Differential Effects of Phenolic Antioxidants on the Metabolism of Aflatoxin B₁

References

• Essigmann J.M., Croy R.G., Nadzan A.M., Busby W.F., Jr., Reinhold V.N., Buchi G., Wogan G.N. Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro. Proc. Natl. Acad. Sci. U.S.A. 1977; 74: 1870
   PubMed Web of Science ®Google Scholar
• Raj H.G., Santhanam K., Gupta R.P., Venkita subramanian T.A. Oxidative metabolism of aflatoxin B1: Observations on the formation of epoxide-glutathione conjugate. Chem. Biol. Interact. 1975; 11: 301
   PubMed Web of Science ®Google Scholar
• Degan G.H., Neumann H.G. The major metabolite of aflatoxin B1 in the rat is a glutathione conjugate. Chem. Biol. Interact. 1978; 22: 239
   PubMed Web of Science ®Google Scholar
• Hayes R.B., van Nieuwenhuise J.P., Raatgever Ten J.W., Kate F.J.W. Aflatoxin exposures in the industrial setting: an epidemiological study of mortality. Food Chem. Toxicol. 1984; 22: 39
   PubMed Web of Science ®Google Scholar
• Dvorakova I., Pichova V. Pulmonary interstitial fibrosis with evidence of aflatoxin B1 in lung tissue. J. Toxicol. Environ. Hlth. 1986; 18: 153
   PubMedGoogle Scholar
• Benson A.M., Batzinger R.P., Ou S.Y.L., Bueding E., Cha Y.N., Talalay P. Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo (a) pyrene by dietary antioxidants. Cancer Res. 1978; 38: 4486
   PubMed Web of Science ®Google Scholar
• Benson A.M., Batzinger R.P., Ou S.Y.L., Bueding E., Heine H.S., Talalay P. Elevation of extrahepatic glutathione S-transferase and epoxide hydratase activities by 2(3)-t-butyl-4-hydroxyanisole. Fed. Proc. 1979; 38: 506
   Google Scholar
• Cha Y.N., Martz F., Bueding E. Enhancement of liver microsome epoxide hydratase in rodent by treatment with 2(3) - tert-butyl-4-hydroxyanisole. Cancer Res. 1978; 38: 4496
   PubMed Web of Science ®Google Scholar
• Rahimtula A.D., Jernstrom B., Dock L., Moldeus P. Effects of dietary and in vitro 2(3) -t-butyl-4-hydroxyanisole and other phenols on hepatic enzyme activities in mice. Br. J. Cancer. 1982; 45: 935
   PubMed Web of Science ®Google Scholar
• Cha Y.N., Bueding E. Effect of 2(3)-tert-butyl-4-hydroxy anisole administration on the activities of several hepatic microsomal and cytoplasmic enzymes in mice. Biochem. Pharmacol. 1979; 28: 1917
   PubMed Web of Science ®Google Scholar
• Kensler T.W., Egner P.A., Davidson N.E., Roebuck B.D., Pikul A., Groopman J.D. Modulation of aflatoxin metabolism. Aflatoxin-N7-guanine formation and hepatic tumorigenesis in rats fed ethoxyquin: Role of induction of glutathione S-transferases. Cancer Res. 1986; 46: 3924
   PubMed Web of Science ®Google Scholar
• Mandel H.G., Manson M.M., Judah D.J., Simpson J.L., Green J.A., Forrester L.M., Wolf C.R., Neal G.E. Metabolic basis for the protective effect of the antioxidant ethoxyquin on aflatoxin B1 hepatocarcinogenesis in the rat. Cancer Res. 1987; 47: 5218
   PubMed Web of Science ®Google Scholar
• Jhee E.C., Ho L.L., Lotlikar P.D. Effect of butylated hydroxyanisole pretreatment on in vivo hepatic aflatoxin B1-DNA binding and aflatoxin B1-GSH conjugation in rats. Cancer Res. 1988; 48: 2688
   PubMed Web of Science ®Google Scholar
• Monroe D.H., Holeski C.J., Eaton D.L. Effect of single-dose and repeated dose pretreatment with 2(3) tert-butyl-4-hydroxyanisole (BHA) on the hepatobiliary disposition and covalent binding to DNA of aflatoxin B1 in the rat. Food. Chem. Toxicol. 1986; 24: 1273
   PubMed Web of Science ®Google Scholar
