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Review Article

Efficacy and toxicity of antibacterial agents used in wound dressings

Pages 61-67 | Received 03 Jan 2014, Accepted 30 Jan 2014, Published online: 31 Mar 2014

References

  • Shai A, Maibach HI. Wound healing and ulcers of the skin. Berlin: Springer; 2005
  • Suzuki Y, Tanihara M, Nishimura Y, et al. A new drug delivery system with controlled release of antibiotic only in the presence of infection. J Biomed Mater Res 1998;42:112–116
  • Stadelmann WK, Digenis AG, Tobin GR. Impediments to wound healing. Am J Surg 1998;176:39s–47s
  • Fallon MT, Shafer W, Jacob E. Use of cefazolin microspheres to treat localized methicillin-resistant Staphylococcus aureus infections in rats. J Surg Res 1999;86:97–102
  • Jacob E, Cierny G, Fallon MT, et al. Evaluation of biodegradable cefazolin sodium microspheres for the prevention of infection in rabbits with experimental open tibial fractures stabilized with internal-fixation. J Orthopaed Res 1993;11:404–411
  • Zhong W. An introduction to healthcare and medical textiles. Lancaster (PA): DEStech, Inc; 2013
  • McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 1999;12:147–179
  • Prabhu S, Poulose EK. Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects. Int Nano Lett 2012;2:32
  • Lansdown AB, Jensen K, Jensen MQ. Contreet foam and contreet hydrocolloid: an insight into two new silver-containing dressings. J Wound Care 2003;12:205–210
  • Dowsett C. An overview of Acticoat dressing in wound management. Br J Nurs 2003;12:S44–S49
  • Atiyeh BS, Costagliola M, Hayek SN, et al. Effect of silver on burn wound infection control and healing: review of the literature. Burns 2007;33:139–148
  • Poon VKM, Burd A. In vitro cytotoxity of silver: implication for clinical wound care. Burns 2004;30:140–147
  • Wang YZ, Li YX, Yang ST, et al. A convenient route to polyvinyl pyrrolidone/silver nanocomposite by electrospinning. Nanotechnology 2006;17:3304–3307
  • Jin WJ, Lee HK, Jeong EH, et al. Preparation of polymer nanofibers containing silver nanoparticles by using poly (N-vinylpyrrolidone). Macromol Rapid Commun 2005;26:1903–1907
  • Wiegand C, Heinze T, Hipler UC. Comparative in vitro study on cytotoxicity, antimicrobial activity, and binding capacity for pathophysiological factors in chronic wounds of alginate and silver-containing alginate. Wound Repair Regen 2009;17:511–521
  • Rujitanaroj PO, Pimpha N, Supaphol P. Wound-dressing materials with antibacterial activity from electrospun gelatin fiber mats containing silver nanoparticles. Polymer 2008;49:4723–4732
  • Percival SL, Slone W, Linton S, et al. The antimicrobial efficacy of a silver alginate dressing against a broad spectrum of clinically relevant wound isolates. Int Wound J 2011;8:237–243
  • Jain J, Arora S, Rajwade JM, et al. Silver nanoparticles in therapeutics: development of an antimicrobial gel formulation for topical use. Mol Pharmaceut 2009;6:1388–1401
  • Gaisford S, Beezer AE, Bishop AH, et al. An in vitro method for the quantitative determination of the antimicrobial efficacy of silver-containing wound dressings. Int J Pharmaceut 2009;366:111–116
  • Supp AP, Neely AN, Supp DM, et al. Evaluation of cytotoxicity and antimicrobial activity of Acticoat Burn Dressing for management of microbial contamination of cultured skin substitutes grafted to athymic mice. J Burn Care Rehabil 2005;26:238–246
