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Research Article

Microsome Mediated Aflatoxin B1-8,9-Epoxide Conjugation to Glutathione in Presence of Purified Hepatic Glutathione S-Transferases from Control and Butylated Hydroxyanisole Pretreated Rats

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Pages 155-164 | Published online: 28 Sep 2008

References

  • Newberne P.M., Butler W.H. Acute and Chronic Effects of Aflatoxin B1 on the Liver of Domestic and Laboratory Animals: A Review. Cancer Res. 1969; 29: 236–250
  • Roebuck B.D., Wogan G.N. Species Comparison of In Vitro Metabolism of Aflatoxin B1. Cancer Res. 1977; 37: 1649–1656
  • Harris C.C., Sun T.T. Commentary: Multifactorial Etiology of Human Cancer. Carcinogenesis (Lond.) 1984; 5: 697–701
  • Wattenberg L.W. Perspectives in Cancer Research. Chemoprevention of Cancer. Cancer Res. 1985; 45: 1–8
  • Wattenberg L.W. Protective Effects of 2(3)-Tert-butyl-4-hydroxyanisole on Chemical Carcinogenesis. Food Chem. Toxicol. 1986; 24: 1099–1102
  • Campbell T.C., Hayes J.R. The Role of Aflatoxin Metabolism in Its Toxic Lesion. Toxicol. Appl. Pharmacol. 1976; 35: 199–222
  • Miller J.A., Miller E.C. Ultimate Chemical Carcinogens as Reactive Mutagenic Electrophiles. Origins of Human Cancer, H.H. Hiatt, J.D. Watson, J.A. Winsten. Cold Springs Harbor. 1977; 605–627
  • Essigmann J.M., Croy R.G., Nadzan A.M., Busby W.F., Jr., Reinhold V.N., Büchi G., Wogan G.N. Structural Identification of the Major DNA Adduct Formed by Aflatoxin B1 In Vitro. Proc. Natl. Acad. Sci., USA 1977; 74: 1870–1874
  • Degen G.H., Neumann H.G. Differences in Aflatoxin B1 Susceptibility of Rat and Mouse are Correlated with the Capability In Vitro to Inactivate Aflatoxin B1 Epoxide. Carcinogenesis (Lond.) 1981; 2: 299–306
  • Neal G.E., Metcalfe S.A., Legg R.F., Judah A.J., Green J.A. Mechanism of the Resistance to Cytotoxicity which Precedes Aflatoxin B1 Hepatocarcinogenesis. Carcinogenesis (Lond.) 1981; 2: 457–461
  • O'Brien K., Moss E., Judah D., Neal G.E. Metabolic Basis of the Species Differences to Aflatoxin B1 Induced Hepatotoxicity. Biochem. Biophys. Res. Commun. 1983; 114: 813–821
  • Lotlikar P.D., Insetta S.M., Lyons P.R., Jhee E.C. Inhibition of Microsome Mediated Binding of Aflatoxin B1 to DNA by Glutathione S-transferase. Cancer Lett. 1980; 9: 143–149
  • Lotlikar P.D., Jhee E.C., Insetta S.M., Clearfield M.S. Modulation of Microsome Mediated Aflatoxin B1 Binding to Exogenous and Endogenous DNA by Cytosolic Glutathione S-Transferase in Rat and Hamster Livers. Carcinogenesis (Lond.) 1984; 5: 269–276
  • Raj H.G., Clearfield M.S., Lotlikar P.D. Comparative Kinetic Studies on Aflatoxin B1-DNA Binding and Aflatoxin B1-Glutathione Conjugation with Rat and Hamster Livers In Vitro. Carcinogenesis (Lond.) 1984; 5: 879–884
  • Cha Y.N., Heine H.S. Comparative Effects of Dietary Administration of 2(3)-Tert-butyl-4-hydroxyanisole and 3,5-Di-butyl-4-hydroxytoluene on Several Hepatic Enzyme Activities in Mice and Rats. Cancer Res. 1982; 42: 2609–2615