• Netter K.J., Kane R., Elcombe C.R. Significance of induction phenomena. Arch. Toxicol. (Berl.) 1978; 1: 85
   Google Scholar
• King M.M., McCay P.B. Studies on liver microsome of female rats fed purified diets varying in fat content with and without propyl gallate. Food. Cosmet. Toxicol. 1981; 19: 13
   PubMedGoogle Scholar
• Cha Y.N., Heine H.S. Comparative effects of dietary administration of 2(3)-tert-butyl-4-hydroxyanisole and 3,5-di-tert-butyl-4-hydroxy toluene on several hepatic enzyme activities in mice and rats. Cancer Res. 1982; 42: 2609
   PubMed Web of Science ®Google Scholar
• Kahl R., Wulff U. Induction of rat hepatic epoxide hydratase by dietary antioxidants. Toxicol. Appl. pharmacol. 1979; 47: 217
   PubMed Web of Science ®Google Scholar
• Hennings H., Shores R., Wenk M.L., Tarone R., Yuspa S.H. Malignant conversion of mouse skin tumors is increased by tumor initiators and unaffected by tumor promoters. Nature 1983; 304: 67
   PubMed Web of Science ®Google Scholar
• Yang C.S., Strickhart F.S., Woo G.K. Inhibitions of the monooxygenase system by butylated hydroxyanisole and butylated hydroxytoluene. Life Science 1974; 15: 1497
   PubMed Web of Science ®Google Scholar
• Yang C.S., Sydor W.J., Martin M.B., Lewis K.F. Effects of butylated hydroxyanisole on the aryl hydrocarbon hydroxylase of rats and mice. Chem. Biol. Interact 1981; 37: 337
   PubMed Web of Science ®Google Scholar
• Goeger D.E., Shelton D.W., Hendricks J.D., Pereira Cliff, Bailey G. Comparative effect of dietary hydroxyanisole and β-naphthoflavone on aflatoxin B1 metabolism, DNA adduct formation and carcinogenesis in rainbow trout. Carcinogenesis 1988; 9: 1793
   PubMed Web of Science ®Google Scholar
• Lotlikar P.D., Clearfield M.S., Jhee E.C. Effect of butylated hydroxyanisole on in vivo and in vitro hepatic aflatoxin B1-DNA binding in rats. Cancer Lett. 1984; 24: 241
   PubMed Web of Science ®Google Scholar
• Allameh A., Saxena M., Raj H.G. Differential effects of butylated hydroxyanisole on metabolism of aflatoxin B1 in vitro by liver and lung microsomes. Cancer Lett. 1988; 40: 49
   PubMed Web of Science ®Google Scholar
• Kensler T.W., Enger P.A., Trush M.A., Bueding E., Groopman J.D. Modification of aflatoxin B1 binding to DNA in vivo in rats fed phenolic antioxidants, ethoxyquin and dithiothione. Carcinogenesis (Lond.) 1985; 6: 759
   PubMed Web of Science ®Google Scholar
• Chang Y., Bjeldanes L.F. R-Goitrin-and BHA-induced modulation of aflatoxin B1 binding to DNA and biliary excretion of thiol conjugates in rats. Carcinogenesis (Lond.) 1987; 8: 585
   PubMed Web of Science ®Google Scholar
• Fukuyama M.Y., Hsieh D.P.H. Effect of butylated hydroxytoluene pretreatment on the excretion tissue distribution and DNA binding of [14C] aflatoxin B1 in the rat. Food. Chem. Toxicol. 1985; 23: 567
   PubMed Web of Science ®Google Scholar
• Wattenberg L.W. Perspective in Cancer Research. Chemoprevention of Cancer. Cancer Res. 1985; 45: 1
   PubMed Web of Science ®Google Scholar
• Wattenberg L.W. Protective effects of 2(3)-tert-butyl-4-hydroxyanisole on chemical carcinogenesis. Food. Chem. Toxicol. 1986; 24: 1099
   PubMed Web of Science ®Google Scholar
• Williams G.M., Tanaka T., Maeura Y. Dose-related inhibition of aflatoxin B1 induced-hepatocarcinogenesis by the phenolic antioxidants, butylated hydroxyanisole and butylated hydroxytoluene. Carcinogenesis (Lond.) 1986; 7: 1043
   PubMed Web of Science ®Google Scholar