  • Keen JS, Desai PP, Smith CS, et al. Efficacy of hydrosurgical debridement and nanocrystalline silver dressings for infection prevention in type II and III open injuries. Int Wound J 2012;9:7–13
  • Opasanon S, Muangman P, Namviriyachote N. Clinical effectiveness of alginate silver dressing in outpatient management of partial-thickness burns. Int Wound J 2010;7:467–471
  • Beele H, Meuleneire F, Nahuys M, et al. A prospective randomised open label study to evaluate the potential of a new silver alginate/carboxymethylcellulose antimicrobial wound dressing to promote wound healing. Int Wound J 2010;7:262–270
  • Ong SY, Wu J, Moochhala SM, et al. Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties. Biomaterials 2008;29:4323–4332
  • Zou SB, Yoon WY, Han SK, et al. Cytotoxicity of silver dressings on diabetic fibroblasts. Int Wound J 2013;10:306–312
  • Burd A, Kwok CH, Hung SC, et al. A comparative study of the cytotoxicity of silver-based dressings in monolayer cell, tissue explant, and animal models. Wound Repair Regen 2007;15:94–104
  • Rigo C, Ferroni L, Tocco I, et al. Active silver nanoparticles for wound healing. Int J Mol Sci 2013;14:4817–4840
  • Trop M, Novak M, Rodl S, et al. Silver coated dressing acticoat caused raised liver enzymes and argyria-like symptoms in burn patient. J Trauma-Inj Inf Crit Care 2006;60:648–652
  • Choi YS, Lee SB, Hong SR, et al. Studies on gelatin-based sponges. Part III: a comparative study of cross-linked gelatin/alginate, gelatin/hyaluronate and chitosan/hyaluronate sponges and their application as a wound dressing in full-thickness skin defect of rat. J Mater Sci-Mater Med 2001;12:67–73
  • Kim HJ, Choi EY, Oh JS, et al. Possibility of wound dressing using poly(L-leucine)/poly(ethylene glycol)/poly(L-leucine) triblock copolymer. Biomaterials 2000;21:131–141
  • Demling RH, DeSanti MDL. The rate of re-epithelialization across meshed skin grafts is increased with exposure to silver. Burns 2002;28:264–266
  • Jude EB, Apelqvist J, Spraul M, Martini J, the Silver Dressing Study Group. Prospective randomized controlled study of Hydrofiber® dressing containing ionic silver or calcium alginate dressings in non-ischaemic diabetic foot ulcers. Diabet Med 2007;24:280–288
  • Ziegler K, Gorl R, Effing J, et al. Reduced cellular toxicity of a new silver-containing antimicrobial dressing and clinical performance in non-healing wounds. Skin Pharmacol Physiol 2006;19:140–146
  • Eardley WGP, Watts SA, Clasper JC. Extremity trauma, dressings, and wound infection: should every acute limb wound have a silver lining? Int J Lower Extrem Wounds 2012;11:201–212
  • Widgerow AD. Nanocrystalline silver, gelatinases and the clinical implications. Burns 2010;36:965–974
  • McDonough JT. Stedman's concise medical dictionary, 2nd ed. Philadelphia (PA): Williams and Wilkins; 1994
  • Peles Z, Zilberman M. Novel soy protein wound dressings with controlled antibiotic release: mechanical and physical properties. Acta Biomaterialia 2012;8:209–217
  • Elsner JJ, Egozi D, Ullmann Y, et al. Novel biodegradable composite wound dressings with controlled release of antibiotics: results in a guinea pig burn model. Burns 2011;37:896–904
  • Fan L, Cheng C, Qiao YB, et al. GNPs-CS/KGM as hemostatic first aid wound dressing with antibiotic effect: in vitro and in vivo study. PLoS One 2013;8:e66890
  • Xu XL, Zhong W, Zhou SF, et al. Electrospun PEG-PLA nanofibrous membrane for sustained release of hydrophilic antibiotics. J Appl Polym Sci 2010;118:588–595
