Candidate pathway association study in cocaine dependence: The control of neurotransmitter release

References

• Ahmed SH, Lutjens R, van der Stap LD, Lekic D, Romano-Spica V, Morales M, . 2005. Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction. Proc Natl Acad Sci USA 102(32):11533–11538.
   PubMed Web of Science ®Google Scholar
• Ballon N, Leroy S, Roy C, Bourdel MC, Charles-Nicolas A, Krebs MO, . 2006. (AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population. Pharmacogenomics J 6(2):126–130.
   PubMed Web of Science ®Google Scholar
• Ballon N, Leroy S, Roy C, Bourdel MC, Olie JP, Charles-Nicolas A, . 2007. Polymorphisms TaqI A of the DRD2, BalI of the DRD3, exon III repeat of the DRD4, and 3′ UTR VNTR of the DAT: association with childhood ADHD in male African-Caribbean cocaine dependents? Am J Med Genet B Neuropsychiatr Genet 144B(8):1034–1041.
   PubMed Web of Science ®Google Scholar
• Barszczewski M, Chua JJ, Stein A, Winter U, Heintzmann R, Zilly FE, . 2008. A novel site of action for alpha-SNAP in the SNARE conformational cycle controlling membrane fusion. Mol Biol Cell 19(3):776–784.
   PubMed Web of Science ®Google Scholar
• Bomberger JM, Parameswaran N, Hall CS, Aiyar N, Spielman WS. 2005. Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. J Biol Chem 280(10):9297–9307.
   PubMed Web of Science ®Google Scholar
• Brookes KJ, Knight J, Xu X, Asherson P. 2005. DNA pooling analysis of ADHD and genes regulating vesicle release of neurotransmitters. Am J Med Genet B Neuropsychiatr Genet 139B(1):33–37.
   PubMed Web of Science ®Google Scholar
• Comings DE, Blum K. 2000. Reward deficiency syndrome: genetic aspects of behavioral disorders. Prog Brain Res 126: 325–341.
   PubMed Web of Science ®Google Scholar
• Comings DE, Gonzalez N, Wu S, Saucier G, Johnson P, Verde R, . 1999. Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence. Mol Psychiatry 4(5):484–487.
   PubMed Web of Science ®Google Scholar
• Cong M, Perry SJ, Hu LA, Hanson PI, Claing A, Lefkowitz RJ. 2001. Binding of the beta2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recycling. J Biol Chem 276(48):45145–45152.
   PubMed Web of Science ®Google Scholar
• Cornish JL, Kalivas PW. 2000. Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. J Neurosci 20(15):RC89.
   PubMed Web of Science ®Google Scholar
• Cubells JF, Kranzler HR, McCance-Katz E, Anderson GM, Malison RT, Price LH, . 2000. A haplotype at the DBH locus, associated with low plasma dopamine beta–hydroxylase activity, also associates with cocaine-induced paranoia. Mol Psychiatry 5(1):56–63.
   PubMed Web of Science ®Google Scholar
• Dackis C, O'Brien C. 2003. Glutamatergic agents for cocaine dependence. Ann NY Acad Sci 1003:328–345.
   PubMed Web of Science ®Google Scholar
• Dackis CA, Lynch KG, Yu E, Samaha FF, Kampman KM, Cornish JW, . 2003. Modafinil and cocaine: a double-blind, placebo-controlled drug interaction study. Drug Alcohol Depend 70(1):29–37.
   PubMed Web of Science ®Google Scholar
• De Vries TJ, Schoffelmeer AN. 2005. Cannabinoid CB1 receptors control conditioned drug seeking. Trends Pharmacol Sci 26(8):420–426.
   PubMed Web of Science ®Google Scholar
• De Vries TJ, Shaham Y, Homberg JR, Crombag H, Schuurman K, Dieben J, . 2001. A cannabinoid mechanism in relapse to cocaine seeking. Nat Med 7(10):1151–1154.
   PubMed Web of Science ®Google Scholar
• Dewey SL, Chaurasia CS, Chen CE, Volkow ND, Clarkson FA, Porter SP, . 1997. GABAergic attenuation of cocaine-induced dopamine release and locomotor activity. Synapse 25(4):393–398.