  • Benson A.M., Cha Y.N., Bueding E., Heine H.S., Talalay P. Elevation of Extrahepatic Glutathione S-Transferase and Epoxide Hydratase Activities by 2(3)-Tert-butyl-4-hydroxyanisole. Cancer Res. 1979; 39: 2971–2977
  • Lotlikar P.D., Clearfield M.S., Jhee E.C. Effect of Butylated Hydroxyanisole on In Vivo and In Vitro Hepatic Aflatoxin B1-DNA Binding in Rats. Cancer Lett. 1984; 24: 241–250
  • Jhee E.C., Ho L.L., Lotlikar P.D. Effects of Butylated Hydroxyanisole (BHA) Pretreatment on In Vitro Hepatic Aflatoxin B1 (AFB1-SG) Conjugation in Rats. Cancer Res. 1988; 48: 2688–2692
  • Jensson H., Alin P., Mannervik B. Glutathione Transferase Isoenzymes from Rat Liver Cytosol. Methods Enzymol. 1988; 113: 504–507
  • Habig W.H., Jakoby W.B. Assays for Differentiation of Glutathione S-Transferases. Methods Enzymol. 1981; 77: 398–405
  • Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J. Protein Measurement with the Folin Phenol Reagent. J. Biol. Chem. 1951; 193: 265–275
  • Ketterer B., Coles B., Meyer D.J. Role of Glutatione in Detoxication. Env. Health. Perspect. 1983; 49: 59–69
  • Degen G.H., Neumann H.G. The Major Metabolites of Aflatoxin B1 in the Rat is a Glutathione Conjugate. Chem.-Biol. Interactions 1978; 2: 239–255
  • Moss E.J., Judah D.J., Przyblyski M., Neal G.E. Some Mass-Spectral and N.M.R. Analytical Studies of a Glutathione Conjugate of Aflatoxin B1. Biochem. J. 1983; 210: 227–233
  • Coles B., Meyer D.J., Ketterer B., Stanton C.A., Carter C. Studies on the Detoxication of Microsomally Activated AFB1 by Glutathione and Glutathione Transferase In Vitro. Carcinogenesis (Lond.) 1985; 6: 693–697
  • Neal G.E., Green J.A. The Requirement for Glutathione S-Transferase in the Conjugation of Activated AFB1 During Aflatoxin B1 Carcinogenesis in the Rat. Chem. Biol. Interactions 1983; 45: 259–275
  • Jensen D., McKay R.L. 1989, Manuscript in preparation
  • Smith M.T., Evans C.G., Doane-Setzer P., Castro V.M., Tahir M.K., Mannervik B. Denitrosation of 1,3-Bis(2-Chloroethyl)-1-nitrosourea by Class Mμ Glutathione Transferases and Its Role in Cellular Resistance in Rat Brain Tumor Cells. Cancer Res. 1989; 49: 2621–2625
  • Glatt H., Friedberg T., Grover P.T., Sims P., Oesch F. Inactivation of a Diol-Epoxide and a K-Region Epoxide with High Efficiency by Glutathione Transferase X1. Cancer Res. 1983; 43: 5713–5717
  • Hernandez O., Bend J.R. Metabolism of Epoxides. Metabolic Basis of Detoxication, W.B. Jakoby, J.R. Bend, J. Caldwell. Academic Press, New York 1982; 207–225
  • Ketterer B. Protective Role of Glutathione and Glutathione Transferases in Mutagenesis and Carcinogenesis. Mutation Res. 1988; 202: 343–361
  • Jhee E.C., Ho L.L., Tsuji K., Gopalan P., Lotlikar P.D. Effect of Butylated Hydroxyanisole Pretreatment on Aflatoxin B1-DNA Binding and Aflatoxin-Glutathione Conjugation in Isolated Hepatocytes from Rats. Cancer Res. 1989; 49: 1357–1360

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