  • Zhong W, Xing MMQ, Maibach HI. Nanofibrous materials for wound care. Cutan Ocul Toxicol 2010;29:143–152
  • Ranganath SH, Wang CH. Biodegradable microfiber implants delivering paclitaxel for post-surgical chemotherapy against malignant glioma. Biomaterials 2008;29:2996–3003
  • Xu XL, Yang LX, Xu XY, et al. Ultrafine medicated fibers electrospun from W/O emulsions. J Control Rel 2005;108:33–42
  • Li D, Xia YN. Direct fabrication of composite and ceramic hollow nanofibers by electrospinning. Nano Lett 2004;4:933–938
  • He CL, Huang ZM, Han XJ, et al. Coaxial electrospun poly(L-lactic acid) ultrafine fibers for sustained drug delivery. J Macromol Sci B-Physics 2006;45:515–524
  • Zhong W, Xing MMQ, Maibach HI. Nanofibrous materials for wound care. Cutan Ocular Toxicol 2010;29:143–152
  • Elsner JJ, Berdicevsky I, Zilberman M. In vitro microbial inhibition and cellular response to novel biodegradable composite wound dressings with controlled release of antibiotics. Acta Biomaterialia 2011;7:325–336
  • Teo EY, Ong SY, Chong MSK, et al. Polycaprolactone-based fused deposition modeled mesh for delivery of antibacterial agents to infected wounds. Biomaterials 2011;32:279–287
  • Chen J, Zhou B, Li Q, et al. PLLA-PEG-TCH-labeled bioactive molecule nanofibers for tissue engineering. Int J Nanomed 2011;6:2533–2542
  • Pulat M, Kahraman AS, Tan N, et al. Sequential antibiotic and growth factor releasing chitosan-PAAm semi-IPN hydrogel as a novel wound dressing. J Biomater Sci-Polym Ed 2013;24:807–819
  • Unnithan AR, Barakat NAM, Pichiah PBT, et al. Wound-dressing materials with antibacterial activity from electrospun polyurethane-dextran nanofiber mats containing ciprofloxacin HCl. Carbohydrate Polym 2012;90:1786–1793
  • Cunha BA. Antibiotic side effects. Med Clin North Am 2001;85:149–185
  • Westphal JF, Vetter D, Brogard JM. Hepatic side-effects of antibiotics. J Antimicrob Chemother 1994;33:387–401
  • Gleckman RA, Czachor JS. Antibiotic side effects. Semin Respir Crit Care Med 2000;21:53–60
  • Blackburn AS, Avery SV. Genome-wide screening of Saccharomyces cerevisiae to identify genes required for antibiotic insusceptibility of eukaryotes. Antimicrob Agents Chemother 2003;47:676–681
  • Xu H, Chang JM, Chen Y, et al. Asymmetric polyurethane membrane with inflammation-responsive antibacterial activity for potential wound dressing application. J Mater Sci 2013;48:6625–6639
  • Marchesan S, Qu Y, Waddington LJ, et al. Self-assembly of ciprofloxacin and a tripeptide into an antimicrobial nanostructured hydrogel. Biomaterials 2013;34:3678–3687
  • Soscia DA, Raof NA, Xie YB, et al. Antibiotic-loaded PLGA nanofibers for wound healing applications. Adv Eng Mater 2010;12:B83–B88
  • Arias CA, Murray BE. Antibiotic-resistant bugs in the 21st century – a clinical super-challenge. New Engl J Med 2009;360:439–443
  • Ülkür E, Oncul O, Karagoz H, et al. Comparison of silver-coated dressing (Acticoat™), chlorhexidine acetate 0.5% (Bactigrass®), and fusidic acid 2% (Fucidin®) for topical antibacterial effect in methicillin-resistant Staphylococci-contaminated, full-skin thickness rat burn wounds. Burns 2005;31:874–877
  • Lee JH, Chae JD, Kim DG, et al. Comparison of the efficacies of silver-containing dressing materials for treating a full-thickness rodent wound infected by methicillin-resistant Staphylococcus aureus. Korean J Lab Med 2010;30:20–27
