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ORIGINAL INVESTIGATIONS

Visual cortex abnormalities in adults with ADHD: A structural MRI study

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Pages 260-270 | Received 14 Feb 2010, Accepted 23 Aug 2010, Published online: 29 Sep 2010

References

  • Alexander GE, DeLong MR, Strick PL. 1986. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357–381.
  • American Psychiatric Association. 1994. Diagnostic and Statistical Manual of Mental Disorders. Washington, DC: American Psychiatric Press.
  • Ashburner J, Friston KJ. 2000. Voxel-based morphometry – the methods. Neuroimage 11:805–821.
  • Barkley RA. 1997. Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull 121:65–94.
  • Beck AT, Steer RA. 1987. Manual for the Revised Beck Depression Inventory. San Antonio, TX: Psychological Corporation.
  • Beck DM, Kastner S. 2005. Stimulus context modulates competition in human extrastriate cortex. Nat Neurosci 8:1110–1116.
  • Biederman J, Mick E, Faraone SV. 2000. Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type. Am J Psychiatry 157:816–818.
  • Biederman J, Makris N, Valera EM, Monuteaux MC, Goldstein JM, Buka S, . 2008. Towards further understanding of the co-morbidity between attention deficit hyperactivity disorder and bipolar disorder: a MRI study of brain volumes. Psychol Med 38:1045–1056.
  • Bookstein FL. 2001. “Voxel-based morphometry” should not be used with imperfectly registered images. Neuroimage 14: 1454–1462.
  • Booth JR, Burman DD, Meyer JR, Lei Z, Trommer BL, Davenport ND, . 2005. Larger deficits in brain networks for response inhibition than for visual selective attention in attention deficit hyperactivity disorder (ADHD). J Child Psychol Psychiatry 46:94–111.
  • Brieber S, Neufang S, Bruning N, Kamp-Becker I, Remschmidt H, Herpertz-Dahlmann B, . 2007. Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder. J Child Psychol Psychiatry 48:1251–1258.
  • Bullier J, Hupe JM, James AC, Girard P. 2001. The role of feedback connections in shaping the responses of visual cortical neurons. Prog Brain Res 134:193–204.
  • Carmona S, Vilarroya O, Bielsa A, Tremols V, Soliva JC, Rovira M, . 2005. Global and regional gray matter reductions in ADHD: a voxel-based morphometric study. Neurosci Lett 389:88–93.
  • Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS, . 2002. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. J Am Med Assoc 288: 1740–1748.
  • Corbetta M, Shulman GL. 2002. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 3:201–215.
  • Desimone R, Duncan J. 1995. Neural mechanisms of selective visual attention. Annu Rev Neurosci 18:193–222.
  • Douaud G, Gaura V, Ribeiro MJ, Lethimonnier F, Maroy R, Verny C, . 2006. Distribution of grey matter atrophy in Huntington's disease patients: a combined ROI-based and voxel-based morphometric study. Neuroimage 32:1562–1575.
  • Durston S, Hulshoff Pol HE, Schnack HG, Buitelaar JK, Steenhuis MP, Minderaa RB, . 2004. Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings. J Am Acad Child Adolesc Psychiatry 43:332–340.
  • Ebert D, Krause J, Roth-Sackenheim C. 2003. ADHD in adulthood – guidelines based on expert consensus with DGPPN support. Nervenarzt 74:939–946.
  • Eickhoff SB, Stephan KE, Mohlberg H, Grefkes C, Fink GR, Amunts K, . 2005. A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data. Neuroimage 25:1325–1335.
  • Ellison-Wright I, Ellison-Wright Z, Bullmore E. 2008. Structural brain change in Attention deficit hyperactivity disorder identified by meta-analysis. BMC Psychiatry 8:51.
  • Epstein JN, Conners CK, Erhardt D, March JS, Swanson JM. 1997. Asymmetrical hemispheric control of visual-spatial attention in adults with attention deficit hyperactivity disorder. Neuropsychology 11:467–473.
  • Fayyad J, De Graaf R, Kessler R, Alonso J, Angermeyer M, Demyttenaere K, . 2007. Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. Br J Psychiatry 190:402–409.
  • Filipek PA, Semrud-Clikeman M, Steingard RJ, Renshaw PF, Kennedy DN, Biederman J. 1997. Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls. Neurology 48:589–601.
