Endothelial cell damage following sulfur mustard exposure in rabbits and its association with the delayed-onset ocular lesions

References

• Papirmeister B, Feister AJ, Robinson SI, Ford RD. (1991). Medical Defense Against Mustard Gas: Toxic Mechanisms and Pharmacological Implications. Boca Raton, FL: CRC Press Inco.
   Google Scholar
• De Courcy TL. A case of mustard gas keratitis under constant observation for a period of twenty years. Br J Ophthalmol 1943;27:54–60.
   PubMedGoogle Scholar
• Blodi FC. Mustard gas keratopathy. Int Ophthalmol Clin 1971;11:1–13.
   PubMedGoogle Scholar
• Geeraets WJ, Abedi S, Blanke RV. Acute corneal injury by mustard gas. South Med J 1977;70:348–350.
   PubMed Web of Science ®Google Scholar
• Dahl H, Gluud B, Vangsted P, Norn M. Eye lesions induced by mustard gas. Acta Ophthalmol Suppl 1985;173:30–31.
   PubMedGoogle Scholar
• Petrali JP, Miskena FJ, Hamilton TA, Finger AV, Janny SJ. Sulfur mustard toxicity of the rabbit eye: an ultrastructural study. J Toxicol Cutan Ocul Toxicol 1997;16:227–237.
   Web of Science ®Google Scholar
• Solberg Y, Alcalay M, Belkin M. Ocular injury by mustard gas. Surv Ophthalmol 1997;41:461–466.
   PubMed Web of Science ®Google Scholar
• Pleyer U, Sherif Z, Baatz H, Hartmann C. Delayed mustard gas keratopathy: clinical findings and confocal microscopy. Am J Ophthalmol 1999;128:506–507.
   PubMed Web of Science ®Google Scholar
• Safarinejad MR, Moosavi SA, Montazeri B. Ocular injuries caused by mustard gas: diagnosis, treatment, and medical defense. Mil Med 2001;166:67–70.
   PubMed Web of Science ®Google Scholar
• Kadar T, Turetz J, Fishbine E, Sahar R, Chapman S, Amir A. Characterization of acute and delayed ocular lesions induced by sulfur mustard in rabbits. Curr Eye Res 2001;22:42–53.
   PubMed Web of Science ®Google Scholar
• Javadi MA, Yazdani S, Sajjadi H, Jadidi K, Karimian F, Einollahi B et al. Chronic and delayed-onset mustard gas keratitis: report of 48 patients and review of literature. Ophthalmology 2005;112:617–625.
   PubMed Web of Science ®Google Scholar
• Ghasemi H, Ghazanfari T, Babaei M, Soroush MR, Yaraee R, Ghassemi-Broumand M et al. Long-term ocular complications of sulfur mustard in the civilian victims of Sardasht, Iran. Cutan Ocul Toxicol 2008;27:317–326.
   PubMed Web of Science ®Google Scholar
• Balali-Mood M, Balali-Mood B. Sulfur mustard poisoning and its complications in Iranian veterans. Iran J Med Sci 2009;34:155–171.
   Google Scholar
• Kadar T, Dachir S, Cohen L, Sahar R, Fishbine E, Cohen M et al. Ocular injuries following sulfur mustard exposure–pathological mechanism and potential therapy. Toxicology 2009;263:59–69.
   PubMed Web of Science ®Google Scholar
• Baradaran-Rafii A, Javadi MA, Rezaei Kanavi M, Eslani M, Jamali H, Karimian F. Limbal stem cell deficiency in chronic and delayed-onset mustard gas keratopathy. Ophthalmology 2010;117:246–252.
   PubMed Web of Science ®Google Scholar
• Kanavi MR, Javadi A, Javadi MA. Chronic and delayed mustard gas keratopathy: a histopathologic and immunohistochemical study. Eur J Ophthalmol 2010;20:839–843.
   PubMed Web of Science ®Google Scholar
• Javadi MA, Jafarinasab MR, Feizi S, Karimian F, Negahban K. Management of mustard gas-induced limbal stem cell deficiency and keratitis. Ophthalmology 2011;118:1272–1281.
   PubMed Web of Science ®Google Scholar
• Kadar T, Horwitz V, Sahar R, Cohen M, Cohen L, Gez R et al. Delayed loss of corneal epithelial stem cells in a chemical injury model associated with limbal stem cell deficiency in rabbits. Curr Eye Res 2011;36:1098–1107.
   PubMed Web of Science ®Google Scholar
• Baradaran-Rafii A, Eslani M, Tseng SC. Sulfur mustard-induced ocular surface disorders. Ocul Surf 2011;9:163–178.
   PubMed Web of Science ®Google Scholar
• McNutt P, Hamilton T, Nelson M, Adkins A, Swartz A, Lawrence R et al. Pathogenesis of acute and delayed corneal lesions after ocular exposure to sulfur mustard vapor. Cornea 2012;31:280–290.
   PubMed Web of Science ®Google Scholar
• Bourne WM, McLaren JW. Clinical responses of the corneal endothelium. Exp Eye Res 2004;78:561–572.
   PubMed Web of Science ®Google Scholar
• Bourne WM. Corneal endothelium–past, present, and future. Eye Contact Lens 2010;36:310–314.