  • Wild T, Bruckner M, Payrich M, et al. Eradication of methicillin-resistant Staphylococcus aureus in pressure ulcers comparing a polyhexanide-containing cellulose dressing with polyhexanide swabs in a prospective randomized study. Adv Skin Wound Care 2012;25:17–22
  • Echague CG, Hair PS, Cunnion KM. A comparison of antibacterial activity against methicillin-resistant Staphylococcus aureus and gram-negative organisms for antimicrobial compounds in a unique composite wound dressing. Adv Skin Wound Care 2010;23:406–413
  • Franklin TJ, Snow GA. SpringerLink (Online service), Biochemistry and molecular biology of antimicrobial drug action. New York (NY): Springer; 2005. x, 182p
  • Kim CH, Choi JW, Chun HJ, et al. Synthesis of chitosan derivatives with quaternary ammonium salt and their antibacterial activity. Polymer Bull 1997;38:387–393
  • Lim SH, Hudson SM. Review of chitosan and its derivatives as antimicrobial agents and their uses as textile chemicals. J Macromol Sci-Polym Rev 2003;C43:223–269
  • Ignatova M, Manolova N, Rashkov I. Novel antibacterial fibers of quaternized chitosan and poly(vinyl pyrrolidone) prepared by electrospinning. Eur Polym J 2007;43:1112–1122
  • Gupta D, Haile A. Multifunctional properties of cotton fabric treated with chitosan and carboxymethyl chitosan. Carbohy Polym 2007;69:164–171
  • Ignatova M, Manolova N, Markova N, et al. Electrospun non-woven nanofibrous hybrid mats based on chitosan and PLA for wound-dressing applications. Macromol Biosci 2009;9:102–111
  • Shin Y, Yoo DI, Min K. Antimicrobial finishing of polypropylene nonwoven fabric by treatment with chitosan oligomer. J Appl Polym Sci 1999;74:2911–2916
  • Shin Y, Yoo DI, Jang J. Molecular weight effect on antimicrobial activity of chitosan treated cotton fabrics. J Appl Polym Sci 2001;80:2495–2501
  • Palmeira-de-Oliveira A, Ribeiro MP, Palmeira-de-Oliveira R, et al. Anti-candida activity of a chitosan hydrogel: mechanism of action and cytotoxicity profile. Gynecol Obstetr Investig 2010;70:322–327
  • Huang ME, Khor E, Lim LY. Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharmaceut Res 2004;21:344–353
  • Loretz B, Bernkop-Schnurch A. In vitro cytotoxicity testing of non-thiolated and thiolated chitosan nanoparticles for oral gene delivery. Nanotoxicology 2007;1:139–148
  • Kumar PTS, Lakshmanan VK, Biswas R, et al. Synthesis and biological evaluation of chitin hydrogel/nano ZnO composite bandage as antibacterial wound dressing. J Biomed Nanotechnol 2012;8:891–900
  • Muller G, Koburger T, Kramer A. Interaction of polyhexamethylene biguanide hydrochloride (PHMB) with phosphatidylcholine containing o/w emulsion and consequences for microbicidal efficacy and cytotoxicity. Chem-Biol Interact 2013;201:58–64
  • Muller G, Koburger T, Kramer A, et al. Reduced cytotoxicity of polyhexamethylene biguanide hydrochloride (PHMB) by egg phosphatidylcholine while maintaining antimicrobial efficacy. Chem-Biol Interact 2011;190:171–178
  • Gilbert P, Moore LE. Cationic antiseptics: diversity of action under a common epithet. J Appl Microbiol 2005;99:703–715
  • Cui FY, Li GD, Huang JJ, et al. Development of chitosan-collagen hydrogel incorporated with lysostaphin (CCHL) burn dressing with anti-methicillin-resistant Staphylococcus aureus and promotion wound healing properties. Drug Deliv 2011;18:173–180

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