  • First MB, Gibbon M, Spitzer RL, Williams JB, Smith BL. 1997. Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II). Washington, DC: American Psychiatric Press.
  • Frodl T, Stauber J, Schaaff N, Koutsouleris N, Scheuerecker J, Ewers M, . 2010. Amygdala reduction in patients with ADHD compared with major depression and healthy volunteers. Acta Psychiatr Scand 121:111–118.
  • Genovese CR, Lazar NA, Nichols T. 2002. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 15:870–878.
  • Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. 2001. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 14: 21–36.
  • Good CD, Scahill RI, Fox NC, Ashburner J, Friston KJ, Chan D, . 2002. Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias. Neuroimage 17:29–46.
  • Hervey AS, Epstein JN, Curry JF. 2004. Neuropsychology of adults with attention-deficit/hyperactivity disorder: a meta-analytic review. Neuropsychology 18:485–503.
  • Hesslinger B, Tebartz van Elst L, Thiel T, Haegele K, Hennig J, Ebert D. 2002. Frontoorbital volume reductions in adult patients with attention deficit hyperactivity disorder. Neurosci Lett 328:319–321.
  • Hochstein S, Ahissar M. 2002. View from the top: hierarchies and reverse hierarchies in the visual system. Neuron 36:791–804.
  • Hopf JM, Noesselt T, Tempelmann C, Braun J, Schoenfeld MA, Heinze HJ. 2004. Popout modulates focal attention in the primary visual cortex. Neuroimage 22:574–582.
  • Kamitani Y, Tong F. 2005. Decoding the visual and subjective contents of the human brain. Nat Neurosci 8:679–685.
  • Kastner S, Ungerleider LG. 2000. Mechanisms of visual attention in the human cortex. Annu Rev Neurosci 23:315–341.
  • Keller SS, Wilke M, Wieshmann UC, Sluming VA, Roberts N. 2004. Comparison of standard and optimized voxel-based morphometry for analysis of brain changes associated with temporal lobe epilepsy. Neuroimage 23:860–868.
  • Konrad K, Neufang S, Hanisch C, Fink GR, Herpertz-Dahlmann B. 2006. Dysfunctional attentional networks in children with attention deficit/hyperactivity disorder: evidence from an event-related functional magnetic resonance imaging study. Biol Psychiatry 59:643–651.
  • Krause KH, Krause J, Trott GE. 1998. Hyperkinetic syndrome (attention deficit hyperactivity disorder) in adulthood. Nervenarzt 69:543–556.
  • Makris N, Biederman J, Valera EM, Bush G, Kaiser J, Kennedy DN, . 2007. Cortical thinning of the attention and executive function networks in adults with attention-deficit/hyperactivity disorder. Cereb Cortex 17:1364–1375.
  • Makris N, Seidman LJ, Valera EM, Biederman J, Monuteaux MC, Kennedy DN, . 2010. Anterior cingulate volumetric alterations in treatment-naive adults with ADHD: a pilot study. J Atten Disord 13:407–413.
  • Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. 2003. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19: 1233–1239.
  • Martinez A, Anllo-Vento L, Sereno MI, Frank LR, Buxton RB, Dubowitz DJ, . 1999. Involvement of striate and extrastriatevisual cortical areas in spatial attention. Nat Neurosci 2:364–369.
  • McAlonan GM, Cheung V, Cheung C, Chua SE, Murphy DG, Suckling J, . 2007. Mapping brain structure in attention deficit-hyperactivity disorder: a voxel-based MRI study of regional grey and white matter volume. Psychiatry Res 154: 171–180.
  • Mega MS, Cummings JL. 1994. Frontal-subcortical circuits and neuropsychiatric disorders. J Neuropsychiatry Clin Neurosci 6:358–370.
  • Mostofsky SH, Cooper KL, Kates WR, Denckla MB, Kaufmann WE. 2002. Smaller prefrontal and premotor volumes in boys with attention-deficit/hyperactivity disorder. Biol Psychiatry 52:785–794.
  • Overmeyer S, Bullmore ET, Suckling J, Simmons A, Williams SC, Santosh PJ, . 2001. Distributed grey and white matter deficits in hyperkinetic disorder: MRI evidence for anatomical abnormality in an attentional network. Psychol Med 31:1425–1435.