   PubMed Web of Science ®Google Scholar
• Di Ciano P, Underwood RJ, Hagan JJ, Everitt BJ. 2003. Attenuation of cue-controlled cocaine-seeking by a selective D3 dopamine receptor antagonist SB-277011-A. Neuropsychopharmacology 28(2):329–338.
   PubMed Web of Science ®Google Scholar
• Dudbridge F. 2003. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 25(2):115–121.
   PubMed Web of Science ®Google Scholar
• Fernàndez-Castillo N, Ribasés M, Roncero C, Casas M, Gonzalvo B, Cormand B. 2010. Association study between the DAT1, DBH and DRD2 genes and cocaine dependence in a Spanish sample. Psychiatr Genet 20(6):317–320.
   PubMed Web of Science ®Google Scholar
• Filip M. 2005. Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats. Pharmacol Rep 57(1):35–46.
   PubMed Web of Science ®Google Scholar
• Filip M, Nowak E, Papla I. 2001. On the role of serotonin2A/2C receptors in the sensitization to cocaine. J Physiol Pharmacol 52(3):471–481.
   PubMed Web of Science ®Google Scholar
• Filip M, Bubar MJ, Cunningham KA. 2004. Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses. J Pharmacol Exp Ther 310(3):1246–1254.
   PubMed Web of Science ®Google Scholar
• First MB, Spitzer RL, Gibbon M, Williams JBW (1997). Structured Clinical Interview for DSM-IV disorders (SCID-IV). Washington, DC: American Psychiatric Press.
   Google Scholar
• Freeman WM, Brebner K, Patel KM, Lynch WJ, Roberts DC, Vrana KE. 2002. Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression. Neurochem Res 27(10):1181–1192.
   PubMed Web of Science ®Google Scholar
• Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, . 2002. The structure of haplotype blocks in the human genome. Science 296(5576):2225–2229.
   PubMed Web of Science ®Google Scholar
• Gass JT, Olive MF. 2008. Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol 75(1):218–265.
   PubMed Web of Science ®Google Scholar
• Gonzalez G, Sevarino K, Sofuoglu M, Poling J, Oliveto A, Gonsai K, . 2003. Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study. Addiction 98(11):1625–1632.
   PubMed Web of Science ®Google Scholar
• Gonzalez JR, Armengol L, Sole X, Guino E, Mercader JM, Estivill X, . 2007. SNPassoc: an R package to perform whole genome association studies. Bioinformatics 23(5):644–645.
   PubMed Web of Science ®Google Scholar
• Grucza RA, Wang JC, Stitzel JA, Hinrichs AL, Saccone SF, Saccone NL, . 2008. A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biol Psychiatry 64(11):922–929.
   PubMed Web of Science ®Google Scholar
• Guindalini C, Howard M, Haddley K, Laranjeira R, Collier D, Ammar N, . 2006. A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample. Proc Natl Acad Sci USA 103(12):4552–4557.
   PubMed Web of Science ®Google Scholar
• Guindalini C, Laranjeira R, Collier D, Messas G, Vallada H, Breen G. 2008. Dopamine-beta hydroxylase polymorphism and cocaine addiction. Behav Brain Funct 4:1.
   PubMed Web of Science ®Google Scholar
• Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, . 2002. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience 115(1):153–161.
   PubMed Web of Science ®Google Scholar
• Hall FS, Sora I, Drgonova J, Li XF, Goeb M, Uhl GR. 2004. Molecular mechanisms underlying the rewarding effects of cocaine. Ann NY Acad Sci 1025:47–56.
   PubMed Web of Science ®Google Scholar
• Hart CL, Haney M, Vosburg SK, Rubin E, Foltin RW. 2008. Smoked cocaine self-administration is decreased by modafinil. Neuropsychopharmacology 33(4):761–768.
   PubMed Web of Science ®Google Scholar
• Heydorn A, Sondergaard BP, Hadrup N, Holst B, Haft CR, Schwartz TW. 2004. Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting. FEBS Lett 556(1–3):276–280.
   PubMed Web of Science ®Google Scholar
• Kalivas PW. 2007. Neurobiology of cocaine addiction: implications for new pharmacotherapy. Am J Addict 16(2):71–78.
   PubMed Web of Science ®Google Scholar
• Kalivas PW, O'Brien C. 2008. Drug addiction as a pathology of staged neuroplasticity. Neuropsychopharmacology 33(1): 166–180.