   PubMed Web of Science ®Google Scholar
• Szalai E, Németh G, Berta A, Módis L Jr. Evaluation of the corneal endothelium using noncontact and contact specular microscopy. Cornea 2011;30:567–570.
   PubMed Web of Science ®Google Scholar
• Okumura N, Koizumi N, Ueno M, Sakamoto Y, Takahashi H, Hirata K et al. Enhancement of corneal endothelium wound healing by Rho-associated kinase (ROCK) inhibitor eye drops. Br J Ophthalmol 2011;95:1006–1009.
   PubMed Web of Science ®Google Scholar
• Joyce NC, Meklir B, Joyce SJ, Zieske JD. Cell cycle protein expression and proliferative status in human corneal cells. Invest Ophthalmol Vis Sci 1996;37:645–655.
   PubMed Web of Science ®Google Scholar
• Joyce NC. Proliferative capacity of the corneal endothelium. Prog Retin Eye Res 2003;22:359–389.
   PubMed Web of Science ®Google Scholar
• Hillenaar T, van Cleynenbreugel H, Remeijer L. How normal is the transparent cornea? Effects of aging on corneal morphology. Ophthalmology 2012;119:241–248.
   PubMed Web of Science ®Google Scholar
• Hirsch GR, Pouliquen Y. Corneal changes due to alkali burns. Trans Ophthal Soc UK 1978;98:379–382.
   PubMedGoogle Scholar
• Ozdamar Y, Berker N, Ertugrul G, Gurlevik U, Karakaya J, Ozkan SS. Is there a change of corneal thickness in uveitis with Behçet disease? Cornea 2010;29:1265–1267.
   PubMed Web of Science ®Google Scholar
• Javadi MA, Yazdani S, Kanavi MR, Mohammadpour M, Baradaran-Rafiee A, Jafarinasab MR et al. Long-term outcomes of penetrating keratoplasty in chronic and delayed mustard gas keratitis. Cornea 2007;26:1074–1078.
   PubMed Web of Science ®Google Scholar
• Jafarinasab MR, Zarei-Ghanavati S, Kanavi MR, Karimian F, Soroush MR, Javadi MA. Confocal microscopy in chronic and delayed mustard gas keratopathy. Cornea 2010;29:889–894.
   PubMed Web of Science ®Google Scholar
• Amir A, Turetz J, Chapman S, Fishbeine E, Meshulam J, Sahar R et al. Beneficial effects of topical anti-inflammatory drugs against sulfur mustard-induced ocular lesions in rabbits. J Appl Toxicol 2000;20 Suppl 1:S109–S114.
   PubMedGoogle Scholar
• Amir A, Kadar T, Chapman S, Turetz J, Levy A, Babin M et al. The distribution kinetics of topical 14C-sulfur mustard in rabbit ocular tissues and the effect of acetylcysteine. Cutan Ocular Toxicol 2003;22:201–214.
   Web of Science ®Google Scholar
• Milhorn D, Hamilton T, Nelson M, McNutt P. Progression of ocular sulfur mustard injury: development of a model system. Ann N Y Acad Sci 2010;1194:72–80.
   PubMed Web of Science ®Google Scholar
• Ventura A, Walti R, Bohnke M. Corneal thickness and endothelial density before and after cataract surgery. Br J Ophthalmol 2001;85:18–20.
   PubMed Web of Science ®Google Scholar
• Ehlers N, Hjortdal J. Corneal thickness: measurement and implications. Exp Eye Res 2004;78:543–548.
   PubMed Web of Science ®Google Scholar
• Chung JH, Fagerholm P. Endothelial healing in rabbit corneal alkali wounds. Acta Ophthalmol (Copenh) 1987;65:648–656.
   PubMed Web of Science ®Google Scholar
• Matsuda H, Smelser GK. Endothelial cells in alkali-burned corneas. Ultrastructural alterations. Arch Ophthalmol 1973;89:402–409.
   PubMed Web of Science ®Google Scholar
• Schwartzkopff J, Bredow L, Mahlenbrey S, Boehringer D, Reinhard T. Regeneration of corneal endothelium following complete endothelial cell loss in rat keratoplasty. Mol Vis 2010;16:2368–2375.
   PubMed Web of Science ®Google Scholar
• Kim EK, Kim HB, Chung YT, Kim IC. Endothelial F-actin changes in the alkali burned rabbit cornea. Yonsei Med J 1994;35:484–492.
   PubMedGoogle Scholar
• Leem HS, Lee KJ, Shin KC. Central corneal thickness and corneal endothelial cell changes caused by contact lens use in diabetic patients. Yonsei Med J 2011;52:322–325.
   PubMed Web of Science ®Google Scholar
• Kubota M, Fagerholm P. Corneal alkali burn in the rabbit. Waterbalance, healing and transparency. Acta Ophthalmol (Copenh) 1991;69:635–640.
   PubMed Web of Science ®Google Scholar
• Pillai CT, Dua HS, Azuara-Blanco A, Sarhan AR. Evaluation of corneal endothelium and keratic precipitates by specular microscopy in anterior uveitis. Br J Ophthalmol 2000;84:1367–1371.
   PubMed Web of Science ®Google Scholar