  • Paradiso MA. 2002. Perceptual and neuronal correspondence in primary visual cortex. Curr Opin Neurobiol 12:155–161.
  • Pascual-Leone A, Walsh V. 2001. Fast backprojections from the motion to the primary visual area necessary for visual awareness. Science 292:510–512.
  • Perchet C, Revol O, Fourneret P, Mauguiere F, Garcia-Larrea L. 2001. Attention shifts and anticipatory mechanisms in hyperactive children: an ERP study using the Posner paradigm. Biol Psychiatry 50:44–57.
  • Perlov E, Philipsen A, Tebartz van Elst L, Ebert D, Henning J, Maier S, . 2008. Hippocampus and amygdala morphology in adults with attention-deficit hyperactivity disorder. J Psychiatry Neurosci 33:509–515.
  • Pessoa L, Kastner S, Ungerleider LG. 2003. Neuroimaging studies of attention: from modulation of sensory processing to top-down control. J Neurosci 23:3990–3998.
  • Posner MI, Gilbert CD. 1999. Attention and primary visual cortex. Proc Natl Acad Sci USA 96:2585–2587.
  • Posner MI, Petersen SE. 1990. The attention system of the human brain. Annu Rev Neurosci 13:25–42.
  • Reetz K, Lencer R, Steinlechner S, Gaser C, Hagenah J, Buchel C, . 2008. Limbic and frontal cortical degeneration is associated with psychiatric symptoms in PINK1 mutation carriers. Biol Psychiatry 64:241–247.
  • Ress D, Backus BT, Heeger DJ. 2000. Activity in primary visual cortex predicts performance in a visual detection task. Nat Neurosci 3:940–945.
  • Rösler M, Retz W, Retz-Junginger P, Thome J, Supprian T, Nissen T, . 2004. Tools for the diagnosis of attention-deficit/hyperactivity disorder in adults. Self-rating behaviour questionnaire and diagnostic checklist. Nervenarzt 75:888–895.
  • Rubia K, Smith AB, Brammer MJ, Taylor E. 2007. Temporal lobe dysfunction in medication-naive boys with attention-deficit/hyperactivity disorder during attention allocation and its relation to response variability. Biol Psychiatry 62:999–1006.
  • Rüsch N, Tebartz van Elst L, Ludaescher P, Wilke M, Huppertz HJ, Thiel T, . 2003. A voxel-based morphometric MRI study in female patients with borderline personality disorder. Neuroimage 20:385–392.
  • Salmond CH, Ashburner J, Vargha-Khadem F, Connelly A, Gadian DG, Friston KJ. 2002. The precision of anatomical normalization in the medial temporal lobe using spatial basis functions. Neuroimage 17:507–512.
  • Schöchlin C, Engel RR. 2005. Neuropsychological performance in adult attention-deficit hyperactivity disorder: Meta-analysis of empirical data. Arch Clin Neuropsychol 20:727–744.
  • Seidman LJ. 2006. Neuropsychological functioning in people with ADHD across the lifespan. Clin Psychol Rev 26:466–485.
  • Seidman LJ, Valera EM, Makris N. 2005. Structural brain imaging of attention-deficit/hyperactivity disorder. Biol Psychiatry 57:1263–1272.
  • Seidman LJ, Valera EM, Makris N, Monuteaux MC, Boriel DL, Kelkar K, . 2006. Dorsolateral prefrontal and anterior cingulate cortex volumetric abnormalities in adults with attention-deficit/hyperactivity disorder identified by magnetic resonance imaging. Biol Psychiatry 60:1071–1080.
  • Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A, . 2006. Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 63:540–549.
  • Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Greenstein D, . 2007. Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci USA 104:19649–19654.
  • Shaw P, Lalonde F, Lepage C, Rabin C, Eckstrand K, Sharp W, . 2009a. Development of cortical asymmetry in typically developing children and its disruption in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 66:888–896.
  • Shaw P, Sharp WS, Morrison M, Eckstrand K, Greenstein DK, Clasen LS, . 2009b. Psychostimulant treatment and the developing cortex in attention deficit hyperactivity disorder. Am J Psychiatry 166:58–63.