   PubMed Web of Science ®Google Scholar
• Kendler KS, Prescott CA. 1998. Cocaine use, abuse and dependence in a population-based sample of female twins. Br J Psychiatry 173:345–350.
   PubMed Web of Science ®Google Scholar
• Kendler KS, Karkowski LM, Neale MC, Prescott CA. 2000. Illicit psychoactive substance use, heavy use, abuse, and dependence in a US population-based sample of male twins. Arch Gen Psychiatry 57(3):261–269.
   PubMed Web of Science ®Google Scholar
• Kuhar MJ, Ritz MC, Boja JW. 1991. The dopamine hypothesis of the reinforcing properties of cocaine. Trends Neurosci 14(7): 299–302.
   PubMed Web of Science ®Google Scholar
• Littleton JT, Barnard RJ, Titus SA, Slind J, Chapman ER, Ganetzky B. 2001. SNARE-complex disassembly by NSF follows synaptic-vesicle fusion. Proc Natl Acad Sci USA 98(21):12233–12238.
   PubMed Web of Science ®Google Scholar
• Malcolm R, Swayngim K, Donovan JL, DeVane CL, Elkashef A, Chiang N, . 2006. Modafinil and cocaine interactions. Am J Drug Alcohol Abuse 32(4):577–587.
   PubMed Web of Science ®Google Scholar
• Malsam J, Kreye S, Sollner TH. 2008. Membrane fusion: SNAREs and regulation. Cell Mol Life Sci 65(18):2814–2832.
   PubMed Web of Science ®Google Scholar
• Mannelli P, Patkar AA, Murray HW, Certa K, Peindl K, Mattila-Evenden M, . 2005. Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals. Addict Biol 10(3): 261–268.
   PubMed Web of Science ®Google Scholar
• Miller SA, Dykes DD, Polesky HF. 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16(3):1215.
   PubMed Web of Science ®Google Scholar
• Morgan AE, Dewey SL. 1998. Effects of pharmacologic increases in brain GABA levels on cocaine-induced changes in extracellular dopamine. Synapse 28(1):60–65.
   PubMed Web of Science ®Google Scholar
• Nishimune A, Isaac JT, Molnar E, Noel J, Nash SR, Tagaya M, . 1998. NSF binding to GluR2 regulates synaptic transmission. Neuron 21(1):87–97.
   PubMed Web of Science ®Google Scholar
• Noble EP, Blum K, Khalsa ME, Ritchie T, Montgomery A, Wood RC, . 1993. Allelic association of the D2 dopamine receptor gene with cocaine dependence. Drug Alcohol Depend 33(3):271–285.
   PubMed Web of Science ®Google Scholar
• O'Brien MS, Anthony JC. 2005. Risk of becoming cocaine dependent: epidemiological estimates for the United States, 2000–2001. Neuropsychopharmacology 30(5):1006–1018.
   PubMed Web of Science ®Google Scholar
• Osten P, Srivastava S, Inman GJ, Vilim FS, Khatri L, Lee LM, . 1998. The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs. Neuron 21(1):99–110.
   PubMed Web of Science ®Google Scholar
• Patkar AA, Berrettini WH, Hoehe M, Hill KP, Sterling RC, Gottheil E, . 2001. Serotonin transporter (5-HTT) gene polymorphisms and susceptibility to cocaine dependence among African-American individuals. Addict Biol 6(4):337–345.
   PubMed Web of Science ®Google Scholar
• Pontier SM, Lahaie N, Ginham R, St-Gelais F, Bonin H, Bell DJ, . 2006. Coordinated action of NSF and PKC regulates GABAB receptor signaling efficacy. Embo J 25(12):2698–2709.
   PubMed Web of Science ®Google Scholar
• Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira M, Bender D, . 2007. PLINK: a toolset for whole-genome association and population-based linkage analysis. Am J Hum Genet 81(3): 559–575.
   PubMed Web of Science ®Google Scholar
• Rizo J, Rosenmund C. 2008. Synaptic vesicle fusion. Nat Struct Mol Biol 15(7):665–674.
   PubMed Web of Science ®Google Scholar
• Schweizer FE, Dresbach T, DeBello WM, O'Connor V, Augustine GJ, Betz H. 1998. Regulation of neurotransmitter release kinetics by NSF. Science 279(5354):1203–1206.
