin Proc 1994; 69: 105–111
  • Winkler M., Jost U., Ring B., Gubernatis G., Wonigeit K., Pichlmayr R. Association of elevated FK 506 plasma levels with nephrotoxicity in liver‐grafted patients. Transplant Proc 1991; 23: 3153–3155
  • Sumpio B. E., Phan S. Nephrotoxic potential of FK 506. Transplant Proc 1991; 23: 2789–2790
  • Nielson F. T., Leyssac P. P., Kemp E., Starklint H., Dieperink H. Nephrotoxicity of FK 506: a preliminary study on comparative aspects of FK 506 and cyclosporine nephrotoxicity. Transplant Proc 1994; 26: 3104–3105
  • Andoh T. F., Brudmann E. A., Lindsely J., Houghton D. C., Bennett W. M. Functional and structural characteristics of experimental FK 506 nephrotoxicity. Clin Exp Pharmacol Physiol 1995; 22: 646–654
  • Wijdicks E. F., Wiesner R. H., Dahlke L. J., Drom R. A. FK 506‐induced neurotoxicity in liver transplantation. Ann Neurol 1994; 35: 498–501
  • Bronster D. J., Yonover P., Stein J., Scelsa S. N., Miller C. M., Sheiner P. A. Demyelinating sensorimotor polyneuropathy after administration of FK 506. Transplantation 1995; 59: 1066–1068
  • Ayres R. C., Dousset B., Wixon S., Buckels J. A., McMaster P., Mayer A. D. Peripheral neurotoxicity with tacrolimus. Lancet 1994; 343: 862–863

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.