  • Shen S, Szameitat AJ, Sterr A. 2007. VBM lesion detection depends on the normalization template: a study using simulated atrophy. Magn Reson Imaging 25:1385–1396.
  • Shuter B, Yeh IB, Graham S, Au C, Wang SC. 2008. Reproducibility of brain tissue volumes in longitudinal studies: effects of changes in signal-to-noise ratio and scanner software. Neuroimage 41:371–379.
  • Silver MA, Ress D, Heeger DJ. 2007. Neural correlates of sustained spatial attention in human early visual cortex. J Neurophysiol 97:229–237.
  • Smith AB, Taylor E, Brammer M, Toone B, Rubia K. 2006. Task-specific hypoactivation in prefrontal and temporoparietal brain regions during motor inhibition and task switching in medication-naive children and adolescents with attention deficit hyperactivity disorder. Am J Psychiatry 163:1044–1051.
  • Somers DC, Dale AM, Seiffert AE, Tootell RB. 1999. Functional MRI reveals spatially specific attentional modulation in human primary visual cortex. Proc Natl Acad Sci USA 96: 1663–1668.
  • Sowell ER, Thompson PM, Welcome SE, Henkenius AL, Toga AW, Peterson BS. 2003. Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet 362:1699–1707.
  • Stein MA, Sandoval R, Szumowski E, Roizen N, Reinecke MA, Blondis TA, . 1995. Psychometric characteristics of the Wender Utah Rating Scale (WURS): reliability and factor structure for men and women. Psychopharmacol Bull 31:425–433.
  • Tamm L, Menon V, Reiss AL. 2006. Parietal attentional system aberrations during target detection in adolescents with attention deficit hyperactivity disorder: event-related fMRI evidence. Am J Psychiatry 163:1033–1043.
  • Treue S. 2001. Neural correlates of attention in primate visual cortex. Trends Neurosci 24:295–300.
  • Tucha O, Walitza S, Mecklinger L, Sontag TA, Kubber S, Linder M, . 2006. Attentional functioning in children with ADHD–predominantly hyperactive-impulsive type and children with ADHD–combined type. J Neural Transm 113:1943–1953.
  • Valera EM, Faraone SV, Murray KE, Seidman LJ. 2007. Meta-analysis of structural imaging findings in attention-deficit/hyperactivity disorder. Biol Psychiatry 61:1361–1369.
  • van der Stelt O, van der Molen M, Boudewijn Gunning W, Kok A. 2001. Neuroelectrical signs of selective attention to color in boys with attention-deficit hyperactivity disorder. Brain Res Cogn Brain Res 12:245–264.
  • Vance A, Silk TJ, Casey M, Rinehart NJ, Bradshaw JL, Bellgrove MA, . 2007. Right parietal dysfunction in children with attention deficit hyperactivity disorder, combined type: a functional MRI study. Mol Psychiatry 12:826–832, 793.
  • Ward MF, Wender PH, Reimherr FW. 1993. The Wender Utah Rating Scale: an aid in the retrospective diagnosis of childhood attention deficit hyperactivity disorder. Am J Psychiatry 150: 885–890.
  • Wilke M, Schmithorst VJ, Holland SK. 2002. Assessment of spatial normalization of whole-brain magnetic resonance images in children. Hum Brain Mapp 17:48–60.
  • Wilke M, Holland SK, Altaye M, Gaser C. 2008. Template-O-Matic: a toolbox for creating customized pediatric templates. Neuroimage 41:903–913.
  • Willcutt EG, Doyle AE, Nigg JT, Faraone SV, Pennington BF. 2005. Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biol Psychiatry 57:1336–1346.
  • Wolosin SM, Richardson ME, Hennessey JG, Denckla MB, Mostofsky SH. 2009. Abnormal cerebral cortex structure in children with ADHD. Hum Brain Mapp 30:175–184.
  • Wood C, Maruff P, Levy F, Farrow M, Hay D. 1999. Covert orienting of visual spatial attention in attention deficit hyperactivity disorder: does comorbidity make a difference? Arch Clin Neuropsychol 14:179–189.
  • Yang P, Wang PN, Chuang KH, Jong YJ, Chao TC, Wu MT. 2008. Absence of gender effect on children with attention-deficit/hyperactivity disorder as assessed by optimized voxel-based morphometry. Psychiatry Res Neuroimaging 164:245–253.

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