   PubMed Web of Science ®Google Scholar
• Song I, Kamboj S, Xia J, Dong H, Liao D, Huganir RL. 1998. Interaction of the N-ethylmaleimide-sensitive factor with AMPA receptors. Neuron 21(2):393–400.
   PubMed Web of Science ®Google Scholar
• Sora I, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, . 1998. Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc Natl Acad Sci USA 95(13):7699–7704.
   PubMed Web of Science ®Google Scholar
• Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, . 2001. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Natl Acad Sci USA 98(9):5300–5305.
   PubMed Web of Science ®Google Scholar
• Soria G, Mendizabal V, Tourino C, Robledo P, Ledent C, Parmentier M, . 2005. Lack of CB1 cannabinoid receptor impairs cocaine self-administration. Neuropsychopharmacology 30(9):1670–1680.
   PubMed Web of Science ®Google Scholar
• Spealman RD. 1993. Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology (Berlin) 112(1):93–99.
   PubMed Web of Science ®Google Scholar
• Stephens M, Smith NJ, Donnelly P. 2001. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68(4):978–989.
   PubMed Web of Science ®Google Scholar
• Storey J. 2002. A direct approach to false discovery Rates. J R Stat Soc Ser B 64:479–498.
   Google Scholar
• Thomas MJ, Kalivas PW, Shaham Y. 2008. Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br J Pharmacol 154(2):327–342.
   PubMed Web of Science ®Google Scholar
• Thorisson GA, Smith AV, Krishnan L, Stein LD. 2005. The International HapMap Project Web site. Genome Res 15(11): 1592–1593.
   PubMed Web of Science ®Google Scholar
• Tsuang MT, Lyons MJ, Meyer JM, Doyle T, Eisen SA, Goldberg J, . 1998. Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. Arch Gen Psychiatry 55(11):967–972.
   PubMed Web of Science ®Google Scholar
• Uhl GR, Hall FS, Sora I. 2002. Cocaine, reward, movement and monoamine transporters. Mol Psychiatry 7(1):21–26.
   PubMed Web of Science ®Google Scholar
• Uys JD, LaLumiere RT. 2008. Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS Neurol Disord Drug Targets 7(5):482–491.
   PubMed Web of Science ®Google Scholar
• Volkow ND, Wang GJ, Fowler JS, Gatley SJ, Ding YS, Logan J, . 1996. Relationship between psychostimulant-induced “high” and dopamine transporter occupancy. Proc Natl Acad Sci USA 93(19):10388–10392.
   PubMed Web of Science ®Google Scholar
• Volkow ND, Fowler JS, Wang GJ. 1999. Imaging studies on the role of dopamine in cocaine reinforcement and addiction in humans. J Psychopharmacol 13(4):337–345.
   PubMed Web of Science ®Google Scholar
• Volkow ND, Fowler JS, Wang GJ, Goldstein RZ. 2002. Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. Neurobiol Learn Mem 78(3):610–624.
   PubMed Web of Science ®Google Scholar
• Vorel SR, Ashby CR Jr, Paul M, Liu X, Hayes R, Hagan JJ, . 2002. Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats. J Neurosci 22(21):9595–9603.
   PubMed Web of Science ®Google Scholar
• Wagner FA, Anthony JC. 2002. From first drug use to drug dependence; developmental periods of risk for dependence upon marijuana, cocaine, and alcohol. Neuropsychopharmacology 26(4):479–488.
   PubMed Web of Science ®Google Scholar
• Walsh SL, Cunningham KA. 1997. Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine. Psychopharmacology (Berlin) 130(1): 41–58.
   PubMed Web of Science ®Google Scholar
• Woolverton WL, Johnson KM. 1992. Neurobiology of cocaine abuse. Trends Pharmacol Sci 13(5):193–200.
   PubMed Web of Science ®Google Scholar
• Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, . 2000. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nat Neurosci 3(5): 465–471.
   PubMed Web of Science ®Google Scholar
• Yuferov V, Kroslak T, Laforge KS, Zhou Y, Ho A, Kreek MJ. 2003. Differential gene expression in the rat caudate putamen after “binge” cocaine administration: advantage of triplicate microarray analysis. Synapse 48(4):157–169.
   PubMed Web of Science ®Google Scholar
• Zuo L, Kranzler HR, Luo X, Yang BZ, Weiss R, Brady K, . 2009. Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample. Neuropsychopharmacology 34(6):1504–1513.
   PubMed Web of Science ®Google Scholar